Detailed information NTG0413692

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: I5102_RS12400
• Genome accession: NZ_CP060240
• Coordinates: 2623504..2624175 (+)
• Length: 223 a.a.
• NCBI ID: WP_003090494.1
• Uniprot ID: A0A0H2ZC88
• Organism: Pseudomonas aeruginosa strain G-I-1
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2618504..2629175

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I5102_RS12365 (I5102_002537)	ppyR	2618977..2619234 (+)	258	WP_003090502.1	psl/pyoverdine operon transcriptional regulator PpyR	-
I5102_RS12370 (I5102_002538)	-	2619221..2620414 (+)	1194	WP_023109946.1	NnrS family protein	-
I5102_RS12375 (I5102_002539)	-	2620415..2620681 (-)	267	WP_003090500.1	DUF5329 domain-containing protein	-
I5102_RS12380 (I5102_002540)	-	2620665..2621558 (-)	894	WP_134287880.1	hypothetical protein	-
I5102_RS12385 (I5102_002541)	-	2621585..2622667 (-)	1083	WP_196331937.1	patatin-like phospholipase family protein	-
I5102_RS12390 (I5102_002542)	-	2622882..2623190 (+)	309	WP_003090497.1	PepSY domain-containing protein	-
I5102_RS12395 (I5102_002543)	-	2623190..2623504 (+)	315	WP_003097704.1	PepSY domain-containing protein	-
I5102_RS12400 (I5102_002544)	ciaR	2623504..2624175 (+)	672	WP_003090494.1	two-component system response regulator CarR	Regulator
I5102_RS12405 (I5102_002545)	carS	2624172..2625509 (+)	1338	WP_003090493.1	two-component system sensor histidine kinase CarS	-
I5102_RS12410 (I5102_002546)	-	2625600..2625908 (+)	309	WP_003097699.1	hypothetical protein	-
I5102_RS30525	-	2625913..2626449 (-)	537	Protein_2460	methyl-accepting chemotaxis protein	-
I5102_RS30530	-	2626819..2628057 (-)	1239	Protein_2461	chemotaxis protein	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 24729.20 Da
• Isoelectric Point: 5.8445

>NTDB_id=413692 I5102_RS12400 WP_003090494.1 2623504..2624175(+) (ciaR) [Pseudomonas aeruginosa strain G-I-1]
MRLLLVEDHVPLADELMASLTRQGYAVDWLADGRDAAVQGASEPYDLIILDLGLPGRPGLEILQEWRGLGLATPVLILTA
RGSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRRAHGLANQSQLEAAGLRLDEQRQCVCLNGADVDLTAAEFRLLR
YFMLHPGQVLSKGHLAEHLYDGETERDSNVIEVHVNHLRRKLGREVIETRRGQGYRYAGVAAG

Nucleotide

• Length: 672 bp

>NTDB_id=413692 I5102_RS12400 WP_003090494.1 2623504..2624175(+) (ciaR) [Pseudomonas aeruginosa strain G-I-1]
ATGCGGTTGCTGCTGGTTGAGGATCACGTTCCCCTGGCCGACGAACTGATGGCCAGCCTGACCCGCCAGGGCTACGCGGT
GGACTGGCTGGCCGACGGCCGCGACGCGGCGGTGCAGGGCGCCAGCGAACCCTACGACCTGATCATCCTCGACCTCGGCC
TGCCCGGGCGTCCCGGCCTGGAGATACTCCAGGAGTGGCGTGGGCTGGGACTCGCGACTCCGGTGCTGATCCTCACCGCG
CGCGGTTCCTGGGCCGAACGCATCGATGGGCTCAAGGCCGGTGCCGACGACTACCTGACCAAGCCGTTCCATCCGGAAGA
GCTGGCCTTGCGCATCCAGGCCCTGTTGCGCCGCGCCCATGGGCTGGCCAACCAGAGCCAGCTGGAGGCCGCCGGGCTGC
GCCTGGACGAGCAGCGCCAGTGCGTGTGCCTGAACGGCGCCGACGTCGACCTGACCGCCGCCGAATTCCGCCTGCTGCGC
TATTTCATGCTGCACCCCGGCCAGGTCCTGTCCAAGGGGCACCTGGCCGAGCATCTGTACGACGGCGAGACCGAACGCGA
TTCCAACGTCATCGAGGTCCACGTCAACCACCTGCGGCGCAAGCTCGGCCGCGAGGTGATCGAGACCCGCCGTGGCCAGG
GCTACCGCTACGCCGGGGTGGCCGCCGGATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-216)

3D structure

• AlphaFold DB: A0A0H2ZC88

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	37.727	98.655	0.372
ciaR	Streptococcus pneumoniae Rx1	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae D39	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae R6	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae TIGR4	37.273	98.655	0.368
micA	Streptococcus pneumoniae Cp1015	35.683	100	0.363
vicR	Streptococcus mutans UA159	35.526	100	0.363