Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SPPN_RS08720 Genome accession   NC_015875
Coordinates   1698488..1700641 (+) Length   717 a.a.
NCBI ID   WP_000205164.1    Uniprot ID   -
Organism   Streptococcus pseudopneumoniae IS7493     
Function   transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1681722..1697546 1698488..1700641 flank 942


Gene organization within MGE regions


Location: 1681722..1700641
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS08610 (SPPN_08715) dcm 1681722..1682987 (+) 1266 WP_000865859.1 DNA (cytosine-5-)-methyltransferase -
  SPPN_RS14030 - 1683051..1683431 (-) 381 Protein_1736 DpnD/PcfM family protein -
  SPPN_RS12970 - 1683427..1684189 (-) 763 Protein_1737 DpnI domain-containing protein -
  SPPN_RS14035 - 1684329..1684667 (-) 339 Protein_1738 hypothetical protein -
  SPPN_RS14220 (SPPN_08750) - 1684767..1684898 (-) 132 WP_259390853.1 hypothetical protein -
  SPPN_RS08625 (SPPN_08755) rbfA 1684924..1685274 (-) 351 WP_001273605.1 30S ribosome-binding factor RbfA -
  SPPN_RS08630 (SPPN_08760) infB 1685440..1688241 (-) 2802 WP_000039199.1 translation initiation factor IF-2 -
  SPPN_RS08635 (SPPN_08765) - 1688258..1688557 (-) 300 WP_001041390.1 YlxQ-related RNA-binding protein -
  SPPN_RS08640 (SPPN_08770) rnpM 1688550..1688843 (-) 294 WP_000857562.1 RNase P modulator RnpM -
  SPPN_RS08645 (SPPN_08775) nusA 1688865..1690001 (-) 1137 WP_000032273.1 transcription termination factor NusA -
  SPPN_RS08650 (SPPN_08780) rimP 1690045..1690524 (-) 480 WP_001808691.1 ribosome maturation factor RimP -
  SPPN_RS08655 (SPPN_08785) trmB 1690650..1691285 (-) 636 WP_001266102.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  SPPN_RS08660 (SPPN_08790) ccrZ 1691282..1692076 (-) 795 WP_000363006.1 cell cycle regulator CcrZ -
  SPPN_RS08665 - 1692238..1692836 (-) 599 Protein_1748 CPBP family intramembrane glutamic endopeptidase -
  SPPN_RS08670 (SPPN_08805) blpZ 1692866..1693114 (-) 249 WP_000276507.1 immunity protein BlpZ -
  SPPN_RS08675 (SPPN_08810) - 1693156..1693845 (-) 690 WP_000760553.1 CPBP family intramembrane glutamic endopeptidase -
  SPPN_RS08680 (SPPN_08815) - 1693877..1694110 (-) 234 WP_000379956.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SPPN_RS12320 (SPPN_08820) - 1694322..1694618 (-) 297 WP_420173450.1 hypothetical protein -
  SPPN_RS08690 (SPPN_08830) - 1695017..1695295 (-) 279 WP_000042206.1 hypothetical protein -
  SPPN_RS08695 (SPPN_08835) - 1695465..1696523 (-) 1059 WP_000795768.1 thioredoxin domain-containing protein -
  SPPN_RS08700 - 1696684..1697023 (-) 340 Protein_1755 immunity protein -
  SPPN_RS08705 (SPPN_08850) - 1697328..1697546 (-) 219 WP_000438253.1 hypothetical protein -
  SPPN_RS08710 (SPPN_08855) - 1697552..1697926 (-) 375 WP_000877386.1 hypothetical protein -
  SPPN_RS08715 (SPPN_08860) - 1697978..1698205 (-) 228 WP_000536880.1 Blp family class II bacteriocin -
  SPPN_RS08720 (SPPN_08865) comA/nlmT 1698488..1700641 (+) 2154 WP_000205164.1 peptide cleavage/export ABC transporter BlpA Regulator

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80878.94 Da        Isoelectric Point: 7.9874

>NTDB_id=42014 SPPN_RS08720 WP_000205164.1 1698488..1700641(+) (comA/nlmT) [Streptococcus pseudopneumoniae IS7493]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTRVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVVTYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=42014 SPPN_RS08720 WP_000205164.1 1698488..1700641(+) (comA/nlmT) [Streptococcus pseudopneumoniae IS7493]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCTAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGAACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACTCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTCGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAAAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATCGTTCTCTCAAGTTTATTGGTCACGATTATCAATATAGGTGGTTCTTA
TTATCTCCAAGGAATCTTAGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTCGGTCTGGTTG
TAACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCCAACTCTATTATAGATGCCTTGGCTTCTACCATTCTCTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGAGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCTATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
CATTGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTAGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGTTGATTACCTT
TAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGCTTGAACGAGGTCTATTTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTCAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGACATATTTCTATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATATTTAATGGCTCTATTTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAG
TCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGGACTAACCGTGTCATTGTTCTTGACCAAGGGA
AAATCATTGAAGTGGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(169-438)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-649)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.888

99.721

0.717
  comA Streptococcus mitis NCTC 12261

66.48

99.442

0.661
  comA Streptococcus pneumoniae Rx1

65.919

99.442

0.656
  comA Streptococcus pneumoniae R6

65.919

99.442

0.656
  comA Streptococcus pneumoniae D39

65.919

99.442

0.656
  comA Streptococcus mitis SK321

65.919

99.442

0.656
  comA Streptococcus gordonii str. Challis substr. CH1

65.181

100

0.653
  comA Streptococcus pneumoniae TIGR4

65.638

99.442

0.653

Multiple sequence alignment