Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   G7081_RS00995 Genome accession   NZ_CP049886
Coordinates   207482..208738 (+) Length   418 a.a.
NCBI ID   WP_166006584.1    Uniprot ID   A0A6G8ALF9
Organism   Vagococcus coleopterorum strain HDW17A     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 202482..213738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G7081_RS00985 (G7081_00985) truA 206045..206782 (-) 738 WP_166006580.1 tRNA pseudouridine(38-40) synthase TruA -
  G7081_RS00990 (G7081_00990) rlmH 206796..207275 (-) 480 WP_166006582.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  G7081_RS00995 (G7081_00995) htrA 207482..208738 (+) 1257 WP_166006584.1 S1C family serine protease Regulator
  G7081_RS01000 (G7081_01000) - 208772..209578 (-) 807 WP_166006586.1 MBL fold metallo-hydrolase -
  G7081_RS01005 (G7081_01005) yycI 209595..210392 (-) 798 WP_166006588.1 two-component system regulatory protein YycI -
  G7081_RS01010 (G7081_01010) - 210392..211690 (-) 1299 WP_238786645.1 YycH family regulatory protein -
  G7081_RS01015 (G7081_01015) walK 211690..213510 (-) 1821 WP_166006592.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44044.67 Da        Isoelectric Point: 4.6626

>NTDB_id=428341 G7081_RS00995 WP_166006584.1 207482..208738(+) (htrA) [Vagococcus coleopterorum strain HDW17A]
MTEIKDVTPNKKKNKNSTSLKRLLVGILGGVIGTALTLGLGYGFLKPVLTDRNPSVPNTAKTDVKKRDYTVIGDVSKAVE
TVQDAVVSVVNLQKKEQLNDFGRFFGEDLVDPNDKDDDALQANSEGSGVIYRKDGGDAYVVTNNHVVEGSDALEVLLNDG
TKVPGELVGHDSYTDLAVIKIASKDVKATAEFGDSDSLKVGEPAIAIGSPLGSVYANSATQGIISAKNREITNQTEKGEP
VSINALQTDAAINPGNSGGPLINIAGQVIGINSIKISAASSGVSAEGMGFSIPSNDVVAIISQLEKDGKVSRPTLGITMS
DLSLITKDSQENILKVPADITTGVIIRSVGAATPAEKAGLQQYDVIVEIDGDAIETGTDLQSLLYKKKVGDKISVTFYRE
AEKKTTTVDLVVEQSREK

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=428341 G7081_RS00995 WP_166006584.1 207482..208738(+) (htrA) [Vagococcus coleopterorum strain HDW17A]
ATGACTGAAATAAAAGATGTAACACCTAACAAAAAGAAAAACAAAAATTCCACTTCTTTAAAACGACTACTAGTTGGTAT
CCTCGGCGGCGTAATCGGAACTGCTTTAACTCTCGGTCTGGGATACGGTTTCTTAAAACCGGTTTTAACAGATCGCAATC
CATCTGTGCCAAATACGGCTAAAACGGATGTGAAAAAACGTGATTATACCGTAATTGGAGATGTATCAAAAGCCGTTGAA
ACAGTTCAAGATGCGGTTGTATCTGTTGTTAATTTACAAAAGAAAGAACAATTAAATGATTTTGGCCGTTTCTTCGGGGA
AGACTTAGTCGATCCTAACGACAAAGATGATGATGCTTTACAAGCTAACAGCGAAGGTAGCGGTGTAATCTATCGTAAAG
ATGGTGGTGATGCTTACGTCGTTACTAACAATCATGTTGTGGAAGGTTCTGACGCGTTAGAAGTTTTATTAAACGATGGG
ACAAAAGTTCCCGGCGAACTTGTCGGTCATGATAGTTATACTGATTTAGCTGTTATTAAAATTGCTAGCAAAGATGTCAA
AGCCACTGCTGAATTTGGTGATTCTGACAGCTTAAAAGTTGGCGAACCAGCAATTGCAATCGGTTCACCACTTGGTTCCG
TTTATGCAAACAGTGCTACTCAAGGTATCATCTCCGCTAAGAATCGTGAAATTACAAATCAAACAGAAAAAGGTGAACCT
GTCAGCATTAATGCTTTACAAACAGATGCTGCCATCAACCCTGGTAACTCTGGTGGTCCACTAATCAATATCGCAGGCCA
AGTAATCGGTATTAACTCAATTAAAATCTCAGCAGCTTCTAGCGGTGTCTCTGCTGAAGGAATGGGCTTCTCAATTCCAA
GTAATGATGTTGTCGCAATCATTAGCCAACTTGAAAAAGATGGTAAAGTATCGCGCCCAACACTTGGTATAACGATGAGT
GACTTATCATTGATCACAAAAGACAGCCAAGAAAATATTCTAAAAGTACCAGCTGATATTACAACTGGTGTGATTATTCG
TAGCGTCGGTGCGGCAACGCCTGCTGAAAAAGCTGGCTTACAACAATATGATGTGATTGTCGAAATAGATGGTGATGCTA
TTGAAACAGGAACTGATTTACAGTCTTTACTGTATAAGAAAAAAGTTGGCGATAAAATCTCAGTTACTTTCTACCGTGAA
GCAGAGAAGAAAACAACAACAGTTGATTTAGTCGTTGAACAATCAAGAGAGAAATAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(6-413)

PDZ domain (PDZ_2)

(313-410)

Trypsin-like peptidase domain (Trypsin_2)

(126-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8ALF9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

51.276

93.78

0.481
  htrA Streptococcus gordonii str. Challis substr. CH1

48.072

93.062

0.447
  htrA Streptococcus mitis NCTC 12261

49.862

86.842

0.433
  htrA Streptococcus pneumoniae TIGR4

52.679

80.383

0.423
  htrA Streptococcus pneumoniae D39

52.679

80.383

0.423
  htrA Streptococcus pneumoniae Rx1

52.679

80.383

0.423
  htrA Streptococcus pneumoniae R6

52.679

80.383

0.423