Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   HB752_RS00550 Genome accession   NZ_CP050271
Coordinates   110635..112926 (+) Length   763 a.a.
NCBI ID   WP_019804902.1    Uniprot ID   -
Organism   Streptococcus mutans strain S1     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 105635..117926
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB752_RS00530 (HB752_00530) serS 105936..107210 (-) 1275 WP_002271339.1 serine--tRNA ligase -
  HB752_RS00535 (HB752_00535) - 107734..108807 (+) 1074 WP_002271340.1 acyltransferase -
  HB752_RS00540 (HB752_00540) - 109045..109413 (-) 369 WP_002263350.1 DUF956 family protein -
  HB752_RS00545 (HB752_00545) - 109732..110085 (+) 354 WP_002263351.1 hypothetical protein -
  HB752_RS00550 (HB752_00550) comA/nlmT 110635..112926 (+) 2292 WP_019804902.1 peptide cleavage/export ABC transporter Regulator
  HB752_RS00555 (HB752_00555) - 113258..114184 (-) 927 WP_002263353.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
  HB752_RS00560 (HB752_00560) - 114199..115017 (-) 819 WP_002263354.1 PTS mannose/fructose/sorbose transporter subunit IIC -
  HB752_RS00565 (HB752_00565) - 115052..116044 (-) 993 WP_002263355.1 PTS sugar transporter subunit IIB -
  HB752_RS00570 (HB752_00570) - 116921..117391 (-) 471 WP_002263356.1 hypothetical protein -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 86510.85 Da        Isoelectric Point: 7.1052

>NTDB_id=431101 HB752_RS00550 WP_019804902.1 110635..112926(+) (comA/nlmT) [Streptococcus mutans strain S1]
MNIFSYLLLTVVSVLLVNLFLEFIKYFFKTTPAMNKENSKKSSIFLWSRTRRFKFVPQVDNRDCGPAALASIAKHYGSYY
SLVHLRELTKTDRQGTTALGIIEAAKNIGFETYSLDADMSLFNYDDLIYPFIVHVVKNKRLQHYYVVYDDEGDSLIIGDP
DPSVKVIRMSKERFQHEWTGVAIFFSPKDDYQPQKDKRRGLTSFIPSFLKQKSLLFYIIMASLIITLIEIIGAFYLQVML
DEYIPSQKISTLGFITLGLIITYVAQQIIAFAKEYLLIILGQRLVIDVILTYIKHIFILPMSFFSTRRTGEITSRFTDAN
QIIDAVASTIFSIFLDISMVFIVGGVLLIQNVVLFFLALLCVPIYIIIVFAFMKMFGYLNYEVMESNAIMSSSVIEDING
IETIKSLTSEEVSYQRIDKEFVDFLEKSFRLHKYGAIQVSIKTAAKLILNIVILWYGARLVMTGKISVGQMIAFNVLLGY
FSSPIENMINLQIKLQSARIANTRLNEVYLVDSEFENNGELSEGSFLDGDISFEKLSYKYGYGRDTLSDINLTIKKGSKV
SLVGASGSGKTTLAKMIVNFYEPIQGLIRLNGYDLKDIDKTVLRQHINYLPQQAYVFSGTIMDNLTLGAKEDTIQEDIIR
ACEIAEIHSDIEQMPLGYQTELFDSTGVSGGQKQRIALARALLTQAPVLILDEATSSLDVLTEKKIVNNLMAMTNKTIVF
VAHRLSIAQRTDRIIVMDQGKIVEEGSHKELLAHKGFYYKLFN

