Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   LGMK_RS05970 Genome accession   NC_015734
Coordinates   1212319..1214466 (+) Length   715 a.a.
NCBI ID   WP_013103376.1    Uniprot ID   -
Organism   Leuconostoc sp. C2     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1207319..1219466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LGMK_RS05930 (LGMK_05885) - 1207610..1207993 (-) 384 WP_041762798.1 CrcB family protein -
  LGMK_RS05935 (LGMK_05890) - 1208123..1208374 (+) 252 WP_013103384.1 hypothetical protein -
  LGMK_RS09530 (LGMK_05895) - 1208485..1208598 (-) 114 WP_013103383.1 bacteriocin -
  LGMK_RS05940 (LGMK_05900) - 1208961..1210091 (+) 1131 WP_242822131.1 sensor histidine kinase -
  LGMK_RS05945 (LGMK_05905) - 1210097..1210822 (+) 726 WP_013103381.1 response regulator transcription factor -
  LGMK_RS05950 (LGMK_05910) - 1210989..1211213 (-) 225 WP_013103380.1 hypothetical protein -
  LGMK_RS05960 (LGMK_05920) - 1211600..1211806 (-) 207 WP_013103378.1 hypothetical protein -
  LGMK_RS05965 (LGMK_05925) - 1211830..1212039 (-) 210 WP_242651954.1 Blp family class II bacteriocin -
  LGMK_RS05970 (LGMK_05930) comA 1212319..1214466 (+) 2148 WP_013103376.1 peptide cleavage/export ABC transporter Regulator
  LGMK_RS05975 (LGMK_05935) - 1214485..1215834 (+) 1350 WP_013103375.1 bacteriocin secretion accessory protein -
  LGMK_RS05985 (LGMK_05945) - 1216695..1216988 (-) 294 WP_013103373.1 hypothetical protein -
  LGMK_RS05990 (LGMK_05950) - 1217285..1218883 (+) 1599 WP_013103372.1 APC family permease -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 79896.29 Da        Isoelectric Point: 6.7450

>NTDB_id=41696 LGMK_RS05970 WP_013103376.1 1212319..1214466(+) (comA) [Leuconostoc sp. C2]
MKRFDYISQLEEKDCGVSALAMILKQYGSDVSLASIRERCQTSLTGTTALGLVKAAESFNMDVRPIKADLTLFDMKDLPL
PFIAHVEKNGQYLHYYVVYHVTKNKIMIADPDPTVGKTTMTLQDFSNEWTGVALFMSPSPEYKPVKENKSSIQSFLPIIG
RQKPLIVNIIAASLLITLISIAGSYYMQLVIDAYVPNGQANTLTIVSLGLIATYILQQVLGFTRTYLLTVMGQRLSIEVI
LSYIRHLFELPVNFFATRRTGEIVTRFNDANAIIDAMANTILSLFLDLGITIIVGSVLAVQNIQLFLLSLISFPVYFLIV
YTFMKPFEHLNQEQMASNATLSSSIIEDINGIETIKSLTSEKSSYQKIDREFVDYLKKSFAHQKSEAIQNSIKQATQLII
NVLVLWFGAKLVISNQLSVGQLVTYNALLGYFTEPFQNIINLQTKIQTATVANRRLNEVYLVDSEFKANESQELQKDNSY
DLKIDKVSYQYGYQKPILIDFSLKIAFGEKIALVGVSGSGKSTLAKLLVNFMSPSSGNIQIGSQDITHVHRQNLRRHVTY
LPQNPYIFTGSILDNLTLGAPDGTTQEDILNAVTLADIKNDIESMPQNYQTEISEDGGMSGGQKQRIALARALLSQSPIL
ILDESTSNLDVLTEKKIIDNLLTIKNKTIIFIAHRLTIAEKAQRVILLELGAIAEDGTHNELLTHHAQYYHLVNR

