Detailed information NTG0041836

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SALIVB_RS07955
• Genome accession: NC_015760
• Coordinates: 1749991..1752231 (-)
• Length: 746 a.a.
• NCBI ID: WP_013991033.1
• Uniprot ID: A0AAP3Q6Q7
• Organism: Streptococcus salivarius CCHSS3
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1744991..1757231

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SALIVB_RS07935 (SALIVB_1656)	-	1745858..1746718 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
SALIVB_RS07940 (SALIVB_1657)	spxR	1746759..1748039 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
SALIVB_RS07945 (SALIVB_1658)	-	1748032..1748577 (-)	546	WP_013991031.1	GNAT family N-acetyltransferase	-
SALIVB_RS07950 (SALIVB_1659)	-	1748643..1749905 (-)	1263	WP_013991032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SALIVB_RS07955 (SALIVB_1660)	comEC/celB	1749991..1752231 (-)	2241	WP_013991033.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SALIVB_RS07960 (SALIVB_1661)	comEA	1752221..1752919 (-)	699	WP_013991034.1	helix-hairpin-helix domain-containing protein	Machinery gene
SALIVB_RS07965 (SALIVB_1662)	-	1753027..1753782 (-)	756	WP_013991035.1	lysophospholipid acyltransferase family protein	-
SALIVB_RS07970 (SALIVB_1663)	-	1753912..1754847 (+)	936	WP_041817390.1	polysaccharide deacetylase family protein	-
SALIVB_RS07975 (SALIVB_1664)	-	1754897..1755661 (+)	765	WP_013991037.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
SALIVB_RS07980 (SALIVB_1665)	-	1755665..1755934 (+)	270	WP_013991038.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84531.46 Da
• Isoelectric Point: 9.8651

>NTDB_id=41836 SALIVB_RS07955 WP_013991033.1 1749991..1752231(-) (comEC/celB) [Streptococcus salivarius CCHSS3]
MWLKKAPINLFSLALLIAALYFTVFVTNVYAIGTFVFLMVCFLKHHWKNKAALKLVGIVGSFFLVYFLFLHHKATIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSPATGQRNFQGFNYQSY
LASQGIYRMAQIERLDYVVSQKSLSPLAFFHQLRRRALVHIQTHFPSPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICMSLVLSLGILPFLTYYYGTFQPVSLILTAIFSIVFDNFLLPVLT
VFFALSGLVIFSQINPLFEWMETFLTWIQSWIGQPLILGKPSLLQFSLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVHTLKAGDKLPMMGSKLQVLYPNKIGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPTLRASVLKAGHHGSKGSSSEAFLDQLHPSLALVSAGENNRYKHPNDETLERFKQRH
IKVLRTDKDGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=41836 SALIVB_RS07955 WP_013991033.1 1749991..1752231(-) (comEC/celB) [Streptococcus salivarius CCHSS3]
ATGTGGCTTAAAAAGGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCTCTTTATTTTACGGTTTTTGTCAC
TAATGTTTATGCTATTGGGACTTTTGTCTTTCTTATGGTCTGTTTTTTGAAACATCATTGGAAGAATAAGGCTGCCCTAA
AGTTGGTGGGAATTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTACACCACAAAGCTACCATACAAGATAAACAA
GCTCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGTTATCGGTTAATGGTGAGCAATTATCAGCTATCGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CGCTGGTATTAAAGGGGAAAATAAAGTTATCCCCAGCAACTGGTCAACGTAATTTTCAAGGGTTCAATTATCAGTCTTAT
CTAGCCAGCCAAGGTATTTATCGAATGGCTCAGATTGAGCGCTTGGATTATGTGGTGTCTCAAAAATCTCTATCTCCCTT
AGCTTTTTTCCATCAATTGAGGAGAAGGGCTTTGGTTCATATCCAGACACATTTTCCTAGTCCTATGAGACACTATATGA
CAGGCCTACTCTTTGGGTATTTGGATAAGGAGTTCGATGAGCAGAGTCAGCTTTACACAAGCCTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTACCTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGATTCAAAGTTTGTTGGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGAATAACCTTACTTCTATTGTTTCTCTTT
TTACCTCATTTTCTTTTAACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCTTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTATGAGCTTGGTATTGAGTCTTGGGATTTTGCCTTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATATTTTCCATAGTCTTTGATAACTTTCTCTTGCCTGTCTTGACG
GTCTTCTTTGCCCTTTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCTTGGATAGGCCAGCCATTAATTTTAGGGAAACCTAGTTTGTTACAGTTTAGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGTTCAAAGGAAAAATGGCAGGAGGGGAGCCAGACGAGCAATG
CAGAGAAAACCTTGATTCCCTATCTACAGGCTAGAGGAGTGTCTCAAATTGATCACCTGGTCCTGACGCATACGGACACA
GACCATATTGGTGATTTGGAAGAAGTGGCCAAGAGGTTTAAGATTAAGGAAATCTGTGTCAGTCAGGGGGCTTTGACTAA
ACCTAGTTTTGTTAAAAGACTTCGGACCTTAAAACGACCAGTTCACACTCTAAAGGCTGGCGACAAATTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGCAGTTTTTTGTTTACTGGTGATTTGGAAAAAGAAGGAGAGGAGGAGCTGATGGCCAGCTATCCAACTTTAAG
GGCAAGCGTCCTCAAAGCTGGACACCACGGTTCAAAAGGCTCATCGTCTGAAGCTTTTTTGGATCAGTTGCACCCCTCCC
TTGCACTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACATTAGAACGTTTTAAGCAACGTCAC
ATTAAGGTTTTACGAACAGATAAAGACGGAGCCATACGTTTTAAGGGTTGGTTTAAATGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-169)

• Competence protein (Competence) (216-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-694)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.529	100	0.487
comEC/celB	Streptococcus mitis NCTC 12261	48.193	100	0.483
comEC/celB	Streptococcus pneumoniae Rx1	46.658	100	0.468
comEC/celB	Streptococcus pneumoniae D39	46.658	100	0.468
comEC/celB	Streptococcus pneumoniae R6	46.658	100	0.468
comEC/celB	Streptococcus pneumoniae TIGR4	46.524	100	0.466
comEC	Lactococcus lactis subsp. cremoris KW2	43.649	99.196	0.433