Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   HMPREF0833_RS10110 Genome accession   NC_015678
Coordinates   2145034..2146902 (+) Length   622 a.a.
NCBI ID   WP_013904762.1    Uniprot ID   -
Organism   Streptococcus parasanguinis ATCC 15912     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2140034..2151902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0833_RS10095 (HMPREF0833_12013) fmt 2142037..2142972 (+) 936 WP_003018099.1 methionyl-tRNA formyltransferase -
  HMPREF0833_RS10100 (HMPREF0833_12014) rsmB 2142962..2144275 (+) 1314 WP_003018094.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  HMPREF0833_RS10105 (HMPREF0833_12015) - 2144297..2145037 (+) 741 WP_003018086.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  HMPREF0833_RS10110 (HMPREF0833_12016) stkP 2145034..2146902 (+) 1869 WP_013904762.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  HMPREF0833_RS10115 (HMPREF0833_12017) - 2147505..2149295 (+) 1791 WP_041818462.1 CAP domain-containing protein -
  HMPREF0833_RS10120 (HMPREF0833_12018) liaF 2149470..2150165 (+) 696 WP_013904764.1 cell wall-active antibiotics response protein LiaF -
  HMPREF0833_RS10125 (HMPREF0833_12019) - 2150162..2151178 (+) 1017 WP_013904765.1 sensor histidine kinase -
  HMPREF0833_RS10130 (HMPREF0833_12020) - 2151175..2151807 (+) 633 WP_013904766.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 622 a.a.        Molecular weight: 68728.89 Da        Isoelectric Point: 5.8369

>NTDB_id=41418 HMPREF0833_RS10110 WP_013904762.1 2145034..2146902(+) (stkP) [Streptococcus parasanguinis ATCC 15912]
MIQIGKIFAGRYKIIQQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMAELDHPNIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKENAPLSNEEAVRLMGQILLAMRLAHTRGIIHRDLKPQNVLLTPDGTAKVSDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIREENKNVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSCLSYERRNEKKLVFEDQTKADTKTLPKVSPTPKTAPVPISEVRSEISSV
DPKRPLSNQQVVAPNKKPRRRLRARYKVLFVAIALVLAAFTFLLYMSPANKTVPDVSGKTIAEARAIIEGQDLQVGEEKE
EYSDTVAEGYVIRTNPNAGAQKREQSRIDLIVSKGPNSFEMPNYVGETRAKAEDDLKNTYKVSSKMISIEEVETFDYDPG
TVIEQTPAAGEQYSLNSKTKIVLKVAKETTSIEMPNYIGSTYDFARSNLIEIYDIKEANIELRKTDHLPDGVVVSAGQIV
SQTPEASNTVDINRTRIILTVYEPKVTSSSSTKASSSSETSSSSSSDRKDTDSSSSSAADDD