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=431101 HB752_RS00550 WP_019804902.1 110635..112926(+) (comA/nlmT) [Streptococcus mutans strain S1]
ATGAACATATTTTCTTATCTTCTTTTGACTGTAGTTTCAGTATTATTAGTCAATTTATTCTTAGAATTTATAAAATACTT
TTTTAAAACAACTCCAGCAATGAATAAGGAAAATTCTAAGAAATCTTCAATTTTTTTGTGGAGTCGAACTAGACGTTTTA
AATTTGTACCACAAGTCGATAATAGAGACTGTGGCCCGGCTGCTCTAGCCTCTATTGCCAAACATTATGGTTCATATTAT
TCCTTGGTTCATCTGCGTGAACTTACAAAGACAGATCGACAAGGCACCACAGCATTAGGCATCATTGAAGCTGCCAAAAA
TATTGGATTTGAAACTTACTCGCTAGATGCTGATATGTCTTTATTTAATTATGATGACCTTATTTACCCTTTTATTGTTC
ACGTTGTTAAAAATAAACGTCTTCAACATTACTATGTTGTTTATGACGATGAAGGAGATAGTCTAATCATCGGAGATCCA
GATCCTTCTGTCAAAGTTATTCGCATGTCTAAGGAGAGATTTCAGCATGAATGGACAGGTGTAGCTATCTTCTTTTCCCC
AAAGGATGATTATCAGCCTCAAAAAGATAAAAGAAGAGGATTAACAAGTTTCATACCTTCTTTTTTAAAGCAAAAGAGTC
TCTTGTTCTATATTATAATGGCGAGTTTAATCATTACTTTAATAGAAATTATTGGAGCTTTTTATCTCCAAGTAATGCTG
GATGAGTATATTCCCAGTCAAAAAATTTCAACTTTAGGCTTTATCACTTTAGGATTAATAATAACTTATGTTGCCCAACA
AATAATAGCTTTTGCAAAAGAGTACTTATTAATTATATTAGGACAAAGGCTGGTAATTGATGTTATACTTACTTATATTA
AGCACATTTTTATTCTTCCGATGTCTTTTTTTTCGACAAGACGAACGGGAGAAATCACATCTCGCTTCACTGATGCCAAT
CAAATTATTGATGCTGTGGCGTCAACAATTTTTTCTATTTTCTTAGACATTTCGATGGTATTTATAGTTGGTGGAGTATT
ATTAATTCAAAATGTCGTTTTATTTTTCCTAGCCTTGCTCTGCGTTCCTATCTACATTATCATTGTTTTTGCATTTATGA
AAATGTTTGGTTACTTAAACTATGAGGTAATGGAAAGTAATGCGATAATGTCTTCATCTGTTATTGAGGATATTAATGGA
ATAGAAACTATCAAATCTTTGACGAGTGAAGAAGTTAGCTATCAGAGAATTGACAAGGAATTTGTTGATTTTTTAGAGAA
ATCTTTTAGGCTGCATAAGTATGGAGCTATTCAAGTCTCAATTAAAACTGCTGCAAAGCTAATTTTGAATATCGTTATTC
TATGGTATGGAGCACGATTGGTTATGACCGGGAAAATTTCAGTGGGTCAAATGATTGCTTTTAATGTGCTTTTAGGATAT
TTTTCAAGCCCAATTGAAAATATGATTAATTTACAAATTAAGCTCCAATCAGCCCGCATAGCTAATACGCGTCTCAATGA
AGTCTATCTGGTCGATTCTGAGTTTGAAAATAATGGGGAGCTTTCAGAAGGCAGCTTTTTGGATGGGGATATCTCTTTTG
AAAAGTTATCTTACAAGTATGGTTATGGTCGTGATACTCTGTCAGATATCAATCTAACTATTAAAAAAGGTTCAAAGGTC
AGTCTGGTCGGAGCCTCTGGTTCTGGTAAAACGACTCTTGCCAAGATGATTGTCAATTTTTATGAACCTATACAGGGTCT
TATCCGTCTTAATGGCTATGACCTAAAAGATATAGATAAGACTGTTTTACGCCAGCATATTAACTATCTCCCCCAACAAG
CTTATGTCTTTAGTGGTACCATTATGGATAATCTGACCTTGGGAGCCAAGGAAGACACTATTCAGGAAGATATTATTCGA
GCCTGTGAAATTGCTGAGATTCATTCAGACATTGAACAAATGCCGCTGGGGTACCAGACTGAGTTATTTGATAGTACTGG
AGTTTCCGGTGGCCAGAAGCAGCGGATTGCCTTGGCTCGCGCTCTCTTAACCCAAGCTCCAGTTTTGATTTTGGATGAAG
CCACCAGCAGTCTGGATGTCCTGACTGAAAAGAAAATCGTCAACAACCTCATGGCCATGACCAATAAGACTATTGTTTTT
GTGGCACACCGTTTGAGTATTGCTCAACGGACAGACCGAATTATTGTTATGGATCAAGGTAAGATTGTGGAAGAAGGTAG
CCATAAGGAACTTTTAGCTCATAAAGGCTTCTACTACAAGCTGTTTAACTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(215-484)

Peptidase C39 family (Peptidase_C39)

(53-189)

ABC transporter (ABC_tran)

(547-696)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.677

99.083

0.73
  comA Streptococcus mitis NCTC 12261

62.535

93.054

0.582
  comA Streptococcus pneumoniae Rx1

61.69

93.054

0.574
  comA Streptococcus pneumoniae D39

61.69

93.054

0.574
  comA Streptococcus pneumoniae R6

61.69

93.054

0.574
  comA Streptococcus mitis SK321

61.69

93.054

0.574
  comA Streptococcus pneumoniae TIGR4

61.408

93.054

0.571
  comA Streptococcus gordonii str. Challis substr. CH1

60.084

93.578

0.562