Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   E3S73_RS05435 Genome accession   NZ_CP047799
Coordinates   1071572..1072141 (+) Length   189 a.a.
NCBI ID   WP_123090070.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UP_322     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1066572..1077141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S73_RS05400 (E3S73_05400) - 1068154..1068426 (-) 273 WP_001794574.1 lactococcin 972 family bacteriocin -
  E3S73_RS05405 (E3S73_05405) - 1068436..1068537 (-) 102 WP_001790623.1 hypothetical protein -
  E3S73_RS14225 (E3S73_05410) - 1068707..1068784 (-) 78 WP_099119695.1 putative holin-like toxin -
  E3S73_RS05415 (E3S73_05415) - 1069085..1069687 (-) 603 WP_001033867.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  E3S73_RS05420 (E3S73_05420) - 1069702..1069878 (-) 177 WP_000214898.1 YkvS family protein -
  E3S73_RS05425 (E3S73_05425) - 1070077..1071063 (+) 987 WP_000668820.1 lipoate--protein ligase -
  E3S73_RS05430 (E3S73_05430) - 1071144..1071362 (-) 219 WP_000876825.1 IDEAL domain-containing protein -
  E3S73_RS05435 (E3S73_05435) comK/comK1 1071572..1072141 (+) 570 WP_123090070.1 competence protein ComK Regulator
  E3S73_RS05450 (E3S73_05450) - 1072630..1074141 (-) 1512 WP_000414169.1 bifunctional metallophosphatase/5'-nucleotidase -
  E3S73_RS05455 (E3S73_05455) - 1074280..1075638 (-) 1359 WP_000021872.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22597.84 Da        Isoelectric Point: 9.6091

>NTDB_id=416675 E3S73_RS05435 WP_123090070.1 1071572..1072141(+) (comK/comK1) [Staphylococcus aureus strain UP_322]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKPRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=416675 E3S73_RS05435 WP_123090070.1 1071572..1072141(+) (comK/comK1) [Staphylococcus aureus strain UP_322]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
TGGTAGTGAAATAATTCGGTTTGACAAACCGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCACCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

99.471

100

0.995
  comK/comK1 Staphylococcus aureus N315

99.471

100

0.995

Multiple sequence alignment