Nucleotide


Download         Length: 1869 bp        

>NTDB_id=41418 HMPREF0833_RS10110 WP_013904762.1 2145034..2146902(+) (stkP) [Streptococcus parasanguinis ATCC 15912]
ATGATTCAAATCGGCAAAATTTTTGCCGGGCGATATAAAATCATCCAACAAATTGGGCGCGGCGGGATGGCAGATGTTTA
TCTTGCGCGTGATTTGATTTTAGATGGTGAAGAAGTTGCAGTCAAGGTACTGCGTACGAATTATCAGACGGATCCCATTG
CAGTTGCTCGTTTTCAGCGGGAAGCAAAAGCGATGGCGGAACTGGACCATCCAAATATCGTTCGGATTACAGACATTGGC
GAAGAAGAAGGGCAACAATACCTTGCAATGGAATATGTTGCAGGTTTAGACTTGAAACGCTATATCAAAGAAAATGCACC
TTTATCAAATGAAGAAGCGGTTCGTTTGATGGGACAGATTCTCCTTGCTATGCGTCTAGCCCATACGCGTGGCATTATCC
ATAGAGATTTAAAACCACAGAATGTCCTCTTGACTCCGGATGGGACTGCAAAAGTTTCAGACTTTGGGATTGCAGTGGCC
TTTGCAGAGACAAGCTTGACCCAGACCAACTCTATGTTAGGATCAGTCCATTATTTGTCACCTGAGCAGGCACGGGGATC
GAAAGCTACGGTTCAAAGTGACATTTACGCTATGGGAATTATTTTCTATGAGATGTTGACTGGACACATTCCTTATGATG
GGGATAGTGCGGTTACGATTGCACTGCAACATTTCCAAAAACCTCTTCCCTCTATTCGTGAAGAAAATAAGAATGTTCCG
CAAGCTTTAGAAAATGTTGTGATCAAAGCGACGGCTAAGAAGCTGACGGACCGTTATAAGTCAGTAGCAGAGATGTATGT
AGATCTTTCAAGCTGCCTGTCTTATGAGAGGAGAAATGAGAAAAAGCTGGTTTTTGAAGATCAAACAAAGGCTGATACAA
AAACTCTTCCGAAAGTGAGTCCGACTCCAAAGACCGCTCCAGTTCCAATCTCTGAGGTGCGCAGTGAAATCAGTTCGGTG
GATCCAAAACGGCCATTATCCAACCAGCAGGTCGTGGCACCAAATAAAAAGCCAAGAAGACGCTTACGTGCACGTTATAA
AGTATTGTTTGTTGCAATCGCGCTAGTTCTTGCTGCCTTTACCTTCTTGTTGTATATGAGTCCAGCCAATAAAACAGTTC
CGGATGTTTCTGGTAAGACTATTGCTGAGGCCAGAGCGATTATCGAAGGTCAAGATCTTCAAGTTGGTGAAGAAAAGGAA
GAATATAGTGATACTGTTGCGGAAGGCTATGTCATTCGAACTAATCCAAATGCGGGAGCTCAAAAGAGGGAACAAAGTCG
AATTGATTTGATTGTTTCAAAGGGACCAAATAGCTTTGAAATGCCAAATTATGTAGGAGAAACGAGGGCAAAAGCAGAGG
ATGATCTGAAAAATACTTATAAAGTGTCAAGTAAGATGATCAGTATAGAGGAAGTTGAAACTTTTGACTATGATCCTGGG
ACGGTTATTGAGCAAACACCGGCAGCAGGTGAGCAATATTCTTTGAATTCAAAAACTAAGATTGTATTAAAAGTAGCAAA
AGAAACAACTTCAATTGAAATGCCAAACTATATTGGATCAACCTATGATTTCGCACGTAGCAATTTGATTGAAATATATG
ACATCAAGGAAGCCAATATTGAATTAAGAAAAACGGACCATCTTCCTGATGGGGTTGTTGTTTCTGCAGGGCAAATTGTG
AGTCAAACTCCTGAGGCATCTAATACAGTGGATATTAATCGGACCAGAATTATATTGACAGTGTATGAGCCTAAAGTGAC
TTCTTCTTCAAGTACGAAAGCTTCTTCAAGTTCAGAAACGTCTAGTTCGTCTTCATCAGATCGAAAGGATACCGATAGTT
CAAGTAGTAGTGCAGCAGATGATGATTAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-245)

PASTA domain (PASTA)

(440-507)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(512-582)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

61.706

96.141

0.593
  stkP Streptococcus pneumoniae D39

61.538

96.141

0.592
  stkP Streptococcus pneumoniae R6

61.538

96.141

0.592
  stkP Streptococcus pneumoniae Rx1

61.371

96.141

0.59
  pknB Streptococcus mutans UA159

60.264

85.37

0.514
  stkP/pknB Streptococcus salivarius strain HSISS4

53.833

94.373

0.508

Multiple sequence alignment