Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   HB753_RS00110 Genome accession   NZ_CP050270
Coordinates   25218..25652 (+) Length   144 a.a.
NCBI ID   WP_002274770.1    Uniprot ID   -
Organism   Streptococcus mutans strain S4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 20218..30652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB753_RS00080 (HB753_00080) - 21840..22223 (+) 384 WP_002263434.1 DUF1033 family protein -
  HB753_RS00085 (HB753_00085) comYA 22353..23294 (+) 942 WP_019804919.1 competence type IV pilus ATPase ComGA Machinery gene
  HB753_RS00090 (HB753_00090) comYB 23230..24261 (+) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  HB753_RS00095 (HB753_00095) comYC 24261..24575 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  HB753_RS00100 (HB753_00100) comYD 24562..24966 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  HB753_RS00105 (HB753_00105) comYE 24938..25231 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  HB753_RS00110 (HB753_00110) comYF 25218..25652 (+) 435 WP_002274770.1 competence type IV pilus minor pilin ComGF Machinery gene
  HB753_RS00115 (HB753_00115) comYG 25630..26019 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  HB753_RS00120 (HB753_00120) comYH 26074..27027 (+) 954 WP_019317550.1 class I SAM-dependent methyltransferase Machinery gene
  HB753_RS00125 (HB753_00125) - 27086..28285 (+) 1200 WP_002263443.1 acetate kinase -
  HB753_RS00130 (HB753_00130) tnpA 28498..28961 (+) 464 Protein_20 IS200/IS605 family transposase -
  HB753_RS00135 (HB753_00135) - 29589..29834 (+) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  HB753_RS00140 (HB753_00140) - 29803..30243 (+) 441 WP_002263445.1 hypothetical protein -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16251.78 Da        Isoelectric Point: 10.1806

>NTDB_id=431023 HB753_RS00110 WP_002274770.1 25218..25652(+) (comYF) [Streptococcus mutans strain S4]
MLKSKLKAFTLLECLLALLVIAGSVSVYNGLTKAISSNIHYLSKNQEDAWLLFCQQFRSELKGTTLQKLDSNKLYVQKNN
QSLAFGKSKASDFRKTNSDGRGYQPMLTEIKAANFSQSGKIIKLDLTFKDGLERTFVYAFHEKN

Nucleotide


Download         Length: 435 bp        

>NTDB_id=431023 HB753_RS00110 WP_002274770.1 25218..25652(+) (comYF) [Streptococcus mutans strain S4]
TTGTTAAAAAGTAAATTGAAAGCTTTCACACTTTTAGAGTGTCTCCTTGCTTTGCTTGTCATTGCTGGTAGTGTATCTGT
TTATAATGGTCTAACTAAAGCTATTAGTAGTAATATTCATTACTTATCAAAAAATCAAGAAGATGCTTGGTTACTTTTTT
GTCAGCAATTTCGGTCTGAACTTAAAGGAACGACTTTGCAAAAATTGGATAGCAATAAGCTTTATGTTCAAAAAAATAAT
CAAAGTTTAGCCTTTGGTAAATCAAAAGCAAGTGATTTTAGAAAGACTAACAGTGATGGACGTGGTTATCAGCCTATGTT
GACGGAGATCAAAGCTGCTAATTTTAGTCAATCAGGAAAAATTATTAAATTAGACCTTACTTTCAAAGATGGTTTAGAGA
GGACTTTTGTTTATGCTTTTCATGAAAAAAATTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(36-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

99.306

100

0.993
  comYF Streptococcus mutans UA159

98.611

100

0.986
  comGF Lactococcus lactis subsp. cremoris KW2

43.972

97.917

0.431
  comGF/cglF Streptococcus pneumoniae Rx1

40.299

93.056

0.375
  comGF/cglF Streptococcus pneumoniae D39

40.299

93.056

0.375
  comGF/cglF Streptococcus pneumoniae R6

40.299

93.056

0.375
  comGF/cglF Streptococcus pneumoniae TIGR4

40.299

93.056

0.375
  comGF/cglF Streptococcus mitis NCTC 12261

38.806

93.056

0.361