Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   G5S31_RS10835 Genome accession   NZ_CP049090
Coordinates   2208444..2209571 (+) Length   375 a.a.
NCBI ID   WP_164689643.1    Uniprot ID   -
Organism   Glaesserella parasuis strain aHPS7     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2190919..2219988 2208444..2209571 within 0


Gene organization within MGE regions


Location: 2190919..2219988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G5S31_RS10715 (G5S31_10675) - 2192343..2192918 (+) 576 WP_075630754.1 Panacea domain-containing protein -
  G5S31_RS10720 (G5S31_10680) - 2192915..2193373 (+) 459 WP_075630753.1 hypothetical protein -
  G5S31_RS10725 (G5S31_10685) - 2193482..2194204 (+) 723 WP_075630752.1 hypothetical protein -
  G5S31_RS10730 (G5S31_10690) - 2194268..2195476 (-) 1209 WP_082259179.1 IS256 family transposase -
  G5S31_RS10735 (G5S31_10695) - 2195754..2195960 (+) 207 WP_164689329.1 helix-turn-helix transcriptional regulator -
  G5S31_RS10740 (G5S31_10700) - 2195977..2196366 (+) 390 WP_160405517.1 hypothetical protein -
  G5S31_RS10745 (G5S31_10705) - 2196350..2196652 (+) 303 WP_160405515.1 hypothetical protein -
  G5S31_RS10750 (G5S31_10710) - 2196642..2197115 (+) 474 WP_160405513.1 hypothetical protein -
  G5S31_RS10755 (G5S31_10715) - 2197103..2197540 (+) 438 WP_234885786.1 terminase small subunit -
  G5S31_RS10760 (G5S31_10720) - 2197595..2197846 (+) 252 Protein_2094 Rha family transcriptional regulator -
  G5S31_RS10765 (G5S31_10725) - 2197861..2198619 (+) 759 WP_005713034.1 phage antirepressor Ant -
  G5S31_RS10770 (G5S31_10730) - 2198667..2199617 (+) 951 WP_160405509.1 host cell division inhibitor Icd-like protein -
  G5S31_RS10775 (G5S31_10735) - 2199610..2199882 (+) 273 WP_078208515.1 hypothetical protein -
  G5S31_RS10780 (G5S31_10740) - 2199875..2200183 (+) 309 WP_164689331.1 hypothetical protein -
  G5S31_RS10785 (G5S31_10745) - 2200176..2200511 (+) 336 WP_075630742.1 hypothetical protein -
  G5S31_RS10790 (G5S31_10750) - 2200508..2200915 (+) 408 WP_075630741.1 hypothetical protein -
  G5S31_RS10795 (G5S31_10755) - 2200899..2203085 (+) 2187 WP_160405507.1 DUF927 domain-containing protein -
  G5S31_RS10800 (G5S31_10760) - 2203707..2203982 (+) 276 WP_075630739.1 type II toxin-antitoxin system RelE family toxin -
  G5S31_RS10805 (G5S31_10765) - 2204021..2204401 (+) 381 WP_075630738.1 helix-turn-helix domain-containing protein -
  G5S31_RS10810 (G5S31_10770) - 2205220..2205717 (-) 498 WP_206337873.1 hypothetical protein -
  G5S31_RS10815 - 2205698..2205841 (-) 144 WP_010787341.1 hypothetical protein -
  G5S31_RS10820 (G5S31_10775) rfaD 2205933..2206859 (-) 927 WP_021110191.1 ADP-glyceromanno-heptose 6-epimerase -
  G5S31_RS10825 (G5S31_10780) def 2206871..2207383 (-) 513 WP_005712670.1 peptide deformylase -
  G5S31_RS10830 (G5S31_10785) - 2207601..2208419 (+) 819 WP_021114360.1 Bro-N domain-containing protein -
  G5S31_RS10835 (G5S31_10790) dprA 2208444..2209571 (+) 1128 WP_164689643.1 DNA-processing protein DprA Machinery gene
  G5S31_RS10840 (G5S31_10795) - 2209624..2210460 (+) 837 WP_160405501.1 heme/hemin ABC transporter substrate-binding protein -
  G5S31_RS10845 (G5S31_10800) - 2210460..2211446 (+) 987 WP_021110188.1 FecCD family ABC transporter permease -
  G5S31_RS10850 (G5S31_10805) - 2211446..2212234 (+) 789 WP_010787335.1 heme ABC transporter ATP-binding protein -
  G5S31_RS10860 (G5S31_10815) - 2212846..2217651 (+) 4806 WP_164689645.1 YadA-like family protein -
  G5S31_RS11950 - 2217715..2217840 (-) 126 WP_021113336.1 hypothetical protein -
  G5S31_RS10865 (G5S31_10820) rpoH 2218081..2219028 (-) 948 WP_005711000.1 RNA polymerase sigma factor RpoH -
  G5S31_RS10870 (G5S31_10825) xerC 2219086..2219988 (-) 903 WP_080513250.1 tyrosine recombinase XerC -

