Detailed information NTG0418323

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: GV831_RS00745
• Genome accession: NZ_CP047891
• Coordinates: 147499..149709 (+)
• Length: 736 a.a.
• NCBI ID: WP_014570695.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain WHH2311
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 142499..154709

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GV831_RS00720 (GV831_00705)	-	143351..143914 (+)	564	WP_004255233.1	GNAT family N-acetyltransferase	-
GV831_RS00725 (GV831_00710)	-	144018..144416 (+)	399	WP_004255236.1	hypothetical protein	-
GV831_RS00730 (GV831_00715)	-	144521..145453 (+)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
GV831_RS00735 (GV831_00720)	-	145450..146811 (+)	1362	WP_004255239.1	ABC transporter permease	-
GV831_RS00740 (GV831_00725)	comEA	146871..147518 (+)	648	WP_004255240.1	ComEA family DNA-binding protein	Machinery gene
GV831_RS00745 (GV831_00730)	comEC	147499..149709 (+)	2211	WP_014570695.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GV831_RS00750 (GV831_00735)	-	149994..150770 (+)	777	WP_004255244.1	alpha/beta hydrolase family protein	-
GV831_RS00755 (GV831_00740)	-	150954..151169 (+)	216	WP_014570694.1	F0F1 ATP synthase subunit C	-
GV831_RS00760 (GV831_00745)	atpB	151214..151927 (+)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
GV831_RS00765 (GV831_00750)	atpF	151942..152448 (+)	507	WP_004255258.1	F0F1 ATP synthase subunit B	-
GV831_RS00770 (GV831_00755)	-	152450..152977 (+)	528	WP_004255262.1	F0F1 ATP synthase subunit delta	-
GV831_RS00775 (GV831_00760)	atpA	153164..154666 (+)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84501.23 Da
• Isoelectric Point: 9.7831

>NTDB_id=418323 GV831_RS00745 WP_014570695.1 147499..149709(+) (comEC) [Lactococcus lactis subsp. lactis strain WHH2311]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKISELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPVYPSITAV
DIGQGDSIFLQDKFNKKTILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKFDVLKVGHHGSKTSSNPDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=418323 GV831_RS00745 WP_014570695.1 147499..149709(+) (comEC) [Lactococcus lactis subsp. lactis strain WHH2311]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTATTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGTCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAAATTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAGTTTACCCCAGTATCACAGCAGTT
GATATTGGCCAAGGGGATAGTATTTTTTTGCAAGATAAATTTAATAAAAAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAATTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Competence protein (Competence) (206-446)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.766	100	0.768
comEC/celB	Streptococcus mitis SK321	44.34	100	0.447
comEC/celB	Streptococcus mitis NCTC 12261	44.205	100	0.446
comEC/celB	Streptococcus pneumoniae TIGR4	43.472	100	0.439
comEC/celB	Streptococcus pneumoniae Rx1	43.069	100	0.435
comEC/celB	Streptococcus pneumoniae D39	43.069	100	0.435
comEC/celB	Streptococcus pneumoniae R6	43.069	100	0.435