Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   M594_RS08015 Genome accession   NZ_CP047883
Coordinates   1645917..1647830 (-) Length   637 a.a.
NCBI ID   WP_153220248.1    Uniprot ID   A0A6M9FDZ9
Organism   Streptococcus mitis strain S022-V3-A4     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1640917..1652830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS07990 (M594_08025) - 1641057..1642022 (+) 966 WP_173876470.1 LacI family DNA-binding transcriptional regulator -
  M594_RS07995 (M594_08030) - 1642059..1643333 (-) 1275 WP_173876471.1 hydroxymethylglutaryl-CoA reductase, degradative -
  M594_RS08000 (M594_08035) - 1643333..1644505 (-) 1173 WP_173876751.1 hydroxymethylglutaryl-CoA synthase -
  M594_RS08005 (M594_08040) - 1644619..1645068 (-) 450 WP_000176931.1 threonine/serine exporter family protein -
  M594_RS08010 (M594_08045) - 1645070..1645828 (-) 759 WP_020903004.1 threonine/serine exporter family protein -
  M594_RS08015 (M594_08050) stkP 1645917..1647830 (-) 1914 WP_153220248.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  M594_RS08020 (M594_08055) - 1647827..1648567 (-) 741 WP_173876472.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  M594_RS08025 (M594_08060) rsmB 1648582..1649895 (-) 1314 WP_173876473.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  M594_RS08030 (M594_08065) fmt 1649888..1650823 (-) 936 WP_173876474.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 637 a.a.        Molecular weight: 69333.91 Da        Isoelectric Point: 9.1567

>NTDB_id=418268 M594_RS08015 WP_153220248.1 1645917..1647830(-) (stkP) [Streptococcus mitis strain S022-V3-A4]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHHPLSNEEAIRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSSLSYNRRNEPKLVFDDATKADTKTLPKVPQSTLTSIPKAPVQEEPPQVK
KVTPQIEEHAPTPKLKKKRKFKARYLILLASVLLVAASLIWIFSRTPATISIPNVAGQTVAEAKEALKKANFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTDVVAELKDKKVPENLIKMEEEESSESEPGTV
LRQTPAAGTTYDLSKASTIVLTVAKKVTSVTMPGYIGSSLEFTKNNLIQIVGVKEANIEVVEVSTAPEGTAEGNVVDQTP
KAGGKIDLASTRIKISIYKPKTPPSSSSSTSVQRGNQGSPTTPNQGNQQGGQQGNQQGTVPTPSQPNSEGNHENSRD

Nucleotide


Download         Length: 1914 bp        

>NTDB_id=418268 M594_RS08015 WP_153220248.1 1645917..1647830(-) (stkP) [Streptococcus mitis strain S022-V3-A4]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGAATTATCAAACAGATTGGTCGAGGGGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATTCTAGACGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACAGATCCGATTG
CTGTGGCGCGTTTCCAGCGGGAAGCGAGAGCCATGGCGGATTTGGACCATCCTCATATCGTTCGGATTACAGATATCGGT
GAAGAAGAGGGACAACAGTATCTCGCAATGGAATATGTTGCTGGATTAGACCTCAAACGCTATATCAAGGAACATCACCC
TCTTTCAAATGAAGAAGCGATTCGAATCATGGGACAAATCCTCTTGGCTATGCGCTTAGCCCATACTCGAGGAATTGTTC
ACAGAGATTTAAAACCGCAAAATATCCTTTTGACACCAGATGGGACTGCCAAGGTTACAGACTTTGGGATTGCAGTAGCC
TTTGCAGAGACGAGTCTAACTCAGACCAACTCAATGCTAGGTTCTGTGCATTATTTATCACCAGAGCAGGCGCGTGGTTC
TAAAGCGACTGTACAGAGCGATATCTATGCCATGGGGATTATTTTCTATGAGATGTTGACTGGCCATATCCCTTACGATG
GGGATAGTGCAGTAACCATCGCCCTCCAGCATTTCCAGAAACCTCTGCCGTCGGTTATAGCTGAAAATCCATCTGTGCCT
CAGGCTTTAGAGAATGTTGTTATTAAGGCAACTGCCAAGAAATTAACAGATCGCTACAAATCAGTTGCTGAGATGTATGT
GGATTTGTCTAGCAGCTTATCTTACAATCGTCGCAATGAACCAAAGTTAGTCTTTGACGATGCGACGAAGGCGGACACCA
AGACTCTTCCTAAAGTTCCACAAAGTACGCTGACTTCTATTCCTAAAGCTCCGGTACAAGAAGAACCTCCTCAAGTGAAG
AAAGTGACTCCGCAGATCGAAGAGCATGCGCCTACGCCAAAATTAAAGAAAAAGCGGAAGTTTAAAGCTCGATATTTGAT
TCTTTTGGCAAGTGTTCTATTAGTAGCTGCTTCTTTGATTTGGATTTTCTCTAGAACACCGGCAACAATTTCCATTCCGA
ATGTGGCCGGACAAACTGTGGCTGAAGCTAAAGAAGCTCTTAAAAAAGCTAATTTCGAAGCAGGCGAAGAAAAATCAGAA
GCTAGTGATACAGTAGCAGAAGGACGTGTTATTCGAACGGATCCAGAAGCTGGTAGCGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGTAAGCAATCTTTCCAATTGAGCAATTACGTCGGACGCAAGTATACGGATGTCGTAGCTG
AACTTAAGGATAAGAAGGTTCCTGAAAATCTCATTAAGATGGAAGAGGAAGAATCTAGCGAAAGTGAACCAGGAACGGTT
CTAAGACAAACACCAGCAGCAGGAACTACGTATGACTTATCAAAGGCTAGTACGATTGTTTTAACAGTTGCTAAAAAGGT
AACTAGTGTAACTATGCCGGGTTATATCGGTTCAAGTCTTGAATTCACTAAAAATAATTTGATTCAAATTGTTGGGGTGA
AAGAGGCTAATATTGAAGTTGTTGAAGTGTCAACCGCTCCTGAAGGAACAGCAGAAGGAAATGTTGTGGATCAGACTCCA
AAAGCGGGTGGAAAAATTGATTTAGCCAGCACACGTATTAAAATTTCGATTTATAAACCCAAAACACCACCATCAAGTTC
CTCTTCAACGTCAGTTCAACGTGGTAACCAAGGTTCACCTACTACTCCAAATCAAGGGAATCAACAAGGTGGCCAGCAAG
GAAATCAACAAGGAACGGTTCCTACTCCGAGTCAACCAAATAGTGAAGGAAACCACGAAAATTCTCGTGATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(372-432)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(441-505)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M9FDZ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

77.133

91.994

0.71
  stkP Streptococcus pneumoniae D39

76.792

91.994

0.706
  stkP Streptococcus pneumoniae R6

76.792

91.994

0.706
  stkP Streptococcus pneumoniae Rx1

76.621

91.994

0.705
  pknB Streptococcus mutans UA159

55.979

90.581

0.507
  stkP/pknB Streptococcus salivarius strain HSISS4

52.534

92.936

0.488

Multiple sequence alignment