Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   G3T13_RS08110 Genome accession   NZ_CP048686
Coordinates   1676104..1677351 (+) Length   415 a.a.
NCBI ID   WP_061775124.1    Uniprot ID   -
Organism   Lactococcus raffinolactis strain KACC 13441     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1671104..1682351
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G3T13_RS08080 - 1671269..1671676 (+) 408 Protein_1592 transposase -
  G3T13_RS08085 - 1671809..1671955 (-) 147 Protein_1593 CAT RNA binding domain-containing protein -
  G3T13_RS08090 guaB 1672229..1673710 (-) 1482 WP_061775120.1 IMP dehydrogenase -
  G3T13_RS08095 - 1673930..1674607 (-) 678 WP_061775121.1 YoaK family protein -
  G3T13_RS08100 - 1674672..1675334 (-) 663 WP_061775122.1 DNA alkylation repair protein -
  G3T13_RS08105 rlmH 1675331..1675807 (-) 477 WP_061775123.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  G3T13_RS08110 htrA 1676104..1677351 (+) 1248 WP_061775124.1 S1C family serine protease Regulator
  G3T13_RS08115 - 1677392..1677643 (-) 252 WP_061775125.1 hypothetical protein -
  G3T13_RS08125 - 1678051..1679049 (+) 999 WP_061775126.1 glycosyltransferase -
  G3T13_RS08130 - 1679149..1680480 (+) 1332 WP_061775127.1 glycosyltransferase family 4 protein -
  G3T13_RS08135 - 1680541..1680765 (+) 225 WP_061775128.1 DUF1797 family protein -
  G3T13_RS08140 - 1680826..1681116 (-) 291 WP_061775129.1 GIY-YIG nuclease family protein -
  G3T13_RS08145 - 1681109..1681855 (-) 747 WP_061775130.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43463.81 Da        Isoelectric Point: 5.3584

>NTDB_id=422293 G3T13_RS08110 WP_061775124.1 1676104..1677351(+) (htrA) [Lactococcus raffinolactis strain KACC 13441]
MKNSKKTAVKLIAAGIIGGAVSLGGNIAYDHFTGDTPIKTNQTSTTKVSDVSYKVSSSTTKAIAKVSDAVVSVINYQKAS
SSNSLDDLFGDSSSTNKDNAKEQPAGEGSGVIYKKDGDYAYIVTNNHVVDGASSLEIMLSNGNKVKGTLVGKDAYSDLAV
IKIPSKEVTKVAEFGDSSKLTVGEPAIAIGSPLGSEYANSATEGIISSLSRKVIMQNESNETVNVNAIQTDAAINPGNSG
GALINVEGQVIGINSSKISATGSSSRDVSVEGMGFAIPSNDVVEIISKLEKDGEIKRPALGVQMVDLTGINSRYIDELKL
PDSVTVGVVVAKVQKGLPADTAGLKKYDVITKIGDTKVTTSTELQSALYKYNVGDEMKVTYYREGKEKTATVKLATSSDK
LDFKDAESAKAEQDK

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=422293 G3T13_RS08110 WP_061775124.1 1676104..1677351(+) (htrA) [Lactococcus raffinolactis strain KACC 13441]
ATGAAAAATAGTAAAAAAACTGCTGTAAAATTAATCGCTGCTGGGATTATCGGTGGTGCTGTTTCATTAGGTGGTAATAT
CGCCTACGACCATTTTACGGGTGATACGCCTATCAAGACGAATCAAACCAGCACGACCAAAGTGTCTGATGTTTCTTATA
AAGTATCAAGTAGTACAACTAAGGCGATTGCCAAAGTATCTGATGCCGTTGTCTCTGTCATTAATTATCAAAAAGCGTCG
TCAAGCAACTCATTAGATGATCTTTTTGGTGATAGCTCATCTACTAATAAGGATAATGCTAAAGAACAACCCGCAGGTGA
AGGCTCTGGTGTAATCTATAAAAAAGACGGTGATTACGCTTATATCGTTACCAACAACCACGTCGTTGATGGTGCAAGCT
CACTAGAAATCATGCTATCAAATGGTAATAAGGTCAAAGGTACTTTAGTCGGGAAAGATGCTTATAGCGATTTAGCGGTC
ATTAAAATTCCATCTAAAGAAGTCACAAAAGTTGCTGAATTCGGCGATTCTTCCAAGCTTACTGTTGGAGAGCCCGCCAT
TGCTATCGGCTCTCCTCTAGGAAGTGAATATGCTAACTCAGCCACTGAAGGGATTATCTCTAGTCTATCACGCAAGGTTA
TCATGCAAAATGAAAGCAATGAAACCGTCAATGTTAATGCCATTCAAACCGATGCCGCGATTAATCCCGGCAACTCTGGT
GGTGCTTTGATCAACGTCGAAGGTCAAGTCATCGGCATCAACTCAAGCAAGATCTCTGCAACAGGTTCATCTTCAAGAGA
TGTTTCTGTTGAAGGGATGGGCTTCGCCATTCCATCCAATGATGTCGTTGAAATTATCAGTAAACTCGAAAAAGACGGTG
AAATCAAGCGCCCAGCACTCGGCGTGCAAATGGTTGATCTCACTGGCATTAACTCGCGCTATATCGACGAGCTCAAACTT
CCTGACTCTGTCACAGTAGGTGTCGTGGTCGCCAAAGTTCAAAAAGGTCTACCAGCCGACACTGCGGGACTTAAAAAATA
TGATGTGATCACGAAAATTGGTGATACTAAAGTGACAACTAGTACTGAACTTCAAAGCGCGCTTTACAAATACAATGTCG
GAGACGAGATGAAAGTCACTTACTACCGTGAGGGTAAAGAAAAAACAGCAACTGTTAAACTTGCTACATCCTCTGATAAG
TTAGACTTTAAAGATGCTGAGTCTGCCAAGGCTGAACAAGATAAATAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(254-397)

Trypsin-like peptidase domain (Trypsin_2)

(108-253)

PDZ domain (PDZ_2)

(298-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

56.127

98.313

0.552
  htrA Streptococcus mutans UA159

57.979

90.602

0.525
  htrA Streptococcus mitis NCTC 12261

51.99

96.867

0.504
  htrA Streptococcus pneumoniae Rx1

55.493

85.542

0.475
  htrA Streptococcus pneumoniae D39

55.493

85.542

0.475
  htrA Streptococcus pneumoniae R6

55.493

85.542

0.475
  htrA Streptococcus pneumoniae TIGR4

55.493

85.542

0.475

Multiple sequence alignment