Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   M594_RS02460 Genome accession   NZ_CP047883
Coordinates   468658..469317 (-) Length   219 a.a.
NCBI ID   WP_000564998.1    Uniprot ID   F9H8V9
Organism   Streptococcus mitis strain S022-V3-A4     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 463658..474317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS02430 (M594_02460) - 463785..464351 (+) 567 WP_173875865.1 aminodeoxychorismate/anthranilate synthase component II -
  M594_RS02435 (M594_02465) trpD 464362..465366 (+) 1005 WP_000658706.1 anthranilate phosphoribosyltransferase -
  M594_RS02440 (M594_02470) trpC 465363..466130 (+) 768 WP_173875866.1 indole-3-glycerol phosphate synthase TrpC -
  M594_RS02445 (M594_02475) - 466117..466716 (+) 600 WP_173875867.1 phosphoribosylanthranilate isomerase -
  M594_RS02450 (M594_02480) trpB 466694..467917 (+) 1224 WP_049491302.1 tryptophan synthase subunit beta -
  M594_RS02455 (M594_02485) trpA 467910..468686 (+) 777 WP_084888814.1 tryptophan synthase subunit alpha -
  M594_RS02460 (M594_02490) cclA/cilC 468658..469317 (-) 660 WP_000564998.1 prepilin peptidase Machinery gene
  M594_RS02465 (M594_02495) - 469387..469842 (+) 456 WP_173876732.1 GNAT family N-acetyltransferase -
  M594_RS02470 (M594_02500) - 469891..471036 (-) 1146 WP_173875868.1 low temperature requirement protein A -
  M594_RS02475 (M594_02505) - 471854..473143 (+) 1290 WP_004256070.1 hypothetical protein -
  M594_RS02480 (M594_02510) - 473153..474241 (+) 1089 WP_173875869.1 AI-2E family transporter -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24870.99 Da        Isoelectric Point: 7.9575

>NTDB_id=418246 M594_RS02460 WP_000564998.1 468658..469317(-) (cclA/cilC) [Streptococcus mitis strain S022-V3-A4]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISPASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKAPYPVWYALFELGLG
LLFLSWSWGFLSLGQVILITAGLTLGIYDFRHQEYPLLVWITFHLPLMVYSGWNLVMVFFLVLGILAHFIDIRMGAGDFL
FLASCALVFSATELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=418246 M594_RS02460 WP_000564998.1 468658..469317(-) (cclA/cilC) [Streptococcus mitis strain S022-V3-A4]
ATGATTGATTTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTCCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCGC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGCTCCTTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTATCTTGGTCTTGGGGTTTTCTTTCCTTGGGGCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATAACTTTCCATCTGCCTCTAATGGTCTACTCAGGCTGGA
ATCTGGTCATGGTCTTTTTCCTTGTCCTAGGAATTCTAGCTCATTTTATCGATATCCGTATGGGTGCAGGGGATTTCCTC
TTTCTGGCTTCTTGCGCTCTCGTCTTTAGCGCAACCGAGTTACTCATCTTGATTCAGTTTGCTTCTGCAACAGGAATTCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTGCCTTTCGTGCCTTTCCTCTTACTCGCTGCTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9H8V9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

94.977

100

0.95
  cclA/cilC Streptococcus pneumoniae Rx1

91.781

100

0.918
  cclA/cilC Streptococcus pneumoniae D39

91.781

100

0.918
  cclA/cilC Streptococcus pneumoniae R6

91.781

100

0.918
  cclA/cilC Streptococcus pneumoniae TIGR4

90.868

100

0.909
  cclA/cilC Streptococcus mitis NCTC 12261

88.128

100

0.881

Multiple sequence alignment