Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   G5C67_RS07570 Genome accession   NZ_CP049089
Coordinates   1547464..1548726 (-) Length   420 a.a.
NCBI ID   WP_160413800.1    Uniprot ID   -
Organism   Glaesserella parasuis strain vHPS7     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1542464..1553726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G5C67_RS11655 - 1543268..1543546 (-) 279 WP_414626320.1 hypothetical protein -
  G5C67_RS07545 (G5C67_07510) trxA 1544277..1544591 (-) 315 WP_015940165.1 thioredoxin -
  G5C67_RS07550 (G5C67_07515) - 1544888..1545517 (-) 630 WP_015940164.1 LysE family transporter -
  G5C67_RS07555 (G5C67_07520) - 1545519..1545992 (-) 474 WP_164692163.1 phosphatidylglycerophosphatase A -
  G5C67_RS07560 (G5C67_07525) thiL 1545995..1546963 (-) 969 WP_160413801.1 thiamine-phosphate kinase -
  G5C67_RS07565 (G5C67_07530) nusB 1546972..1547385 (-) 414 WP_021112072.1 transcription antitermination factor NusB -
  G5C67_RS07570 (G5C67_07535) comE 1547464..1548726 (-) 1263 WP_160413800.1 type IV pilus secretin PilQ Machinery gene
  G5C67_RS07575 (G5C67_07540) comD 1548736..1549077 (-) 342 WP_021114623.1 pilus assembly, PilP family protein Machinery gene
  G5C67_RS07580 (G5C67_07545) comC 1549122..1549652 (-) 531 WP_021119496.1 hypothetical protein Machinery gene
  G5C67_RS07585 (G5C67_07550) comB 1549649..1550170 (-) 522 WP_062923926.1 hypothetical protein Machinery gene
  G5C67_RS07590 (G5C67_07555) comA 1550146..1550823 (-) 678 WP_021113429.1 hypothetical protein Machinery gene
  G5C67_RS07595 (G5C67_07560) - 1550977..1553532 (+) 2556 WP_021119495.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46997.84 Da        Isoelectric Point: 7.3676

>NTDB_id=424651 G5C67_RS07570 WP_160413800.1 1547464..1548726(-) (comE) [Glaesserella parasuis strain vHPS7]
MRYLFLLFFATFPVLANQQISLSIRNAPTAEIISYLAEETGKNITISDEIKDTKNFRVEKSHFDEILNSLIKTHQLNLKK
ENGIYYIHQAQEHKQHTTAQLVNALPKLITKTIKLHYSKASEVIESLTKGQGNLLSESGYLHFDDRSNSIIVKDSATSVK
NFTQLIESLDKPTEQIAIEARIVTISSEHLQQLGVRWGLFSPNENHYKLAGNLEGNGLTTNNLNVNFPVNPSASVALQIA
AINSRVLDLELTALESENNIEIIASPRLLTTDKKPASIKQGTEIPYAMYSKKEEITDIEFREAVLGLEVTPHISKQNQIL
LDLAISQNSPNNQINNTMVTIDKQEIKTQVLAKHGETIVLGGIFQHLIAKGEDKVPLLGSIPVIKRLFSQSQDKISKREL
VIFVTPYIVKSEKIGAEKQK

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=424651 G5C67_RS07570 WP_160413800.1 1547464..1548726(-) (comE) [Glaesserella parasuis strain vHPS7]
ATGCGTTATTTATTTCTGCTCTTCTTTGCTACTTTTCCTGTATTAGCAAACCAACAAATTTCACTTTCGATAAGAAATGC
CCCAACGGCAGAGATTATTAGTTATTTGGCGGAGGAAACGGGAAAGAATATTACAATTTCGGATGAAATTAAAGATACAA
AAAATTTCAGAGTAGAAAAAAGCCATTTTGATGAGATATTAAATAGTTTAATCAAAACACATCAATTAAATTTAAAAAAA
GAAAATGGCATTTACTATATTCATCAAGCCCAAGAACATAAACAACATACTACGGCACAATTAGTTAATGCTCTGCCTAA
ATTAATCACCAAAACAATCAAGTTACACTATTCCAAAGCCTCTGAAGTTATAGAGTCTTTAACAAAAGGGCAAGGCAATT
TACTATCAGAAAGTGGTTATCTTCACTTTGATGATCGCAGTAATAGCATTATCGTCAAAGACAGTGCCACCTCAGTTAAA
AACTTTACTCAACTTATCGAAAGCCTAGATAAACCAACGGAACAAATTGCAATTGAAGCCCGAATTGTCACTATCAGCAG
TGAACATTTACAACAACTTGGCGTGCGTTGGGGCTTATTTTCCCCTAACGAAAATCACTACAAATTGGCAGGCAATTTAG
AAGGCAACGGATTAACTACCAACAACTTAAACGTAAATTTTCCAGTAAATCCGTCCGCTTCTGTTGCCTTACAAATTGCT
GCAATCAACAGCCGTGTACTTGATTTAGAACTTACTGCATTAGAAAGCGAAAATAACATAGAGATCATTGCAAGCCCTCG
CTTACTCACAACAGATAAAAAACCAGCGAGTATCAAACAAGGTACAGAAATTCCTTATGCAATGTACAGTAAGAAAGAGG
AAATCACCGATATTGAATTTCGTGAAGCCGTTTTGGGGTTAGAGGTCACGCCACATATTTCTAAACAAAATCAGATTTTG
TTAGACCTCGCTATCAGCCAAAATTCGCCCAATAACCAAATAAATAATACAATGGTGACAATTGATAAACAGGAAATCAA
AACGCAAGTTCTAGCTAAACACGGTGAAACCATCGTATTAGGCGGTATTTTTCAACATCTGATCGCCAAAGGCGAAGATA
AAGTACCGCTGTTAGGCAGTATCCCCGTGATTAAACGCTTATTTAGCCAAAGCCAAGATAAAATCTCTAAACGAGAATTA
GTGATTTTTGTCACGCCTTATATTGTGAAATCTGAAAAAATAGGAGCGGAAAAGCAGAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(110-175)

Bacterial type II and III secretion system protein (Secretin)

(253-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

99.524

100

0.995
  comE Haemophilus influenzae Rd KW20

52.941

100

0.536
  comE Haemophilus influenzae 86-028NP

52

100

0.526
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

38.164

98.571

0.376
  pilQ Vibrio cholerae strain A1552

38.164

98.571

0.376
  pilQ Vibrio campbellii strain DS40M4

37.204

100

0.374