Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   H5J27_RS12960 Genome accession   NZ_CP059995
Coordinates   2739334..2740005 (+) Length   223 a.a.
NCBI ID   WP_033968082.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain NY3045     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2734334..2745005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H5J27_RS12925 (H5J27_12925) ppyR 2734807..2735064 (+) 258 WP_003090502.1 psl/pyoverdine operon transcriptional regulator PpyR -
  H5J27_RS12930 (H5J27_12930) - 2735051..2736244 (+) 1194 WP_033968078.1 NnrS family protein -
  H5J27_RS12935 (H5J27_12935) - 2736245..2736511 (-) 267 WP_033968079.1 DUF5329 domain-containing protein -
  H5J27_RS12940 (H5J27_12940) - 2736495..2737388 (-) 894 WP_042163452.1 hypothetical protein -
  H5J27_RS12945 (H5J27_12945) - 2737415..2738497 (-) 1083 WP_003113385.1 hypothetical protein -
  H5J27_RS12950 (H5J27_12950) - 2738712..2739020 (+) 309 WP_003090497.1 PepSY domain-containing protein -
  H5J27_RS12955 (H5J27_12955) - 2739020..2739334 (+) 315 WP_003097704.1 PepSY domain-containing protein -
  H5J27_RS12960 (H5J27_12960) ciaR 2739334..2740005 (+) 672 WP_033968082.1 two-component system response regulator CarR Regulator
  H5J27_RS12965 (H5J27_12965) carS 2740002..2741339 (+) 1338 WP_033968084.1 two-component system sensor histidine kinase CarS -
  H5J27_RS12970 (H5J27_12970) - 2741430..2741738 (+) 309 WP_003097699.1 hypothetical protein -
  H5J27_RS12975 (H5J27_12975) - 2741743..2743887 (-) 2145 WP_042163457.1 methyl-accepting chemotaxis protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24743.22 Da        Isoelectric Point: 5.8445

>NTDB_id=412196 H5J27_RS12960 WP_033968082.1 2739334..2740005(+) (ciaR) [Pseudomonas aeruginosa strain NY3045]
MRLLLVEDHVPLADELMASLTRQGYAVDWLADGRDAALQGASEPYDLIILDLGLPGRPGLEILQEWRGLGLATPVLILTA
RGSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRRAHGLANQSQLEAAGLRLDEQRQCVCLNGADVDLTAAEFRLLR
YFMLHPGQVLSKGHLAEHLYDGETERDSNVIEVHVNHLRRKLGREVIETRRGQGYRYAGVAAG

Nucleotide


Download         Length: 672 bp        

>NTDB_id=412196 H5J27_RS12960 WP_033968082.1 2739334..2740005(+) (ciaR) [Pseudomonas aeruginosa strain NY3045]
ATGCGGTTGCTGCTGGTTGAGGATCACGTTCCCCTGGCCGACGAACTGATGGCCAGCCTGACCCGCCAGGGCTACGCGGT
GGACTGGCTGGCCGACGGCCGCGACGCGGCGCTGCAGGGCGCCAGCGAACCCTACGACCTGATCATCCTCGACCTCGGCC
TGCCCGGGCGTCCCGGCCTGGAGATACTCCAGGAGTGGCGTGGCCTGGGCCTCGCGACTCCGGTGCTGATCCTCACCGCG
CGCGGTTCCTGGGCCGAGCGCATCGATGGGCTCAAGGCCGGCGCCGACGACTACCTGACCAAACCGTTCCATCCGGAAGA
GCTGGCCTTGCGCATCCAGGCCCTGTTGCGCCGCGCCCATGGGCTGGCCAACCAGAGCCAGCTGGAGGCCGCCGGGCTGC
GCCTGGACGAGCAGCGCCAGTGCGTGTGCCTGAACGGCGCCGACGTCGACCTGACCGCCGCCGAATTCCGCCTGCTGCGC
TATTTCATGCTGCACCCCGGCCAGGTCCTGTCCAAGGGGCACCTGGCCGAGCATCTGTACGACGGCGAGACCGAACGCGA
TTCCAACGTCATCGAGGTCCACGTCAACCACCTGCGGCGCAAGCTCGGTCGCGAGGTGATCGAGACCCGCCGCGGCCAGG
GCTACCGCTACGCCGGGGTGGCCGCCGGATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-216)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

37.727

98.655

0.372
  ciaR Streptococcus pneumoniae Rx1

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae D39

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae R6

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae TIGR4

37.273

98.655

0.368
  micA Streptococcus pneumoniae Cp1015

35.683

100

0.363
  vicR Streptococcus mutans UA159

35.526

100

0.363