Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SALIVB_RS01595 Genome accession   NC_015760
Coordinates   295576..296265 (+) Length   229 a.a.
NCBI ID   WP_002886589.1    Uniprot ID   -
Organism   Streptococcus salivarius CCHSS3     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 290576..301265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVB_RS01570 (SALIVB_0312) - 290808..291638 (+) 831 WP_013990057.1 energy-coupling factor transporter transmembrane component T family protein -
  SALIVB_RS01575 (SALIVB_0313) - 291728..292399 (-) 672 WP_013990058.1 potassium channel family protein -
  SALIVB_RS01580 (SALIVB_0314) - 292439..293824 (-) 1386 WP_041817185.1 TrkH family potassium uptake protein -
  SALIVB_RS01585 (SALIVB_0315) rsmG 293872..294585 (-) 714 WP_013990060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  SALIVB_RS01590 (SALIVB_0316) - 294884..295420 (+) 537 WP_013990061.1 DUF177 domain-containing protein -
  SALIVB_RS01595 (SALIVB_0317) covR 295576..296265 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  SALIVB_RS01600 (SALIVB_0318) covS 296262..297791 (+) 1530 WP_013990062.1 HAMP domain-containing histidine kinase Regulator
  SALIVB_RS01605 (SALIVB_0319) nrdR 297913..298392 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  SALIVB_RS01610 (SALIVB_0320) - 298389..299564 (+) 1176 WP_013990063.1 DnaD domain protein -
  SALIVB_RS01615 (SALIVB_0321) dnaI 299568..300470 (+) 903 WP_013990064.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26517.51 Da        Isoelectric Point: 4.6354

>NTDB_id=41802 SALIVB_RS01595 WP_002886589.1 295576..296265(+) (covR) [Streptococcus salivarius CCHSS3]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIESAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=41802 SALIVB_RS01595 WP_002886589.1 295576..296265(+) (covR) [Streptococcus salivarius CCHSS3]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAATCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCAATCGAAACAAACGTTGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

99.563

100

0.996
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

46.352

100

0.472
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment