Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   G6Z52_RS01365 Genome accession   NZ_CP049187
Coordinates   253529..254290 (+) Length   253 a.a.
NCBI ID   WP_002991124.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY1687     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 248529..259290
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G6Z52_RS01350 (G6Z52_01355) - 248787..250355 (-) 1569 WP_002991130.1 ABC transporter substrate-binding protein/permease -
  G6Z52_RS01355 (G6Z52_01360) - 250553..252478 (+) 1926 WP_002991128.1 DUF2207 domain-containing protein -
  G6Z52_RS01360 (G6Z52_01365) - 252544..253383 (+) 840 WP_002991126.1 undecaprenyl-diphosphate phosphatase -
  G6Z52_RS01365 (G6Z52_01370) mecA 253529..254290 (+) 762 WP_002991124.1 adaptor protein MecA Regulator
  G6Z52_RS01370 (G6Z52_01375) - 254297..255466 (+) 1170 WP_002991122.1 MraY family glycosyltransferase -
  G6Z52_RS01375 (G6Z52_01380) sufC 255588..256358 (+) 771 WP_002986023.1 Fe-S cluster assembly ATPase SufC -
  G6Z52_RS01380 (G6Z52_01385) sufD 256453..257715 (+) 1263 WP_002991119.1 Fe-S cluster assembly protein SufD -
  G6Z52_RS01385 (G6Z52_01390) - 257746..258972 (+) 1227 WP_002991117.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29033.69 Da        Isoelectric Point: 4.1622

>NTDB_id=425273 G6Z52_RS01365 WP_002991124.1 253529..254290(+) (mecA) [Streptococcus pyogenes strain TSPY1687]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHITILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=425273 G6Z52_RS01365 WP_002991124.1 253529..254290(+) (mecA) [Streptococcus pyogenes strain TSPY1687]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCCACTCTAGCTAATCAGTCTGAGGCGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATAACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

62.8

98.814

0.621
  mecA Streptococcus thermophilus LMD-9

55.823

98.419

0.549
  mecA Streptococcus thermophilus LMG 18311

55.02

98.419

0.542
  mecA Streptococcus pneumoniae Rx1

48.235

100

0.486
  mecA Streptococcus pneumoniae D39

48.235

100

0.486
  mecA Streptococcus pneumoniae R6

48.235

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.235

100

0.486