Detailed information NTG0424503

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: ST64987_RS08900
• Genome accession: NZ_CP049053
• Coordinates: 1685992..1687092 (-)
• Length: 366 a.a.
• NCBI ID: WP_120764773.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST64987
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1680992..1692092

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST64987_RS10405 (ST64987_1694)	-	1681317..1681592 (-)	276	WP_011681681.1	hypothetical protein	-
ST64987_RS08860 (ST64987_1695)	-	1681604..1681801 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
ST64987_RS08865 (ST64987_1696)	-	1682050..1683243 (-)	1194	WP_014608740.1	acetate kinase	-
ST64987_RS08870 (ST64987_1697)	comYH	1683299..1684255 (-)	957	WP_011681684.1	class I SAM-dependent methyltransferase	Machinery gene
ST64987_RS08875 (ST64987_1698)	comGG	1684300..1684617 (-)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	-
ST64987_RS08880 (ST64987_1699)	comYF	1684595..1685032 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
ST64987_RS08885 (ST64987_1700)	comGE	1685016..1685309 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
ST64987_RS08890 (ST64987_1701)	comYD	1685281..1685709 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
ST64987_RS08895 (ST64987_1702)	comYC	1685669..1685995 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
ST64987_RS08900 (ST64987_1703)	comYB	1685992..1687092 (-)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
ST64987_RS08905 (ST64987_1704)	comGA/cglA/cilD	1686974..1687915 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
ST64987_RS08910 (ST64987_1705)	-	1687996..1688358 (-)	363	WP_167401603.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41876.03 Da
• Isoelectric Point: 10.1377

>NTDB_id=424503 ST64987_RS08900 WP_120764773.1 1685992..1687092(-) (comYB) [Streptococcus thermophilus strain ST64987]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLYQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=424503 ST64987_RS08900 WP_120764773.1 1685992..1687092(-) (comYB) [Streptococcus thermophilus strain ST64987]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTCATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGTATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413