Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SPPN_RS06620 Genome accession   NC_015875
Coordinates   1281506..1282243 (-) Length   245 a.a.
NCBI ID   WP_000782675.1    Uniprot ID   A0A0U0D0G5
Organism   Streptococcus pseudopneumoniae IS7493     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1276506..1287243
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS06600 (SPPN_06695) msrB 1277999..1278937 (-) 939 WP_000818203.1 peptide-methionine (R)-S-oxide reductase MsrB -
  SPPN_RS13210 (SPPN_06700) - 1278998..1279120 (-) 123 WP_014017284.1 hypothetical protein -
  SPPN_RS06610 (SPPN_06705) thrB 1279196..1280065 (-) 870 WP_000692401.1 homoserine kinase -
  SPPN_RS06615 (SPPN_06710) - 1280067..1281353 (-) 1287 WP_000216345.1 homoserine dehydrogenase -
  SPPN_RS06620 (SPPN_06715) mecA 1281506..1282243 (-) 738 WP_000782675.1 adaptor protein MecA Regulator
  SPPN_RS06625 (SPPN_06720) - 1282445..1283479 (-) 1035 WP_000461510.1 hypothetical protein -
  SPPN_RS06630 (SPPN_06725) - 1283472..1284941 (-) 1470 WP_000565083.1 O-antigen polysaccharide polymerase Wzy family protein -
  SPPN_RS06635 (SPPN_06730) - 1284957..1285943 (-) 987 WP_000446983.1 glycosyltransferase family 2 protein -
  SPPN_RS06640 (SPPN_06735) - 1285945..1287048 (-) 1104 WP_000225883.1 glycosyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28396.15 Da        Isoelectric Point: 4.0199

>NTDB_id=42004 SPPN_RS06620 WP_000782675.1 1281506..1282243(-) (mecA) [Streptococcus pseudopneumoniae IS7493]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMNHDAVTN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=42004 SPPN_RS06620 WP_000782675.1 1281506..1282243(-) (mecA) [Streptococcus pseudopneumoniae IS7493]
ATGAAAATGAAACAAATTAGTGATACAACTTTGAAAATCACGATGTCTTTAGAGGATTTGATGGATCGTGGCATGGAGAT
TGCTGACTTTCTTGTCCCTCAAGAAAAAACAGAAGAGTTTTTTTATGCTATCTTGGATGAGTTAGAGATGCCTGATAGCT
TTCTAGATACAGGTATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTTGATGTCTTTGTAACCAAATCAAAGATT
GACCAAAATCTAGATTTTGAAGATTTATCGGATTTACCAGATATGGAAGAATTGGCTCAAATGTCGCCAGATGAGTTTAT
TAAAACCTTAGAAAAGAGCATCGCAGACAAAACTAAGGATGATATCGAAGCGATTCAATCTTTAGAGCAAGTCGAAGCCA
AGGAAGAAGAGCAGGAGCAGGCTGAACAAGAAGCTGAGAGTAAGAAAGAACCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTGGCTTTTGCTAAGACAGTGACTTTTGAGATGGAAACTTCTGAACTCTACAAGATGAATGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGTCCATATCCAGCTTGGCTGTTGGCCCGTATGCGCGAGT
TTGCGGACGATAGTGATATCAGTCGTTCAGTCTTGCAGGAGTATGGCCAAGTCTTGATGAATCACGATGCAGTGACCAAT
CTGCAAAAGATTGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U0D0G5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

98.776

100

0.988
  mecA Streptococcus pneumoniae D39

98.776

100

0.988
  mecA Streptococcus pneumoniae R6

98.776

100

0.988
  mecA Streptococcus pneumoniae TIGR4

98.367

100

0.984
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.486
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.482
  mecA Streptococcus mutans UA159

48.163

100

0.482

Multiple sequence alignment