Detailed information NTG0414605

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: GU337_RS08295
• Genome accession: NZ_CP047614
• Coordinates: 1628442..1630694 (-)
• Length: 750 a.a.
• NCBI ID: WP_245325866.1
• Uniprot ID: -
• Organism: Lactococcus raffinolactis strain Lr_19_7
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1623442..1635694

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GU337_RS08265 (GU337_08210)	atpA	1623699..1625204 (-)	1506	WP_061773979.1	F0F1 ATP synthase subunit alpha	-
GU337_RS08270 (GU337_08215)	-	1625345..1625872 (-)	528	WP_061773978.1	F0F1 ATP synthase subunit delta	-
GU337_RS08275 (GU337_08220)	atpF	1625875..1626384 (-)	510	WP_061773977.1	F0F1 ATP synthase subunit B	-
GU337_RS08280 (GU337_08225)	atpB	1626397..1627107 (-)	711	WP_096039368.1	F0F1 ATP synthase subunit A	-
GU337_RS08285 (GU337_08230)	-	1627213..1627413 (-)	201	WP_003140734.1	F0F1 ATP synthase subunit C	-
GU337_RS08290 (GU337_08235)	-	1627569..1628363 (-)	795	Protein_1603	alpha/beta hydrolase family protein	-
GU337_RS08295 (GU337_08240)	comEC	1628442..1630694 (-)	2253	WP_245325866.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GU337_RS08300 (GU337_08245)	-	1630660..1631313 (-)	654	WP_244165981.1	helix-hairpin-helix domain-containing protein	-
GU337_RS08305 (GU337_08250)	-	1631371..1632591 (-)	1221	WP_157738471.1	ABC transporter permease	-
GU337_RS08310 (GU337_08255)	-	1632584..1633477 (-)	894	WP_061773972.1	ABC transporter ATP-binding protein	-
GU337_RS08315 (GU337_08260)	-	1633652..1634086 (-)	435	WP_167840164.1	hypothetical protein	-
GU337_RS08320 (GU337_08265)	-	1634142..1634336 (-)	195	WP_061773970.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 750 a.a.
• Molecular weight: 85514.56 Da
• Isoelectric Point: 10.0904

>NTDB_id=414605 GU337_RS08295 WP_245325866.1 1628442..1630694(-) (comEC) [Lactococcus raffinolactis strain Lr_19_7]
MKNLKKALRWINLPSIFIAYFCVLIYYTVFCFSYLLLGYLIISLLILIWQNGIRTCLKLSMILIGFATICLALQDREAKD
FAREMTVTRISPILDTIQVDGDQVSFRGKSGKQTYQVYYRVTTEQEQRYFKQLAQPVVLSISGQLEKASQQRNFNGFDYQ
HHLKTQNIYRVLTIEQVTGVTRKQTLTLALLRQKAILFSEQHFPRPMSAYMTGLLFGHLGKDFEDMSSIYTSLGIMHLFA
LSGMQVSFFIDFLRKGMLRLGFRRDVVDWFQIPFSVFYAGLTGFSISVNRSLVQKILANFGIKALDNFSLTLLLLFITAP
KFLLTTGGTLSLLFAFVISIFGDRFENLPKYRKLLAESLTLSLCVLPLLILYFHTFQPVSIILTFVFSFLFDILFLPGLS
VIFLLAMVTGFTLTQVNLIFQWLEDLIKLTDSWWHYPLVLGKPTALVFLVTLVVTGFLIDHWQNRKVSARLAIILMGLFF
ITKNPPTPSITMVDVGQGDSIFLQDKFNRRSILIDTGGRIELGKKKKWQERKIAAPAEKTLIPYLKSRGVGQIDTLVLTH
THEDHMGDLLAVIDQIKVKNIIVSQGSLNNAQFVKLLKQTRAKVQVAKVGQRLKIFDSYLEVLYPLTPGDGKNNDSIVLY
GKLYGTKFLLTGDLEETGERELLTRYPNLSVDVLKVGHHGSKTSSSESFIEAIRPKVGLISCGLDNRYGHPNMETLTTFQ
KYEVQTFRTDYHGAIKFKKNSKFWHISTVK

