NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	IFO96_RS20760	Genome accession	NZ_CP062211
Coordinates	4264505..4265629 (-)	Length	374 a.a.
NCBI ID	WP_000228538.1	Uniprot ID	-
Organism	Escherichia coli strain L3Cip3
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 4259505..4270629

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IFO96_RS20730 (IFO96_20730)	yrdA	4261305..4261859 (+)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-
IFO96_RS20735 (IFO96_20735)	yrdB	4261835..4262092 (-)	258	WP_001070563.1	DUF1488 domain-containing protein	-
IFO96_RS20740 (IFO96_20740)	aroE	4262089..4262907 (-)	819	WP_000451211.1	shikimate dehydrogenase	-
IFO96_RS20745 (IFO96_20745)	tsaC	4262912..4263484 (-)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
IFO96_RS20750 (IFO96_20750)	yrdD	4263489..4264031 (-)	543	WP_001129724.1	type I DNA topoisomerase	-
IFO96_RS20755 (IFO96_20755)	smg	4264060..4264533 (-)	474	WP_000460670.1	DUF494 family protein Smg	-
IFO96_RS20760 (IFO96_20760)	dprA	4264505..4265629 (-)	1125	WP_000228538.1	DNA-protecting protein DprA	Machinery gene
IFO96_RS20765 (IFO96_20765)	def	4265759..4266268 (+)	510	WP_000114984.1	peptide deformylase	-
IFO96_RS20770 (IFO96_20770)	fmt	4266283..4267230 (+)	948	WP_000004454.1	methionyl-tRNA formyltransferase	-
IFO96_RS20775 (IFO96_20775)	rsmB	4267276..4268565 (+)	1290	WP_192301318.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
IFO96_RS20780 (IFO96_20780)	trkA	4268587..4269963 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
IFO96_RS20785 (IFO96_20785)	mscL	4270093..4270503 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40955.86 Da Isoelectric Point: 6.3122

                                >NTDB_id=424125 IFO96_RS20760 WP_000228538.1 4264505..4265629(-) (dprA) [Escherichia coli strain L3Cip3]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLQATTDYPGALFVEGELHALHSFQLAIVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=424125 IFO96_RS20760 WP_000228538.1 4264505..4265629(-) (dprA) [Escherichia coli strain L3Cip3]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCAGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCATAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACAAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTTTGCT

TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTAGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	45.135	98.93	0.447
dprA	Vibrio cholerae strain A1552	45.135	98.93	0.447
dprA	Haemophilus influenzae Rd KW20	45.401	90.107	0.409
dprA	Glaesserella parasuis strain SC1401	45.133	90.642	0.409
dprA	Legionella pneumophila strain ERS1305867	44.848	88.235	0.396

Detailed information NTG0424125