Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HMPREF0833_RS09640 Genome accession   NC_015678
Coordinates   2045182..2045919 (+) Length   245 a.a.
NCBI ID   WP_013904700.1    Uniprot ID   A0AAW7P481
Organism   Streptococcus parasanguinis ATCC 15912     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 2040182..2050919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0833_RS09625 (HMPREF0833_11923) - 2040515..2042077 (-) 1563 WP_013904697.1 ABC transporter substrate-binding protein/permease -
  HMPREF0833_RS09630 (HMPREF0833_11924) - 2042195..2044102 (+) 1908 WP_041818452.1 DUF2207 domain-containing protein -
  HMPREF0833_RS09635 (HMPREF0833_11925) - 2044211..2045047 (+) 837 WP_013904699.1 undecaprenyl-diphosphate phosphatase -
  HMPREF0833_RS09640 (HMPREF0833_11926) mecA 2045182..2045919 (+) 738 WP_013904700.1 adaptor protein MecA Regulator
  HMPREF0833_RS09645 (HMPREF0833_11927) - 2045916..2047073 (+) 1158 WP_013904701.1 glycosyltransferase family 4 protein -
  HMPREF0833_RS09650 (HMPREF0833_11928) sufC 2047208..2047978 (+) 771 WP_003004238.1 Fe-S cluster assembly ATPase SufC -
  HMPREF0833_RS09655 (HMPREF0833_11929) sufD 2048045..2049307 (+) 1263 WP_013904702.1 Fe-S cluster assembly protein SufD -
  HMPREF0833_RS09660 (HMPREF0833_11930) - 2049317..2050543 (+) 1227 WP_013904703.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28335.01 Da        Isoelectric Point: 4.0769

>NTDB_id=41410 HMPREF0833_RS09640 WP_013904700.1 2045182..2045919(+) (mecA) [Streptococcus parasanguinis ATCC 15912]
MKMKQISDSTIKITIQLEDLEERGMEIADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQQLDFEDLSDLPDMEELSRMTPDEFIKTLEKTISDKTKGDAEAIHHLEQEELRDNQEQDPTPESPVTQYIYYILRFSNI
QQAVAFSKTVTYPVDTSELYKMGSEYYLTVLIDTENQPIQYPTWLLATIREYADDSEVTRAVLQEHGYLLMVSGAIENLK
KVASL

Nucleotide


Download         Length: 738 bp        

>NTDB_id=41410 HMPREF0833_RS09640 WP_013904700.1 2045182..2045919(+) (mecA) [Streptococcus parasanguinis ATCC 15912]
ATGAAGATGAAGCAAATTAGTGATTCAACAATTAAGATCACGATCCAACTAGAAGACTTAGAAGAACGTGGGATGGAAAT
TGCTGATTTTCTTGTCCCACAAGAAAAAACAGAAGAATTTTTCTACGCCATTTTGGATGAACTCGAAATGCCAGAAAGCT
TCCTGGATAGCGGGATGCTGAGTTTTCGTGTGACGCCAAAACCAGATAAATTGGATGTTTTTGTTACCAAATCAAAAATT
GACCAACAATTGGATTTTGAGGATTTGTCAGATCTTCCTGATATGGAAGAGTTGTCGCGCATGACGCCAGATGAATTTAT
CAAAACCTTGGAAAAAACAATCTCTGATAAGACAAAAGGGGATGCAGAAGCCATTCACCATTTGGAACAAGAAGAGTTAC
GTGATAATCAAGAACAAGATCCGACACCTGAATCCCCAGTGACTCAGTATATTTATTACATTTTGCGTTTTTCGAATATC
CAGCAAGCAGTTGCCTTTTCCAAAACGGTGACTTACCCAGTAGATACCTCTGAATTGTACAAGATGGGGTCGGAATATTA
TTTGACAGTGCTAATTGATACAGAGAATCAGCCTATCCAATATCCTACTTGGTTACTCGCAACTATTCGAGAGTATGCGG
ATGATTCAGAAGTGACACGGGCAGTTTTACAGGAGCATGGGTATTTATTGATGGTATCAGGTGCGATAGAGAATTTAAAG
AAAGTTGCTAGTTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

67.755

100

0.678
  mecA Streptococcus pneumoniae D39

67.755

100

0.678
  mecA Streptococcus pneumoniae R6

67.755

100

0.678
  mecA Streptococcus pneumoniae TIGR4

67.755

100

0.678
  mecA Streptococcus mutans UA159

49.798

100

0.502
  mecA Streptococcus thermophilus LMD-9

47.347

100

0.473
  mecA Streptococcus thermophilus LMG 18311

46.939

100

0.469

Multiple sequence alignment