Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HBA50_RS02055 Genome accession   NZ_CP050133
Coordinates   395709..396452 (+) Length   247 a.a.
NCBI ID   WP_005591765.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 390709..401452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS02040 (HBA50_02040) - 391075..392640 (-) 1566 WP_045500704.1 ABC transporter substrate-binding protein/permease -
  HBA50_RS02045 (HBA50_02045) - 392831..394666 (+) 1836 WP_243746225.1 DUF2207 domain-containing protein -
  HBA50_RS02050 (HBA50_02050) - 394755..395597 (+) 843 WP_045500706.1 undecaprenyl-diphosphate phosphatase -
  HBA50_RS02055 (HBA50_02055) mecA 395709..396452 (+) 744 WP_005591765.1 adaptor protein MecA Regulator
  HBA50_RS02060 (HBA50_02060) - 396443..397615 (+) 1173 WP_045500708.1 glycosyltransferase family 4 protein -
  HBA50_RS02065 (HBA50_02065) sufC 397699..398471 (+) 773 Protein_396 Fe-S cluster assembly ATPase SufC -
  HBA50_RS02070 (HBA50_02070) sufD 398513..399775 (+) 1263 WP_045500710.1 Fe-S cluster assembly protein SufD -
  HBA50_RS02075 (HBA50_02075) - 399816..401048 (+) 1233 WP_045500712.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28560.10 Da        Isoelectric Point: 3.9226

>NTDB_id=430196 HBA50_RS02055 WP_005591765.1 395709..396452(+) (mecA) [Streptococcus cristatus ATCC 51100]
MEVKQINDSTIKITIQLEDLEEHGMEIADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTRSKI
DKNLNFEDLGNLPDMDELSQMSPDEFLKTLEKNIFEKSKDDLEAVKSLEAAEADQEASVDSSEDREENLDRYVYYILSFT
DLQSAVSFAKTVDYPIDLSELYKYDSAYYLTILVDLEDQPALYPAWLLAKMREFAEDTDITRSVLQEHGRLLLVTEAIQQ
LQKVECV

Nucleotide


Download         Length: 744 bp        

>NTDB_id=430196 HBA50_RS02055 WP_005591765.1 395709..396452(+) (mecA) [Streptococcus cristatus ATCC 51100]
ATGGAAGTGAAACAGATTAATGATTCGACGATTAAAATCACCATCCAGTTGGAAGATTTGGAAGAACACGGAATGGAAAT
TGCAGATTTCCTAGTTCCCCAAGAAAAAACAGAAGAATTTTTCTATACTATTTTGGATGAGTTGGAAATGCCGGAAAGCT
TTTTAGACAGTGGTATGCTAAGCTTTCGAGTGACGCCTAAGCCAGACAAGCTGGATGTCTTTGTGACGAGATCCAAGATT
GATAAGAATTTGAATTTTGAAGATTTGGGAAATCTACCGGATATGGATGAGCTCAGCCAGATGTCGCCAGATGAATTCTT
AAAGACTTTGGAAAAAAATATCTTTGAAAAGAGTAAGGATGACCTTGAGGCGGTCAAATCTTTAGAAGCAGCAGAGGCTG
ATCAGGAGGCCTCTGTAGATTCTTCAGAAGATAGGGAAGAAAATCTAGACCGTTATGTCTACTATATTTTGTCATTTACT
GATTTGCAGAGTGCAGTTTCTTTCGCCAAAACGGTTGACTATCCAATAGACCTATCAGAACTTTATAAATACGACTCTGC
CTACTATCTGACTATTTTGGTAGATTTGGAAGATCAACCTGCTCTTTATCCAGCTTGGTTACTGGCTAAAATGCGTGAAT
TTGCTGAGGATACAGATATTACACGTTCTGTCCTACAAGAACACGGGCGTCTGCTTTTGGTGACAGAAGCCATCCAACAG
TTGCAGAAAGTTGAATGCGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.984

98.785

0.652
  mecA Streptococcus pneumoniae D39

65.984

98.785

0.652
  mecA Streptococcus pneumoniae R6

65.984

98.785

0.652
  mecA Streptococcus pneumoniae TIGR4

65.574

98.785

0.648
  mecA Streptococcus mutans UA159

49.59

98.785

0.49
  mecA Streptococcus thermophilus LMG 18311

46.988

100

0.474
  mecA Streptococcus thermophilus LMD-9

46.586

100

0.47