Detailed information NTG0416532

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: H7786_RS02420
• Genome accession: NZ_CP060649
• Coordinates: 461788..463941 (-)
• Length: 717 a.a.
• NCBI ID: WP_228646639.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY270
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 456788..468941

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7786_RS02400 (H7786_02435)	comE/blpR	457979..458728 (+)	750	WP_030126108.1	response regulator transcription factor	Regulator
H7786_RS02405 (H7786_02440)	-	458729..460063 (+)	1335	WP_030126107.1	sensor histidine kinase	-
H7786_RS02410 (H7786_02445)	-	460211..460336 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
H7786_RS02415 (H7786_02450)	-	460413..461777 (-)	1365	WP_014635340.1	bacteriocin secretion accessory protein	-
H7786_RS02420 (H7786_02455)	comA/nlmT	461788..463941 (-)	2154	WP_228646639.1	peptide cleavage/export ABC transporter	Regulator
H7786_RS02425 (H7786_02460)	-	464224..464448 (+)	225	WP_030126106.1	Blp family class II bacteriocin	-
H7786_RS02430 (H7786_02465)	-	464525..464743 (+)	219	WP_030126105.1	bacteriocin	-
H7786_RS02435 (H7786_02470)	-	465269..465670 (+)	402	WP_023605036.1	hypothetical protein	-
H7786_RS02440 (H7786_02475)	-	465921..466991 (+)	1071	WP_030126103.1	hypothetical protein	-
H7786_RS02445 (H7786_02480)	-	467036..467467 (+)	432	WP_082243200.1	histidine kinase	-
H7786_RS02450 (H7786_02485)	stcA	467815..468084 (-)	270	WP_023605037.1	quorum-sensing system protein StcA	-
H7786_RS09140	-	468606..468848 (-)	243	WP_002985713.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80515.39 Da
• Isoelectric Point: 6.8704

>NTDB_id=416532 H7786_RS02420 WP_228646639.1 461788..463941(-) (comA/nlmT) [Streptococcus pyogenes strain TSPY270]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVVYQNKKNYLIIGDPDPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLINFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSQDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIETGSHQELMTKQGFYHHLFSG

Nucleotide

• Length: 2154 bp

>NTDB_id=416532 H7786_RS02420 WP_228646639.1 461788..463941(-) (comA/nlmT) [Streptococcus pyogenes strain TSPY270]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGGTTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCGTCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACCCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAACTTTTTACCTCTT
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCAAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAC
GTCATTTTATCTTACATTCGCCATATTTTTGAATTACCCATGTCTTTTTTTGCAACTCGCAGAACAGGAGAAATCATTTC
ACGGTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCTTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACCAAACTTCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAATTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCGCTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGCA
AAATTATTGAAACAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTGGTTAA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (168-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	73.007	99.721	0.728
comA	Streptococcus mitis NCTC 12261	67.792	99.163	0.672
comA	Streptococcus pneumoniae Rx1	67.37	99.163	0.668
comA	Streptococcus pneumoniae D39	67.37	99.163	0.668
comA	Streptococcus pneumoniae R6	67.37	99.163	0.668
comA	Streptococcus mitis SK321	67.37	99.163	0.668
comA	Streptococcus pneumoniae TIGR4	67.089	99.163	0.665
comA	Streptococcus gordonii str. Challis substr. CH1	66.294	99.721	0.661