Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   M594_RS03660 Genome accession   NZ_CP047883
Coordinates   745010..745750 (+) Length   246 a.a.
NCBI ID   WP_173876737.1    Uniprot ID   A0A6M9F1X7
Organism   Streptococcus mitis strain S022-V3-A4     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 740010..750750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS03650 (M594_03680) - 740768..743359 (+) 2592 WP_173876002.1 MBL fold metallo-hydrolase -
  M594_RS03655 (M594_03685) - 743407..744885 (-) 1479 WP_125452246.1 oligosaccharide flippase family protein -
  M594_RS03660 (M594_03690) mecA 745010..745750 (+) 741 WP_173876737.1 adaptor protein MecA Regulator
  M594_RS03665 (M594_03695) - 745897..747183 (+) 1287 WP_173876003.1 homoserine dehydrogenase -
  M594_RS03670 (M594_03700) thrB 747185..748054 (+) 870 WP_049516101.1 homoserine kinase -
  M594_RS03675 (M594_03705) msrB 748269..749207 (+) 939 WP_173876004.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28510.30 Da        Isoelectric Point: 4.0092

>NTDB_id=418251 M594_RS03660 WP_173876737.1 745010..745750(+) (mecA) [Streptococcus mitis strain S022-V3-A4]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPESFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEEEQAEQEAESKKEPYIYYILSFA
KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMNHDAVLN
LQKIGS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=418251 M594_RS03660 WP_173876737.1 745010..745750(+) (mecA) [Streptococcus mitis strain S022-V3-A4]
ATGAAAATGAAACAAATCAGTGATACAACTTTAAAAATCACGATGTCTTTAGAGGATTTGATGGATCGTGGCATGGAGAT
TGCTGACTTTCTTGTCCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCCATCTTGGATGAGTTAGAGATGCCTGAGAGCT
TTTTGGATACAGGTATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTTGATGTTTTTGTAACCAAATCAAAGATT
GACCAAAATCTAGATTTTGAAGATTTATCAGATTTACCAGACATGGAAGAATTGGCTCAAATGTCGCCAGATGAGTTTAT
TAAAACTTTAGAAAAAAGCATCGCGGACAAAACCAAAGATGATATCGAAGCCATTCAATCTCTAGAGCAAGTTGAAGCCA
AGGAAGAAGAGGAAGAGCAGGCTGAACAAGAAGCTGAAAGCAAGAAAGAGCCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTAGCTTTTGCCAAGACAGTGACTTTTGAGATGGAAACTTCTGAACTCTACAAGATGAACGAGCG
CTATTATTTGACTATTCTAGTGGATATTGAAAATCATCCAAGTCCATATCCAGCTTGGCTGTTGGCCCGTATGCGCGAGT
TTGCGGACGATAGTGACATCAGTCGCTCAGTTTTGCAAGAGTATGGTCAAGTCTTGATGAATCACGATGCAGTGCTCAAT
TTGCAAAAGATTGGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M9F1X7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

98.367

99.593

0.98
  mecA Streptococcus pneumoniae D39

98.367

99.593

0.98
  mecA Streptococcus pneumoniae R6

98.367

99.593

0.98
  mecA Streptococcus pneumoniae TIGR4

97.959

99.593

0.976
  mecA Streptococcus mutans UA159

48.571

99.593

0.484
  mecA Streptococcus thermophilus LMD-9

47.39

100

0.48
  mecA Streptococcus thermophilus LMG 18311

46.988

100

0.476

Multiple sequence alignment