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=41696 LGMK_RS05970 WP_013103376.1 1212319..1214466(+) (comA) [Leuconostoc sp. C2]
ATGAAGAGATTTGATTATATATCACAACTAGAAGAAAAAGATTGTGGTGTATCTGCACTTGCGATGATTTTAAAACAATA
CGGTTCTGATGTTTCCTTAGCAAGTATCCGTGAACGTTGTCAAACATCACTGACAGGAACCACGGCACTCGGTTTAGTGA
AAGCTGCCGAATCATTTAACATGGATGTTCGACCTATTAAAGCCGACCTGACATTATTTGATATGAAAGATTTACCATTA
CCATTTATCGCTCATGTTGAGAAAAACGGACAATATTTGCATTATTATGTTGTGTATCATGTTACTAAAAATAAAATCAT
GATTGCGGATCCAGACCCAACAGTTGGTAAAACAACTATGACGCTGCAGGATTTTTCTAACGAGTGGACCGGTGTCGCAT
TATTCATGTCCCCATCCCCAGAATACAAACCAGTTAAAGAAAATAAAAGCAGCATTCAATCATTTTTACCCATTATTGGT
CGACAAAAACCACTGATTGTTAATATTATTGCGGCGTCTTTATTAATCACATTAATTAGCATTGCTGGTTCATACTACAT
GCAACTTGTTATCGACGCTTATGTCCCCAACGGCCAAGCTAATACCTTAACTATTGTTTCATTAGGGTTGATTGCCACCT
ACATCCTACAACAAGTACTGGGTTTTACTCGAACCTACTTATTAACAGTTATGGGGCAACGTCTATCTATTGAAGTCATA
TTGTCTTATATTCGGCATTTGTTTGAATTACCAGTTAATTTCTTCGCCACACGACGAACTGGTGAAATCGTGACACGTTT
TAATGATGCTAATGCTATCATTGATGCAATGGCTAACACGATTCTTTCTTTATTCTTAGACTTAGGCATTACTATTATCG
TCGGTAGTGTCTTGGCTGTGCAAAACATACAACTGTTCCTACTCTCTTTAATTTCATTTCCAGTATATTTTTTAATTGTT
TACACCTTTATGAAACCCTTTGAACACCTCAATCAAGAACAAATGGCGAGTAACGCAACGTTAAGCTCATCGATTATTGA
AGATATTAATGGTATAGAAACAATCAAATCACTCACAAGTGAAAAGTCTAGTTATCAAAAAATTGATCGAGAATTTGTCG
ATTACTTAAAGAAATCATTTGCACATCAAAAAAGTGAAGCGATTCAAAATAGCATTAAACAAGCGACTCAACTGATTATT
AATGTGCTCGTCCTATGGTTTGGTGCTAAACTAGTTATTTCTAATCAACTTAGTGTGGGTCAATTAGTCACGTATAATGC
CTTATTAGGTTATTTTACCGAACCGTTTCAAAATATCATTAACTTACAAACCAAAATACAAACAGCAACTGTTGCAAATC
GGCGATTGAATGAAGTGTACTTAGTGGATTCAGAATTTAAAGCGAACGAATCACAAGAATTACAAAAAGATAATTCATAT
GACCTCAAAATAGACAAAGTCAGCTATCAATATGGTTATCAGAAACCTATTCTAATAGACTTTTCTCTTAAAATAGCTTT
TGGTGAAAAAATAGCCCTTGTAGGTGTTAGTGGATCAGGAAAATCAACACTTGCCAAACTGTTAGTTAACTTCATGTCAC
CATCTAGCGGAAACATTCAAATTGGTTCCCAAGACATTACTCACGTTCATCGTCAAAATCTCAGGCGACATGTGACCTAT
TTACCCCAAAATCCTTATATATTTACTGGCAGCATCTTGGATAATCTCACGCTTGGTGCCCCTGACGGTACAACACAAGA
AGATATTTTAAATGCTGTGACATTAGCGGATATCAAAAACGATATTGAAAGTATGCCTCAGAACTATCAAACTGAAATTT
CAGAAGATGGCGGCATGTCTGGTGGTCAAAAGCAACGCATTGCTTTAGCTCGTGCGCTTTTAAGTCAATCCCCTATTCTC
ATTTTGGATGAATCAACTAGTAATCTCGACGTATTGACTGAGAAAAAAATAATCGATAACTTACTCACTATTAAAAATAA
GACAATTATATTCATCGCTCACCGACTGACTATTGCTGAAAAAGCACAACGCGTTATTTTACTTGAATTAGGTGCTATTG
CTGAAGATGGTACTCACAACGAGCTGCTTACCCATCACGCACAATATTATCATTTAGTTAATCGCTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(4-140)

ABC transporter transmembrane region (ABC_membrane)

(168-436)

ABC transporter (ABC_tran)

(500-647)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

58.078

100

0.583
  comA Streptococcus mitis NCTC 12261

57.746

99.301

0.573
  comA Streptococcus mitis SK321

57.324

99.301

0.569
  comA Streptococcus pneumoniae R6

57.183

99.301

0.568
  comA Streptococcus pneumoniae Rx1

57.183

99.301

0.568
  comA Streptococcus pneumoniae D39

57.183

99.301

0.568
  comA Streptococcus pneumoniae TIGR4

57.042

99.301

0.566
  comA/nlmT Streptococcus mutans UA159

54.469

100

0.545

Multiple sequence alignment