Detailed information NTG0418259

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: M594_RS06280
• Genome accession: NZ_CP047883
• Coordinates: 1277738..1278691 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495920.1
• Uniprot ID: A0A081SCJ1
• Organism: Streptococcus mitis strain S022-V3-A4
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1272738..1283691

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M594_RS06260 (M594_06280)	ftsW	1272813..1274036 (-)	1224	WP_173876261.1	cell division peptidoglycan polymerase FtsW	-
M594_RS06265 (M594_06285)	prsA	1274197..1275135 (-)	939	WP_004254642.1	peptidylprolyl isomerase PrsA	-
M594_RS06270 (M594_06290)	-	1275202..1275915 (-)	714	WP_173876262.1	O-methyltransferase	-
M594_RS06275 (M594_06295)	pepF	1275917..1277719 (-)	1803	WP_000244089.1	oligoendopeptidase F	Regulator
M594_RS06280 (M594_06300)	coiA	1277738..1278691 (-)	954	WP_000495920.1	competence protein CoiA	Machinery gene
M594_RS06285 (M594_06305)	tehB	1278764..1279624 (-)	861	WP_173876263.1	SAM-dependent methyltransferase TehB	-
M594_RS06290 (M594_06310)	smpB	1279639..1280106 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
M594_RS06295 (M594_06315)	rnr	1280069..1282423 (-)	2355	WP_173876264.1	ribonuclease R	-
M594_RS06300 (M594_06320)	secG	1282524..1282757 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
M594_RS06305 (M594_06325)	rpmG	1282797..1282946 (-)	150	WP_001809104.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38161.88 Da
• Isoelectric Point: 8.3929

>NTDB_id=418259 M594_RS06280 WP_000495920.1 1277738..1278691(-) (coiA) [Streptococcus mitis strain S022-V3-A4]
MFVARDSRGELVNVLEDKLEKQAYTCPACGGQLRLRQGPSVRIHFAHKTLKDCDFSSENESPEHLENKEVLYHWLKKEAE
VQLEYLLPELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGKKLWLKERLTRLQQGFLYFSQNMGF
YVWELDSEKQVLRLKYLIHQDLRGKLHYQIKEFPYGHGSLLEILRFPYKKQKISHFTVSQDKDICRYIRQQLYYQNPIWM
KEQAEAYKKGENLLTYGLKEWYPQIRPLVGNFCQIEQDLIRYYLYFQTYYQENPQNDWQMLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=418259 M594_RS06280 WP_000495920.1 1277738..1278691(-) (coiA) [Streptococcus mitis strain S022-V3-A4]
ATGTTTGTTGCGAGAGATTCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAGCTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGTCAGCTCCGTTTGCGTCAAGGACCAAGTGTCCGGATCCATTTTGCCCACAAAACCTTAAAAGACTGTG
ATTTTTCCTCTGAAAATGAAAGTCCAGAACATCTGGAAAATAAGGAAGTCCTTTATCACTGGTTGAAAAAAGAGGCCGAG
GTGCAATTAGAATACCTGCTTCCAGAGCTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTTTAGAGGTTCA
ATGTAGTCCCTTGCCTCAAAAAGTTCTTAAAGAGCGTAGCGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGAAAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAACAAGGTTTTCTCTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAGTGAAAAACAAGTTTTAAGACTCAAATACCTGATTCACCAAGATCTCCGAGGTAAACTCCA
TTATCAGATTAAGGAATTTCCCTATGGTCACGGTAGTTTACTGGAGATATTACGTTTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTCAGGACAAGGACATCTGTCGTTATATCCGGCAACAACTGTACTATCAAAATCCCATTTGGATG
AAAGAACAAGCAGAAGCCTATAAAAAGGGAGAAAATCTCCTGACTTATGGGCTAAAAGAATGGTATCCACAAATTCGACC
ACTAGTAGGTAATTTTTGCCAAATTGAGCAAGATTTGATTCGCTATTATCTGTATTTTCAAACCTATTATCAAGAAAATC
CTCAAAATGATTGGCAAATGCTCTATCCACCAGCCTTTTATCAGCAATATTTCTTAAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-256)

3D structure

• AlphaFold DB: A0A081SCJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	100	100	1
coiA	Streptococcus pneumoniae TIGR4	89.274	100	0.893
coiA	Streptococcus pneumoniae Rx1	89.274	100	0.893
coiA	Streptococcus pneumoniae D39	89.274	100	0.893
coiA	Streptococcus pneumoniae R6	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	44.099	100	0.448