Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   SALIVB_RS01600 Genome accession   NC_015760
Coordinates   296262..297791 (+) Length   509 a.a.
NCBI ID   WP_013990062.1    Uniprot ID   -
Organism   Streptococcus salivarius CCHSS3     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 291262..302791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVB_RS01575 (SALIVB_0313) - 291728..292399 (-) 672 WP_013990058.1 potassium channel family protein -
  SALIVB_RS01580 (SALIVB_0314) - 292439..293824 (-) 1386 WP_041817185.1 TrkH family potassium uptake protein -
  SALIVB_RS01585 (SALIVB_0315) rsmG 293872..294585 (-) 714 WP_013990060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  SALIVB_RS01590 (SALIVB_0316) - 294884..295420 (+) 537 WP_013990061.1 DUF177 domain-containing protein -
  SALIVB_RS01595 (SALIVB_0317) covR 295576..296265 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  SALIVB_RS01600 (SALIVB_0318) covS 296262..297791 (+) 1530 WP_013990062.1 HAMP domain-containing histidine kinase Regulator
  SALIVB_RS01605 (SALIVB_0319) nrdR 297913..298392 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  SALIVB_RS01610 (SALIVB_0320) - 298389..299564 (+) 1176 WP_013990063.1 DnaD domain protein -
  SALIVB_RS01615 (SALIVB_0321) dnaI 299568..300470 (+) 903 WP_013990064.1 primosomal protein DnaI -
  SALIVB_RS01620 (SALIVB_0322) der 300575..301885 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  SALIVB_RS01625 (SALIVB_0323) - 301950..302579 (+) 630 WP_013990065.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58149.63 Da        Isoelectric Point: 5.3949

>NTDB_id=41803 SALIVB_RS01600 WP_013990062.1 296262..297791(+) (covS) [Streptococcus salivarius CCHSS3]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSLFTLVVIFSANTLLLQRERQNVNTTIAKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLVFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERLAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDINHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADRETTIPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=41803 SALIVB_RS01600 WP_013990062.1 296262..297791(+) (covS) [Streptococcus salivarius CCHSS3]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGTTGTTCACTCTGGTTGTTATTTTTTCAGCTAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCGCAAAAGTTGTTACTTACATCGAAAAGGATTGGGATTCGGATGAAGAATTAAGTCCAGAACCGCTCTTA
GCGGCTCTTTATTCGCCTAAAAATATCTATGCATCAATTATTAATGGCGTACTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATATTCAAATCAGTCAGTTTTTGTGTATGACAAAAAAGGAACCTTTATCTTTACTTCTG
AGGAGAATACAGATTCGCCTCCCGGTATGTCCGAGGTAAACAAACTGAAGTCAGTATCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGCTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGGTTTTCTTGTTGATTTTCCTAGAAGTGGGGATGACTGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATTACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGCATGATGGATAAAAT
TCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACGCCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAAGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGGAACTTCCGTGTCTTGCATGAAGATTATCAATTTTATCTCA
ATGATTTCGAAAGTTCAGAGCGTCTAGCACAGATTTATAGTCAGCACTTTGAACAGGCGATCACCATTTTGATTGATAAT
GCGGTCAAGTATTCGCCTGTCAATAAGGAAATACAGGTTACTATTAAAGCATTGGAAGATGAAATGTTGGTACAAGTGCA
AGATAACGGTGAGGGGATTTCAAAAGAAGATATCAATCATATTTTTGAACGTTTCTATCGTTCAGATAAGGCACGTAACC
GTACAACAACTCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTATCAAATTGTGGAAGCTTATCGCTGCCGTATTGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATCGAGAAACGACGATACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

98.428

100

0.984

Multiple sequence alignment