Detailed information NTG0413332

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: GTO82_RS03000
• Genome accession: NZ_CP047409
• Coordinates: 635131..637290 (+)
• Length: 719 a.a.
• NCBI ID: WP_180873680.1
• Uniprot ID: A0A9X7U0F5
• Organism: Lactobacillus johnsonii strain 3DG
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 630131..642290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GTO82_RS02970 (GTO82_02975)	-	630140..630367 (+)	228	WP_004896914.1	hypothetical protein	-
GTO82_RS02975 (GTO82_02980)	udk	630394..631029 (-)	636	WP_004895448.1	uridine kinase	-
GTO82_RS02980 (GTO82_02985)	-	631358..631513 (+)	156	WP_127835551.1	lactacin F inducer peptide precursor	-
GTO82_RS02985 (GTO82_02990)	-	631614..632822 (+)	1209	WP_260983179.1	GHKL domain-containing protein	-
GTO82_RS02990 (GTO82_02995)	-	632966..634123 (+)	1158	WP_127835553.1	RNA-guided endonuclease TnpB family protein	-
GTO82_RS02995 (GTO82_03000)	-	634321..635118 (+)	798	WP_180873679.1	LytTR family DNA-binding domain-containing protein	-
GTO82_RS03000 (GTO82_03005)	comA	635131..637290 (+)	2160	WP_180873680.1	peptide cleavage/export ABC transporter	Regulator
GTO82_RS03005 (GTO82_03010)	-	637301..637894 (+)	594	WP_180873681.1	hypothetical protein	-
GTO82_RS03010 (GTO82_03015)	-	637939..638223 (+)	285	WP_127835555.1	bacteriocin immunity protein	-
GTO82_RS03015 (GTO82_03020)	-	638353..638586 (+)	234	WP_127835556.1	hypothetical protein	-
GTO82_RS03020 (GTO82_03025)	-	638630..638905 (+)	276	WP_127835557.1	hypothetical protein	-
GTO82_RS03025 (GTO82_03030)	-	639110..639340 (+)	231	WP_094497872.1	hypothetical protein	-
GTO82_RS03030 (GTO82_03035)	-	639464..639778 (+)	315	WP_004896933.1	bacteriocin immunity protein	-
GTO82_RS03035 (GTO82_03040)	-	639781..640065 (+)	285	WP_004896934.1	hypothetical protein	-

Sequence

Protein

• Length: 719 a.a.
• Molecular weight: 81089.35 Da
• Isoelectric Point: 7.0538

>NTDB_id=413332 GTO82_RS03000 WP_180873680.1 635131..637290(+) (comA) [Lactobacillus johnsonii strain 3DG]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYQSRVSLAHLRHEARTNLEGTTTLGLVKTAQKFNFKTEAVKADMSLFNEDT
IQYPFIVHVLKQGELLHYYVVLKNTKNYLVIADPDPSVGIIKMPKDKFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYIFNSIFSYGQNFLLNVLGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLAIVIVMGLVLAAQNMTLFGITLLALPVYA
VVILGFTKKFEKLNDEQMESNAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVNYLKKSFKYSKAESLQTALKTFIQ
LSLNVIILWVGARVVMQGQMSIGQLMTFNALLSYFIDPLQNIINLQPRLQSASVAQNRLNEVYQVQSEFNADTSIQNSAA
LEGMIEYKHVDYRYGYGTDVLKNINLKIKPDEKLAIVGMSGSGKSTMVKLLVDFFSPSKGEVTLNGHATSEVNKHTLRSY
VNYVPQTPYIFSGTVKKNLLLGCRPDISEEDVIKACQIAGIDQEIASLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVVDNLMKLKDKTIIFIAHRLAIAERADKVVVIDQGQIVEEGSHEELMEQHGFYYDLVKG

