Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   IGX36_RS02155 Genome accession   NZ_CP062203
Coordinates   460537..461661 (+) Length   374 a.a.
NCBI ID   WP_000228526.1    Uniprot ID   B7UK09
Organism   Escherichia coli strain K_EC180     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 455537..466661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGX36_RS02130 (IGX36_02130) mscL 455663..456073 (-) 411 WP_042002879.1 large-conductance mechanosensitive channel protein MscL -
  IGX36_RS02135 (IGX36_02135) trkA 456203..457579 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  IGX36_RS02140 (IGX36_02140) rsmB 457601..458890 (-) 1290 WP_063085096.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  IGX36_RS02145 (IGX36_02145) fmt 458936..459883 (-) 948 WP_000004456.1 methionyl-tRNA formyltransferase -
  IGX36_RS02150 (IGX36_02150) def 459898..460407 (-) 510 WP_000114986.1 peptide deformylase -
  IGX36_RS02155 (IGX36_02155) dprA 460537..461661 (+) 1125 WP_000228526.1 DNA-protecting protein DprA Machinery gene
  IGX36_RS02160 (IGX36_02160) smg 461633..462106 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  IGX36_RS02165 (IGX36_02165) yrdD 462135..462677 (+) 543 WP_063085097.1 type I DNA topoisomerase -
  IGX36_RS02170 (IGX36_02170) tsaC 462682..463254 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  IGX36_RS02175 (IGX36_02175) aroE 463259..464077 (+) 819 WP_063085098.1 shikimate dehydrogenase -
  IGX36_RS02180 (IGX36_02180) yrdB 464074..464331 (+) 258 WP_001521433.1 DUF1488 domain-containing protein -
  IGX36_RS02185 (IGX36_02185) yrdA 464307..464861 (-) 555 WP_063118525.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40992.90 Da        Isoelectric Point: 6.2662

>NTDB_id=423914 IGX36_RS02155 WP_000228526.1 460537..461661(+) (dprA) [Escherichia coli strain K_EC180]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=423914 IGX36_RS02155 WP_000228526.1 460537..461661(+) (dprA) [Escherichia coli strain K_EC180]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7UK09

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

48.71

82.888

0.404
  dprA Vibrio cholerae strain A1552

48.71

82.888

0.404
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

43.917

90.107

0.396
  dprA Legionella pneumophila strain ERS1305867

43.363

90.642

0.393