Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   M594_RS00100 Genome accession   NZ_CP047883
Coordinates   20498..20734 (+) Length   78 a.a.
NCBI ID   WP_173875631.1    Uniprot ID   A0A6M9EWW3
Organism   Streptococcus mitis strain S022-V3-A4     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 15498..25734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS00100 (M594_00100) comW 20498..20734 (+) 237 WP_173875631.1 sigma(X)-activator ComW Regulator
  M594_RS00105 (M594_00105) - 20965..22251 (+) 1287 WP_001832534.1 adenylosuccinate synthase -
  M594_RS00110 (M594_00110) tadA 22450..22917 (+) 468 WP_001110110.1 tRNA adenosine(34) deaminase TadA -
  M594_RS00120 (M594_00120) - 23104..23547 (+) 444 WP_000701987.1 dUTP diphosphatase -
  M594_RS00125 (M594_00125) - 23507..24064 (+) 558 WP_173875632.1 histidine phosphatase family protein -
  M594_RS00130 (M594_00130) radA 24078..25439 (+) 1362 WP_254597275.1 DNA repair protein RadA Machinery gene

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9866.33 Da        Isoelectric Point: 6.8659

>NTDB_id=418220 M594_RS00100 WP_173875631.1 20498..20734(+) (comW) [Streptococcus mitis strain S022-V3-A4]
MLQKIYEQMADFYRNIEEEYGTFFGDHFDWEHVHFKFLIYYLFRYSIGNYRAFIVYHYRVAYRLYLEKLIMNQGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=418220 M594_RS00100 WP_173875631.1 20498..20734(+) (comW) [Streptococcus mitis strain S022-V3-A4]
ATGTTACAAAAAATTTATGAGCAGATGGCGGATTTTTATAGAAATATTGAAGAAGAGTATGGTACGTTCTTCGGAGATCA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTGATTTATTATCTTTTCCGATATAGCATTGGGAATTATCGGGCTTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGATAATGAATCAGGGATTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M9EWW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

82.051

100

0.821
  comW Streptococcus pneumoniae D39

82.051

100

0.821
  comW Streptococcus pneumoniae R6

82.051

100

0.821
  comW Streptococcus pneumoniae TIGR4

82.051

100

0.821
  comW Streptococcus mitis SK321

80.769

100

0.808
  comW Streptococcus mitis NCTC 12261

80.519

98.718

0.795

Multiple sequence alignment