Nucleotide

• Length: 2253 bp

>NTDB_id=414605 GU337_RS08295 WP_245325866.1 1628442..1630694(-) (comEC) [Lactococcus raffinolactis strain Lr_19_7]
TTGAAAAACTTAAAGAAAGCATTACGGTGGATTAATCTACCATCGATTTTCATCGCCTATTTTTGTGTGCTGATCTACTA
TACCGTCTTTTGTTTCTCCTATTTACTTTTAGGTTATCTCATCATTTCTTTGCTAATCTTGATCTGGCAAAATGGCATCA
GAACTTGTTTAAAGCTCAGCATGATCTTAATTGGGTTTGCAACCATTTGTCTAGCGCTACAAGATCGTGAAGCTAAAGAT
TTTGCGCGTGAGATGACAGTGACACGGATCAGCCCCATACTGGATACGATTCAGGTGGATGGTGACCAGGTCTCTTTTCG
TGGGAAATCGGGCAAACAAACCTATCAAGTCTATTATAGGGTCACGACGGAACAAGAGCAGCGCTACTTTAAGCAATTAG
CACAACCAGTCGTCCTATCCATTTCAGGTCAACTAGAAAAAGCGAGTCAACAAAGAAATTTCAATGGCTTTGATTATCAA
CACCATCTCAAGACACAAAATATCTATCGAGTTTTGACGATTGAACAGGTGACAGGGGTGACAAGAAAACAAACCTTAAC
CTTAGCGCTCTTACGACAAAAAGCTATTTTGTTTAGTGAGCAACACTTTCCGCGACCTATGTCAGCCTACATGACCGGTT
TACTTTTTGGGCATCTCGGTAAAGATTTTGAAGATATGAGCAGTATCTATACCAGCTTAGGCATCATGCACCTCTTTGCG
CTATCAGGCATGCAAGTGTCATTTTTTATCGACTTTTTAAGAAAGGGTATGCTCAGACTAGGGTTCAGGAGAGATGTTGT
CGATTGGTTTCAAATCCCTTTTTCTGTTTTTTATGCTGGTCTTACAGGATTTTCCATATCTGTCAACAGATCCTTGGTCC
AGAAAATCCTAGCTAATTTTGGAATTAAGGCGCTTGACAATTTCAGTCTCACGTTGTTGCTTCTATTTATCACGGCGCCA
AAATTCCTTTTAACCACAGGCGGCACCTTGTCTTTACTTTTTGCCTTCGTCATTTCAATCTTTGGCGATCGCTTTGAGAA
CCTCCCAAAATATCGTAAACTACTAGCAGAAAGTTTAACCCTTTCTCTATGCGTTTTACCGCTCCTCATCCTTTATTTTC
ACACCTTCCAACCAGTGTCGATCATCTTGACCTTTGTCTTCAGCTTTCTTTTTGATATTCTCTTCCTACCAGGTCTATCC
GTCATTTTCTTGCTAGCAATGGTAACAGGCTTCACGCTAACACAAGTCAATCTCATTTTTCAGTGGCTTGAAGACCTTAT
CAAATTGACAGATAGCTGGTGGCATTATCCGTTAGTACTTGGTAAACCAACAGCCTTGGTCTTTCTGGTGACGCTAGTTG
TGACAGGTTTTTTAATTGACCACTGGCAAAATCGAAAAGTTAGTGCTAGGCTGGCAATCATCTTGATGGGCTTATTCTTC
ATAACTAAAAATCCACCGACTCCTTCGATAACCATGGTGGATGTTGGCCAGGGGGATAGTATTTTCTTACAAGATAAGTT
TAATCGACGCAGTATTTTAATCGATACAGGTGGCAGGATTGAACTAGGTAAGAAGAAAAAGTGGCAGGAGCGTAAAATTG
CAGCACCAGCTGAAAAGACTTTAATTCCTTATTTGAAAAGTCGGGGTGTGGGTCAGATTGATACTTTGGTTCTAACCCAT
ACTCACGAGGACCATATGGGTGACCTACTCGCTGTCATCGACCAAATTAAGGTCAAAAATATCATCGTGAGTCAAGGCAG
TCTCAATAATGCCCAATTTGTCAAACTCTTAAAGCAAACCCGAGCTAAGGTTCAAGTGGCCAAGGTCGGTCAACGACTAA
AGATTTTTGACAGCTATTTGGAAGTTCTGTATCCATTGACCCCAGGAGATGGTAAAAATAATGACTCGATCGTCTTGTAT
GGTAAGCTCTATGGTACAAAATTTTTGTTAACAGGTGATTTGGAGGAGACAGGCGAGCGAGAGTTGTTGACACGTTATCC
CAATCTCTCAGTTGATGTTTTAAAAGTAGGGCATCATGGCTCAAAAACGTCATCTTCTGAGTCTTTTATTGAAGCGATTC
GACCAAAAGTCGGATTGATTTCTTGTGGTTTGGATAATCGGTACGGTCATCCAAATATGGAAACTCTCACAACCTTCCAG
AAATATGAGGTTCAAACTTTTCGAACAGATTATCATGGTGCTATAAAATTTAAGAAAAACAGTAAATTTTGGCACATCTC
GACAGTAAAGTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (214-463)

• Domain of unknown function (DUF4131) (DUF4131) (34-178)

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-703)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	51.687	98.8	0.511
comEC/celB	Streptococcus mitis NCTC 12261	46.817	100	0.471
comEC/celB	Streptococcus mitis SK321	46.235	100	0.467
comEC/celB	Streptococcus pneumoniae TIGR4	45.358	100	0.456
comEC/celB	Streptococcus pneumoniae Rx1	43.857	100	0.443
comEC/celB	Streptococcus pneumoniae D39	43.857	100	0.443
comEC/celB	Streptococcus pneumoniae R6	43.857	100	0.443