Detailed information NTG0419315

Bioinformatically predicted

Overview

• Name: comGD
• Type: Machinery gene
• Locus tag: IBB93_RS08895
• Genome accession: NZ_CP061022
• Coordinates: 1720119..1720547 (-)
• Length: 142 a.a.
• NCBI ID: WP_011226626.1
• Uniprot ID: Q5M2G1
• Organism: Streptococcus thermophilus strain 24738
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1715119..1725547

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBB93_RS08855 (IBB93_08905)	-	1715256..1715699 (-)	444	WP_011681680.1	hypothetical protein	-
IBB93_RS10380	-	1715773..1716198 (-)	426	WP_014608739.1	CPBP family intramembrane glutamic endopeptidase	-
IBB93_RS10385	-	1716155..1716430 (-)	276	WP_011681681.1	hypothetical protein	-
IBB93_RS08865 (IBB93_08915)	-	1716442..1716639 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
IBB93_RS08870 (IBB93_08920)	-	1716888..1718081 (-)	1194	WP_207567722.1	acetate kinase	-
IBB93_RS08875 (IBB93_08925)	comGH	1718137..1719093 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
IBB93_RS08880 (IBB93_08930)	comGG	1719138..1719455 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	Machinery gene
IBB93_RS08885 (IBB93_08935)	comGF	1719433..1719870 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
IBB93_RS08890 (IBB93_08940)	comGE	1719854..1720147 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	Machinery gene
IBB93_RS08895 (IBB93_08945)	comGD	1720119..1720547 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
IBB93_RS08900 (IBB93_08950)	comGC	1720507..1720833 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
IBB93_RS08905 (IBB93_08955)	comGB	1720830..1721930 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
IBB93_RS08910 (IBB93_08960)	comGA/cglA/cilD	1721812..1722753 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
IBB93_RS08915 (IBB93_08965)	-	1722834..1723196 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 142 a.a.
• Molecular weight: 15859.45 Da
• Isoelectric Point: 10.3330

>NTDB_id=419315 IBB93_RS08895 WP_011226626.1 1720119..1720547(-) (comGD) [Streptococcus thermophilus strain 24738]
MRNMVVKAAQWPIRAFTLLESLMTLAVVVFLTLSLSGSVTGIFQQVEINLFYLRFEYLYRDSQRLASAEGSNVELQLTKD
KVSNGRSSLLIPKSIHLDKGQTLVFDAKGGNSSLTKIRFSSDKEVVTYLLNMGSGKYKKTIS

Nucleotide

• Length: 429 bp

>NTDB_id=419315 IBB93_RS08895 WP_011226626.1 1720119..1720547(-) (comGD) [Streptococcus thermophilus strain 24738]
ATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGCCAATTAGAGCTTTCACCTTGTTGGAGAGCCTGATGACACTAGCAGT
GGTTGTCTTTCTCACTCTGAGTTTGTCAGGCTCAGTCACAGGTATTTTTCAGCAGGTCGAGATTAATCTTTTTTATCTGC
GTTTTGAGTACCTATATCGAGATAGTCAGCGCTTGGCATCAGCGGAAGGATCTAATGTTGAATTGCAGTTAACTAAGGAT
AAGGTTAGTAATGGAAGGTCTAGTCTGCTTATTCCTAAAAGTATTCATCTGGATAAGGGGCAGACGCTAGTGTTTGATGC
TAAAGGAGGCAACTCTAGCCTCACGAAAATTCGTTTTTCAAGTGATAAGGAGGTGGTGACCTATCTGCTTAACATGGGCA
GTGGTAAATATAAAAAGACGATCTCTTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: Q5M2G1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGD	Streptococcus mutans UA140	52.672	92.254	0.486
comGD	Streptococcus mutans UA159	52.672	92.254	0.486
comGD	Streptococcus gordonii str. Challis substr. CH1	41.429	98.592	0.408
comGD/cglD	Streptococcus pneumoniae Rx1	44.094	89.437	0.394
comGD/cglD	Streptococcus pneumoniae D39	44.094	89.437	0.394
comGD/cglD	Streptococcus pneumoniae R6	44.094	89.437	0.394
comGD/cglD	Streptococcus mitis NCTC 12261	44.094	89.437	0.394
comGD/cglD	Streptococcus pneumoniae TIGR4	44.094	89.437	0.394
comGD/cglD	Streptococcus mitis SK321	43.307	89.437	0.387
comGD	Lactococcus lactis subsp. cremoris KW2	40.909	92.958	0.38