Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   G7084_RS02310 Genome accession   NZ_CP049888
Coordinates   428074..429285 (+) Length   403 a.a.
NCBI ID   WP_166009694.1    Uniprot ID   A0A6G8AZ51
Organism   Weissella coleopterorum strain HDW19     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 423074..434285
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G7084_RS02290 (G7084_02290) walK 423173..425035 (+) 1863 WP_166009686.1 cell wall metabolism sensor histidine kinase WalK -
  G7084_RS02295 (G7084_02295) yycH 425025..426353 (+) 1329 WP_166009688.1 two-component system activity regulator YycH -
  G7084_RS02300 (G7084_02300) yycI 426353..427174 (+) 822 WP_166009690.1 two-component system regulatory protein YycI -
  G7084_RS02305 (G7084_02305) - 427199..427999 (+) 801 WP_166009692.1 MBL fold metallo-hydrolase -
  G7084_RS02310 (G7084_02310) htrA 428074..429285 (+) 1212 WP_166009694.1 trypsin-like peptidase domain-containing protein Regulator
  G7084_RS02315 (G7084_02315) - 429550..429951 (-) 402 WP_166009696.1 DUF1934 domain-containing protein -
  G7084_RS02320 (G7084_02320) - 430052..431413 (+) 1362 WP_281346938.1 HD domain-containing protein -
  G7084_RS02325 (G7084_02325) rpoE 431482..432075 (+) 594 WP_166009700.1 DNA-directed RNA polymerase subunit delta -
  G7084_RS02330 (G7084_02330) - 432269..433870 (+) 1602 WP_166009702.1 CTP synthase -

Sequence

Protein


Download         Length: 403 a.a.        Molecular weight: 42119.53 Da        Isoelectric Point: 6.8931

>NTDB_id=428403 G7084_RS02310 WP_166009694.1 428074..429285(+) (htrA) [Weissella coleopterorum strain HDW19]
MKFNRKQTKYFSVPWLIVVLALIAGLGGGVVGALLVQKFSNEIPAAIGGTSKSVKVNDTKVKGTSAATKAFQQTAPAVVS
VINLQQQQSSGWSLFETTSQSDDLKKASEGSGVIYKSSGQSAFIVTNNHVVAGSKALQVLLSDGTKLNATLVGTDKVSDL
AVLKVKNDKIKQVAEFANSNEIQTGESVLAIGSPLGSDYATSVTEGIISATKREVESADDDGNSLGKATVIQTDAAINPG
NSGGALINLSGQVIGINSMKLTNSSSGTSVEGMGFSIPSNTVVNIINQLEKDGKVVRPALGIKMIDLSRISIADQEDVLK
LSNEHRNGVVITNVTGGTPAERAGLKKYDVITKADGEELSDTGDLRGILNAHKVGDTINLTYFREGHENTTEIKLTAKAA
DNS

Nucleotide


Download         Length: 1212 bp        

>NTDB_id=428403 G7084_RS02310 WP_166009694.1 428074..429285(+) (htrA) [Weissella coleopterorum strain HDW19]
ATGAAATTTAATCGGAAACAAACCAAATATTTTTCAGTACCTTGGTTGATTGTTGTTTTAGCACTCATTGCCGGATTAGG
TGGTGGGGTCGTAGGTGCGTTGCTTGTACAAAAATTTTCAAATGAGATTCCCGCGGCAATTGGAGGGACTAGTAAGTCTG
TCAAGGTAAACGACACGAAAGTGAAGGGTACTAGCGCGGCAACCAAGGCCTTCCAACAAACTGCTCCGGCGGTCGTTTCG
GTTATTAATTTGCAACAGCAACAATCATCGGGGTGGAGTTTATTTGAAACCACAAGCCAAAGTGATGATTTAAAAAAGGC
TTCTGAAGGTTCAGGAGTTATTTATAAATCATCCGGTCAATCAGCGTTTATCGTTACTAATAATCATGTGGTCGCTGGTT
CAAAAGCCTTACAAGTACTGCTAAGTGATGGGACGAAATTGAACGCTACTCTTGTTGGAACGGACAAAGTATCGGACTTG
GCGGTGCTAAAAGTGAAGAACGACAAAATTAAGCAAGTGGCTGAGTTTGCTAATTCGAATGAAATTCAAACTGGTGAATC
AGTTTTAGCGATTGGTTCGCCCTTAGGATCTGATTATGCAACATCGGTGACAGAAGGGATTATTTCGGCAACTAAGCGAG
AAGTTGAATCTGCTGATGACGATGGAAATTCATTAGGTAAAGCTACCGTCATTCAGACCGATGCAGCTATTAATCCAGGT
AATTCTGGTGGAGCGCTGATTAATTTAAGTGGGCAAGTAATTGGAATTAATTCAATGAAATTAACCAATTCAAGCAGTGG
AACCAGTGTCGAAGGAATGGGCTTCTCAATTCCGTCAAATACCGTCGTTAATATCATTAATCAATTGGAAAAAGATGGAA
AAGTCGTTCGACCAGCTTTGGGCATTAAGATGATTGATCTGTCTAGAATTTCAATTGCCGACCAAGAAGATGTTTTGAAA
TTGTCTAATGAGCATCGAAATGGCGTGGTAATTACGAATGTAACCGGTGGTACACCGGCTGAACGCGCAGGTTTAAAAAA
ATATGATGTGATTACTAAAGCGGATGGGGAAGAATTGAGTGACACTGGTGATTTACGTGGTATTTTGAACGCTCATAAAG
TCGGCGATACGATCAATCTAACTTATTTCCGTGAAGGACATGAAAATACGACGGAAATTAAGTTAACGGCAAAAGCGGCC
GATAATAGTTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(298-395)

Peptidase family M50 (Peptidase_M50)

(270-398)

Trypsin-like peptidase domain (Trypsin_2)

(110-256)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8AZ51

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

48.139

100

0.481
  htrA Streptococcus gordonii str. Challis substr. CH1

46.231

98.759

0.457
  htrA Streptococcus mitis NCTC 12261

42.821

98.511

0.422
  htrA Streptococcus pneumoniae TIGR4

42.569

98.511

0.419
  htrA Streptococcus pneumoniae D39

42.569

98.511

0.419
  htrA Streptococcus pneumoniae Rx1

42.569

98.511

0.419
  htrA Streptococcus pneumoniae R6

42.569

98.511

0.419