Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC/blpC   Type   Regulator
Locus tag   IBL27_RS01305 Genome accession   NZ_CP061071
Coordinates   263978..264109 (-) Length   43 a.a.
NCBI ID   WP_002268639.1    Uniprot ID   Q9APK6
Organism   Streptococcus mutans B04Sm5     
Function   binding to ComD; induce autophosphorylation of ComD; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 258978..269109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBL27_RS01285 (IBL27_01285) - 259952..260578 (+) 627 WP_002278266.1 hypothetical protein -
  IBL27_RS01290 (IBL27_01290) - 260626..261264 (+) 639 WP_002265117.1 VTT domain-containing protein -
  IBL27_RS01295 (IBL27_01295) comE/blpR 261735..262487 (+) 753 WP_002270252.1 response regulator transcription factor Regulator
  IBL27_RS01300 (IBL27_01300) comD/blpH 262484..263809 (+) 1326 WP_002308983.1 sensor histidine kinase Regulator
  IBL27_RS01305 (IBL27_01305) comC/blpC 263978..264109 (-) 132 WP_002268639.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  IBL27_RS01310 (IBL27_01310) cipB 264376..264606 (+) 231 WP_002309764.1 Blp family class II bacteriocin Regulator
  IBL27_RS01315 (IBL27_01315) - 264737..265138 (+) 402 WP_002310604.1 hypothetical protein -
  IBL27_RS01320 (IBL27_01320) - 266518..266937 (+) 420 WP_002263913.1 hypothetical protein -
  IBL27_RS01325 (IBL27_01325) - 267084..267488 (+) 405 WP_002263912.1 hypothetical protein -
  IBL27_RS09845 - 267611..267823 (-) 213 Protein_238 IS3 family transposase -
  IBL27_RS01330 (IBL27_01330) - 268263..268427 (+) 165 WP_002265308.1 hypothetical protein -
  IBL27_RS01335 (IBL27_01335) - 268832..269044 (+) 213 WP_002309424.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 43 a.a.        Molecular weight: 4926.71 Da        Isoelectric Point: 10.1937

>NTDB_id=419757 IBL27_RS01305 WP_002268639.1 263978..264109(-) (comC/blpC) [Streptococcus mutans B04Sm5]
MKKTLSLKNDFKEIKTDELEIIIGGSGTLSTFFRLFNRSFTQA

Nucleotide


Download         Length: 132 bp        

>NTDB_id=419757 IBL27_RS01305 WP_002268639.1 263978..264109(-) (comC/blpC) [Streptococcus mutans B04Sm5]
ATGAAAAAAACACTATCATTAAAAAATGACTTTAAAGAAATTAAAACTGATGAATTAGAGATTATCATTGGCGGAAGCGG
AACCCTGTCAACATTTTTCCGGCTGTTTAACAGAAGTTTTACACAAGCTTAG

Domains

Predicted by InterProScan.

COMC family (ComC)

(1-32)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 2I2H

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/blpC Streptococcus mutans UA159

97.674

100

0.977
  comC/comC1 Streptococcus pneumoniae R6

44.444

83.721

0.372
  comC/comC1 Streptococcus pneumoniae G54

44.444

83.721

0.372
  comC/comC1 Streptococcus pneumoniae D39

44.444

83.721

0.372
  comC/comC1 Streptococcus pneumoniae Rx1

44.444

83.721

0.372