Sequence

Protein


Download         Length: 375 a.a.        Molecular weight: 41739.75 Da        Isoelectric Point: 5.4146

>NTDB_id=424688 G5S31_RS10835 WP_164689643.1 2208444..2209571(+) (dprA) [Glaesserella parasuis strain aHPS7]
MTHLTKLLALLQVPQLGAQRIGRLLSEVDFGEFCQYDKTALKQMGWNERQIQRWFNPEHKWIDQALQWAEQDQQRILTLF
DEDYPFLLKQISTAPPVLFVRGNVESLSLPQIAIVGSRDYSHYGEHWAGHFSAELVKHQLAVTSGLAIGIDGFCHQRAAN
ENGITIAVLGSGLDQVYPARHKKLAEQIVETSGALVSEFFPSQPPIAENFPRRNRIISGLSLGTLVIEATVNSGSLITAR
YALEQGREVFALPNAVQNPYSEGCHKLIKEGALLVENVEDILEAIAWQRQSVHIQPSLFDTKPKQAVKSEPKFAKNLPEL
TACQQQLFEQISLEPISIDDLAKATDMAVETALIELLNLELLGVVKQVSGGYVIT

Nucleotide


Download         Length: 1128 bp        

>NTDB_id=424688 G5S31_RS10835 WP_164689643.1 2208444..2209571(+) (dprA) [Glaesserella parasuis strain aHPS7]
ATGACACATCTCACAAAATTATTAGCCCTGTTACAAGTGCCACAGCTTGGCGCACAACGTATCGGGCGGTTACTCTCGGA
AGTGGACTTTGGCGAATTTTGTCAATATGACAAAACCGCATTAAAGCAAATGGGCTGGAATGAACGGCAAATTCAGCGTT
GGTTTAATCCTGAGCATAAATGGATCGATCAGGCGTTGCAATGGGCGGAACAGGATCAGCAACGGATTTTAACTTTATTT
GACGAAGATTATCCTTTTTTATTGAAGCAGATCAGTACTGCTCCCCCTGTGCTTTTTGTGCGTGGGAATGTTGAAAGTTT
ATCGTTACCGCAGATAGCTATCGTCGGCAGTCGAGATTACTCCCACTATGGCGAACACTGGGCAGGGCATTTTTCGGCGG
AATTAGTGAAACATCAACTTGCTGTCACTAGTGGTTTAGCCATAGGCATAGACGGATTTTGTCATCAGCGTGCGGCCAAT
GAAAACGGGATTACTATTGCGGTTTTAGGCAGTGGTTTAGACCAAGTTTACCCTGCTCGCCACAAAAAACTTGCTGAACA
AATCGTTGAAACAAGCGGTGCGTTAGTGTCGGAATTTTTCCCTAGCCAGCCACCGATTGCTGAGAATTTCCCTAGACGAA
ATCGTATTATCAGCGGATTATCGCTAGGAACATTGGTTATTGAAGCAACAGTGAATAGTGGCTCGCTCATTACTGCCCGT
TATGCGTTAGAGCAAGGGAGAGAAGTCTTTGCATTGCCGAACGCAGTACAAAACCCTTATAGCGAAGGGTGCCATAAATT
GATTAAAGAAGGAGCATTACTGGTTGAAAATGTTGAAGATATTTTAGAAGCGATTGCGTGGCAACGGCAGTCAGTGCATA
TTCAACCAAGTCTATTTGATACGAAACCTAAACAAGCGGTGAAATCCGAACCCAAATTTGCAAAAAATCTACCTGAACTG
ACCGCTTGTCAGCAACAATTGTTTGAACAGATTAGCCTTGAGCCGATCAGCATTGATGATCTTGCCAAAGCGACGGATAT
GGCGGTAGAAACCGCATTGATTGAGCTGCTGAATTTGGAGTTGTTGGGCGTAGTGAAGCAGGTGAGTGGGGGGTATGTAA
TCACTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(313-371)

DNA recombination-mediator protein A (DNA_processg_A)

(69-276)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Glaesserella parasuis strain SC1401

98.933

100

0.989
  dprA Haemophilus influenzae Rd KW20

53.235

90.667

0.483
  dprA Vibrio campbellii strain DS40M4

46.917

99.467

0.467
  dprA Vibrio cholerae strain A1552

44.149

100

0.443
  dprA Legionella pneumophila strain ERS1305867

39.418

100

0.397
  dprA Neisseria gonorrhoeae MS11

42.994

83.733

0.36