Nucleotide

• Length: 2160 bp

>NTDB_id=413332 GTO82_RS03000 WP_180873680.1 635131..637290(+) (comA) [Lactobacillus johnsonii strain 3DG]
ATGTTATTCAAATATAAATCTGTTTATGTACCTCAAGTAGATGAGATGGATTGCGGAGTTGCTTGTCTAGCAATGATCTT
AAAGCAGTATCAATCTCGTGTGTCTTTAGCACATTTGCGTCACGAAGCTCGCACAAATCTTGAAGGCACAACTACGCTGG
GACTAGTTAAAACAGCACAGAAATTTAATTTTAAAACTGAAGCCGTAAAAGCTGATATGTCTCTTTTTAATGAGGATACT
ATTCAATACCCTTTTATCGTGCATGTTCTTAAGCAAGGAGAATTACTTCATTATTACGTAGTTCTTAAAAATACTAAGAA
TTACTTAGTAATTGCCGATCCTGATCCATCAGTTGGCATAATAAAGATGCCTAAAGATAAATTTGCTCAAGAATGGACTG
GTATTGCGCTTTTTATGGTTCCGAATGAAGATTTTGAACCAATTAAAGAAAAGAAAAATAACCTATGGTCTCTCTTTCCA
TATATGTTTAAGCAAAAGCGGCTGATGATTAATATCATTTTAGCCGCTTTATTAATGACAATAATTAGTATTTGTAGTTC
ATACTTTGTGCAAGGAATAATCGATACTTATATTCCCGATGGAACTTATCAGACTCTTTCAATTTTAGCTGTTGGACTAT
TAATTGCTTATATTTTTAATTCAATCTTTTCTTATGGACAGAATTTTTTATTAAATGTTCTAGGTCAAAGATTAAGTATT
GATTTAAACCTCCAATATATAAGGCATATTTTTGAATTGCCAATGGAATTCTTTGTGACTAGAAGAACTGGTGAAATAAC
CTCACGTTTCTCTGATGCAAGTAGAATTATTGATGCTCTAGCAAGTACTGTTATTTCACTTTTCTTAGACTTAGCGATTG
TAATTGTAATGGGACTAGTGTTAGCTGCTCAAAATATGACCTTATTTGGAATCACATTATTAGCTTTACCAGTATATGCT
GTAGTAATTCTGGGATTTACTAAGAAATTTGAAAAGTTAAATGATGAACAAATGGAGAGCAATGCAGTACTAAGTTCTTC
AGTCATCGAAGATATTCAAGGTATTGAAACTATCAAAGCTCTCAATAGTGAAGATACAAGATATCGTAGAATCGATAGCC
AATTTGTAAATTATTTAAAGAAGTCATTTAAATATAGTAAGGCTGAGAGTTTGCAGACGGCGTTAAAGACATTTATTCAA
CTATCTCTTAATGTAATTATTTTATGGGTTGGCGCACGAGTAGTGATGCAAGGACAGATGAGTATCGGTCAATTAATGAC
TTTTAATGCGTTACTATCTTATTTCATTGACCCACTTCAAAATATTATTAACTTACAACCTCGTCTTCAATCAGCTAGTG
TTGCACAAAATAGATTGAACGAGGTTTATCAGGTGCAAAGTGAATTTAATGCAGATACTTCTATCCAGAACTCAGCTGCT
TTAGAAGGAATGATTGAATACAAGCATGTTGATTATCGATATGGTTATGGGACGGATGTTTTAAAAAACATTAATCTAAA
AATTAAGCCAGATGAAAAATTAGCAATTGTTGGCATGAGTGGATCAGGAAAATCGACAATGGTTAAGTTACTCGTTGATT
TCTTTTCACCAAGTAAGGGAGAAGTAACTTTAAATGGTCATGCAACTAGTGAAGTTAATAAACATACCTTACGCTCATAT
GTTAACTATGTTCCTCAAACGCCATATATCTTTTCTGGAACAGTTAAGAAGAATTTATTACTCGGCTGCAGACCGGATAT
TAGCGAAGAAGATGTAATTAAAGCCTGTCAGATTGCTGGAATTGATCAGGAGATAGCTAGTTTGCCACTACAATTCGAGA
CAAAGTTAGATGAGAATGCCAAGATTTTATCCGGTGGACAAAAGCAGAGATTAACTATTGCTAGAGCATTACTCTCGCCA
GCAAAAGTTTTTATCTTTGATGAAGTAACAAGTGGTTTAGATACAATTACAGAAAAAAGAGTAGTTGACAATCTTATGAA
ACTAAAAGACAAGACAATCATTTTTATTGCACACCGTCTAGCCATTGCAGAACGTGCAGATAAGGTGGTTGTAATTGACC
AGGGGCAGATTGTTGAAGAAGGAAGTCATGAAGAGCTTATGGAGCAACATGGTTTTTATTATGACTTAGTAAAGGGATAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (501-651)

• Peptidase C39 family (Peptidase_C39) (7-143)

• ABC transporter transmembrane region (ABC_membrane) (169-439)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	56.742	99.026	0.562
comA	Streptococcus mitis SK321	56.32	99.026	0.558
comA	Streptococcus pneumoniae Rx1	56.18	99.026	0.556
comA	Streptococcus pneumoniae D39	56.18	99.026	0.556
comA	Streptococcus pneumoniae R6	56.18	99.026	0.556
comA	Streptococcus pneumoniae TIGR4	56.039	99.026	0.555
comA	Streptococcus gordonii str. Challis substr. CH1	54.916	99.026	0.544
comA/nlmT	Streptococcus mutans UA159	53.182	98.331	0.523