Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   HB752_RS02525 Genome accession   NZ_CP050271
Coordinates   485185..485892 (+) Length   235 a.a.
NCBI ID   WP_002262930.1    Uniprot ID   -
Organism   Streptococcus mutans strain S1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 480185..490892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB752_RS02495 (HB752_02495) - 480675..480863 (+) 189 WP_002264826.1 DNA-directed RNA polymerase subunit beta -
  HB752_RS02500 (HB752_02500) endA 480905..481786 (+) 882 WP_002264825.1 DNA/RNA non-specific endonuclease Machinery gene
  HB752_RS02505 (HB752_02505) - 481854..482504 (-) 651 WP_002262934.1 amino acid ABC transporter permease -
  HB752_RS02510 (HB752_02510) - 482519..483223 (-) 705 WP_002266143.1 amino acid ABC transporter permease -
  HB752_RS02515 (HB752_02515) - 483241..484053 (-) 813 WP_002262932.1 transporter substrate-binding domain-containing protein -
  HB752_RS02520 (HB752_02520) - 484050..484832 (-) 783 WP_002262931.1 amino acid ABC transporter ATP-binding protein -
  HB752_RS02525 (HB752_02525) vicR 485185..485892 (+) 708 WP_002262930.1 response regulator YycF Regulator
  HB752_RS02530 (HB752_02530) vicK 485885..487237 (+) 1353 WP_002264821.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HB752_RS02535 (HB752_02535) vicX 487234..488037 (+) 804 WP_019804853.1 MBL fold metallo-hydrolase Regulator
  HB752_RS02540 (HB752_02540) rnc 488144..488839 (+) 696 WP_002266141.1 ribonuclease III -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26914.70 Da        Isoelectric Point: 4.8288

>NTDB_id=431112 HB752_RS02525 WP_002262930.1 485185..485892(+) (vicR) [Streptococcus mutans strain S1]
MKKILIVDDEKPISDIIKFNLAKEGYDTITAFDGREALSKYEEENPDLIILDLMLPELDGLEVAKEVRKNSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASGIPEIIIGDLQILPDAFVAKKRGTEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=431112 HB752_RS02525 WP_002262930.1 485185..485892(+) (vicR) [Streptococcus mutans strain S1]
ATGAAGAAAATTCTAATCGTTGACGATGAAAAACCAATTTCTGATATCATCAAGTTTAACTTGGCTAAGGAAGGTTATGA
CACGATTACAGCCTTTGATGGGCGTGAAGCATTAAGTAAATATGAAGAAGAAAATCCTGACTTGATTATATTGGACTTAA
TGTTACCAGAACTAGACGGTCTTGAAGTGGCTAAGGAAGTTAGAAAAAACAGCCATGTTCCAATTATTATGTTATCAGCT
AAAGACAGTGAGTTTGATAAGGTTATTGGTCTTGAAATTGGTGCTGATGATTATGTGACTAAACCTTTTTCTAATCGTGA
ATTACTGGCGCGTGTAAAAGCGCATCTTCGCCGTACTGAAAATATTGAATCCGCAGTGGCTGAGGAAAATGCTTCAGGTA
TACCTGAAATTATTATTGGGGACTTGCAAATCTTACCAGATGCTTTTGTTGCTAAAAAACGTGGAACAGAGGTAGAGTTA
ACTCACCGTGAGTTTGAGCTGTTGCATCACTTAGCGACACACACAGGTCAGGTGATGACGCGTGAACATTTACTTGAAAC
GGTTTGGGGCTATGATTATTTTGGAGATGTCCGTACTGTTGATGTCACTGTTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCAGAGTACATTTTGACGCGACGCGGTGTTGGTTATTACATGAAATCATATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

100

100

1
  micA Streptococcus pneumoniae Cp1015

78.541

99.149

0.779
  covR Streptococcus salivarius strain HSISS4

45.923

99.149

0.455
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.887

98.298

0.451