Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LCGT_RS09270 Genome accession   NC_015930
Coordinates   1823905..1825122 (+) Length   405 a.a.
NCBI ID   WP_014025470.1    Uniprot ID   -
Organism   Lactococcus garvieae ATCC 49156     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1818905..1830122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LCGT_RS09240 (LCGT_1831) eeP 1818916..1820163 (-) 1248 WP_014025467.1 RIP metalloprotease RseP Regulator
  LCGT_RS09245 (LCGT_1832) - 1820339..1821133 (-) 795 WP_003133509.1 phosphatidate cytidylyltransferase -
  LCGT_RS09250 (LCGT_1833) - 1821130..1821867 (-) 738 WP_003133511.1 isoprenyl transferase -
  LCGT_RS09255 (LCGT_1834) yajC 1822068..1822403 (-) 336 WP_014025468.1 preprotein translocase subunit YajC -
  LCGT_RS09260 (LCGT_1835) - 1822478..1823125 (-) 648 WP_014025469.1 DNA alkylation repair protein -
  LCGT_RS09265 (LCGT_1836) rlmH 1823122..1823601 (-) 480 WP_003133515.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LCGT_RS09270 (LCGT_1837) htrA 1823905..1825122 (+) 1218 WP_014025470.1 S1C family serine protease Regulator
  LCGT_RS09275 (LCGT_1838) - 1825220..1826218 (+) 999 WP_014025471.1 glycosyltransferase -
  LCGT_RS09280 (LCGT_1839) - 1826231..1827565 (+) 1335 WP_014025472.1 glycosyltransferase family 4 protein -
  LCGT_RS09285 (LCGT_1840) - 1827616..1827840 (+) 225 WP_003133519.1 DUF1797 family protein -
  LCGT_RS09290 (LCGT_1841) - 1827865..1828914 (-) 1050 WP_014025473.1 BMP family lipoprotein -
  LCGT_RS09300 (LCGT_1842) - 1829074..1829823 (-) 750 WP_014025474.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41786.65 Da        Isoelectric Point: 5.0064

>NTDB_id=42117 LCGT_RS09270 WP_014025470.1 1823905..1825122(+) (htrA) [Lactococcus garvieae ATCC 49156]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNDSNTPQLAGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVKETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSGSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
NVTNGVAIAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRNGKQATANIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=42117 LCGT_RS09270 WP_014025470.1 1823905..1825122(+) (htrA) [Lactococcus garvieae ATCC 49156]
ATGGCAAAGAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGTGGTAGTGCTATCTA
CCAAAACATGACCAATACACCATCATCTAATAACACTTCGGACAATTCTGTAAGTACGGTTAACGTCCAAGTCAATACAG
ATACCACCAAAGCAATCAAGAAAATTTCGAACACTGTTGTTTCCGTTCTTAATTACCAAAAATCGTCCTCAAGCAACGAT
TTTGAGAAGATTTTCGGTGGAGGCGATACAAGCAGCAATGACAGTAACACGCCCCAGCTGGCTGGTGAAGGTTCTGGTGT
TATTTATAAAAAAGATGGCAATACAGCATACATCGTCACCAACTATCACGTGATTGAAGGTGCTTCTTCCTTAGAAGTTC
TCATGGCTGGCGGTCAAAAAGTTACTGCTGAAGTTGTTGGTTCTGATGCTTATTCTGATTTAGCTGTCCTCAAAATTGAT
GCTAAGTATGTCAAAGAAACAGCAACATTCGGTAACTCTGACAAACTTACTGTTGGTGAGCCCGCTATCGCGGTTGGTTC
TCCTCTTGGAAGTGAGTATGCCAACTCAGCAACGGAAGGGATTGTTTCAAGTCTTAATCGTAATGTTACGCTGCAAAACA
GCCAAGGCCAAACAATTAATGTGAACGCAATTCAAACCGATGCAGCAATTAACCCAGGTAACTCTGGTGGTGCACTCATA
AATATTCAGGGACAAGTCATCGGGATTACTTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCGGCAGTGGTGTCTC
TGTAGAAGGAATGGGCTTTGCGATACCAGCCAATGATGTGGTCAATATTATCAATAAGTTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTCGGTGTACAAATGGTCAACTTGTCAAGTCTTTCACAAAATATGTTGGCTTCACTTAATCTTCCTGAA
AATGTGACAAATGGTGTTGCTATCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGTGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTGTGAACCTTCAAAGTACACTTTATAAGTCATCGATTGGTGATA
CGATTAAGGTAACTTATTATCGTAACGGAAAACAAGCTACTGCGAATATCAAGTTGGATAAGACAAGTAGTGACATCAAC
TTTGACAAACAAAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-392)

Peptidase family M50 (Peptidase_M50)

(294-396)

Trypsin-like peptidase domain (Trypsin_2)

(104-249)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

53.885

98.519

0.531
  htrA Streptococcus pneumoniae Rx1

53.634

98.519

0.528
  htrA Streptococcus pneumoniae D39

53.634

98.519

0.528
  htrA Streptococcus pneumoniae R6

53.634

98.519

0.528
  htrA Streptococcus pneumoniae TIGR4

53.634

98.519

0.528
  htrA Streptococcus mutans UA159

56.085

93.333

0.523
  htrA Streptococcus gordonii str. Challis substr. CH1

53.964

96.543

0.521

Multiple sequence alignment