Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   SALIVB_RS02895 Genome accession   NC_015760
Coordinates   564892..566772 (+) Length   626 a.a.
NCBI ID   WP_013990237.1    Uniprot ID   -
Organism   Streptococcus salivarius CCHSS3     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 559892..571772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVB_RS02880 (SALIVB_0581) fmt 561864..562799 (+) 936 WP_041817194.1 methionyl-tRNA formyltransferase -
  SALIVB_RS02885 (SALIVB_0582) rsmB 562789..564111 (+) 1323 WP_013990235.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SALIVB_RS02890 (SALIVB_0583) - 564155..564892 (+) 738 WP_002886859.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SALIVB_RS02895 (SALIVB_0584) stkP/pknB 564892..566772 (+) 1881 WP_013990237.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SALIVB_RS02900 (SALIVB_0585) - 566918..567676 (+) 759 WP_002884314.1 potassium channel family protein -
  SALIVB_RS02905 (SALIVB_0586) liaF 567840..568538 (+) 699 WP_013990238.1 cell wall-active antibiotics response protein LiaF -
  SALIVB_RS02910 (SALIVB_0587) - 568535..569545 (+) 1011 WP_013990239.1 sensor histidine kinase -
  SALIVB_RS02915 (SALIVB_0588) - 569535..570179 (+) 645 WP_002884791.1 response regulator transcription factor -
  SALIVB_RS02930 (SALIVB_0591) rimM 570871..571389 (+) 519 WP_013990240.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 68128.91 Da        Isoelectric Point: 8.2285

>NTDB_id=41819 SALIVB_RS02895 WP_013990237.1 564892..566772(+) (stkP/pknB) [Streptococcus salivarius CCHSS3]
MIQVGKLFAGRYRILKAIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEILSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENHNVP
QALENVVIRATAKKLDNRYNSTLEMSRDLVTSLYPSHSRDAKVVFDDMTDTKTLPKVTPVPSVSSEKKATAKSSESKQAV
SKQPRKKSTLAKNKKKKKKKSFFSTSLKVFLGLVFIGIIIFAYLVFTNPDSTQVPNVVGQELSTAQTKIEGAGFKVGEVK
EMEDDSVGTGKVIKTDPTAGTTRKEGSSIDIYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEE
GEILSQSPGKNKTFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSST
EVLYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTESTSSSTETPTEATHTDQQ

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=41819 SALIVB_RS02895 WP_013990237.1 564892..566772(+) (stkP/pknB) [Streptococcus salivarius CCHSS3]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAAGCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATCTTGGATAATGAGAAAGTGGCCATTAAGGTGCTTCGTACTAATTATCAAACCGATCAGGTAG
CTGTGGCACGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCCAATATCGTTGCAATCCGAGACATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTACGTGGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATTATGGGAGAGATTCTTTCTGCCATGACTCTTGCCCATCAAAAGGGTATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTAGGGCCAAAGTTACAGACTTCGGGATTGCGGTTGCC
TTTGCAGAGACTAGTCTGACTCAAACCAATTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCGCGTGGATC
TAAAGCAACTATCCAAAGTGATATCTATGCTATGGGTATCATGCTCTTTGAAATGTTGACAGGGCATATTCCATATGATG
GTGATAGTGCAGTTACCATCGCTCTTCAGCATTTCCAAAAACCATTACCATCAATCTTGGCTGAGAATCATAATGTTCCT
CAGGCATTGGAAAATGTGGTTATTCGAGCGACAGCTAAAAAGCTTGATAATCGTTATAACAGTACTTTGGAAATGAGCCG
AGATTTAGTAACTAGCTTATATCCTAGCCATAGCCGTGATGCTAAGGTAGTCTTTGATGACATGACGGATACTAAGACTT
TGCCTAAGGTTACTCCAGTTCCGTCAGTAAGCTCTGAGAAAAAGGCAACTGCCAAGTCATCAGAGTCAAAACAAGCTGTA
AGTAAGCAACCAAGGAAAAAGTCAACATTAGCTAAGAATAAAAAGAAGAAAAAAAAGAAAAGCTTTTTCTCGACATCACT
CAAGGTATTCCTGGGGTTGGTCTTTATCGGGATTATCATTTTTGCCTATTTGGTATTTACCAACCCTGATAGTACTCAGG
TGCCTAACGTGGTCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTTAAG
GAAATGGAAGATGACTCTGTCGGTACAGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACCACACGAAAAGAAGGATC
AAGTATTGATATCTATGTTTCTTCTGGTAGTAAAGGTTTCGCGTTGAAAGACTACAAAGGTAAAAATTATAAGGATGCCA
TTGAGGATTTAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAG
GGAGAAATCCTATCTCAAAGTCCAGGGAAAAACAAGACTTTCAATCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGT
GGCAACTCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGA
GTATCTCAAGTAGTAGCATCGAGTATCATGACTATAATACTGGTGCTAAGTTAGACAAGGATAAGGTTCCTAGCAGTACA
GAGGTCCTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAG
TTCAAGCCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGAAAGCACAAGCTCTAGTA
CTGAAACACCGACAGAGGCTACTCACACAGACCAACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(443-507)

PASTA domain (PASTA)

(513-582)

PASTA domain (PASTA)

(373-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

92.982

100

0.931
  pknB Streptococcus mutans UA159

66.544

86.901

0.578
  stkP Streptococcus pneumoniae TIGR4

51.801

93.131

0.482
  stkP Streptococcus pneumoniae D39

51.63

93.131

0.481
  stkP Streptococcus pneumoniae R6

51.63

93.131

0.481
  stkP Streptococcus pneumoniae Rx1

51.458

93.131

0.479

Multiple sequence alignment