Detailed information NTG0411394

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: GQY29_RS04930
• Genome accession: NZ_CP047191
• Coordinates: 915836..917989 (+)
• Length: 717 a.a.
• NCBI ID: WP_041827378.1
• Uniprot ID: A0A811IIL9
• Organism: Streptococcus thermophilus strain EU01
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 910836..922989

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GQY29_RS10710 (GQY29_04915)	-	910933..911139 (+)	207	WP_011681579.1	hypothetical protein	-
GQY29_RS04920 (GQY29_04920)	-	911327..913084 (+)	1758	WP_023909920.1	ABC transporter transmembrane domain-containing protein	-
GQY29_RS04925 (GQY29_04925)	-	913077..914822 (+)	1746	WP_023909918.1	ABC transporter ATP-binding protein	-
GQY29_RS04930 (GQY29_04930)	comA/nlmT	915836..917989 (+)	2154	WP_041827378.1	peptide cleavage/export ABC transporter	Regulator
GQY29_RS04935 (GQY29_04935)	-	918005..919372 (+)	1368	WP_011681574.1	bacteriocin secretion accessory protein	-
GQY29_RS04940 (GQY29_04940)	-	919387..919548 (+)	162	WP_011681573.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
GQY29_RS10715	-	919566..920369 (-)	804	WP_223899638.1	ATP-binding protein	-
GQY29_RS04950 (GQY29_04950)	-	920900..921637 (-)	738	WP_011681571.1	response regulator transcription factor	-
GQY29_RS04955 (GQY29_04955)	-	921887..922063 (+)	177	WP_011681570.1	Blp family class II bacteriocin	-
GQY29_RS04960 (GQY29_04960)	-	922082..922282 (+)	201	WP_011681569.1	hypothetical protein	-
GQY29_RS04965 (GQY29_04965)	-	922639..922869 (+)	231	WP_014608662.1	bacteriocin class II family protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80644.44 Da
• Isoelectric Point: 6.8843

>NTDB_id=411394 GQY29_RS04930 WP_041827378.1 915836..917989(+) (comA/nlmT) [Streptococcus thermophilus strain EU01]
MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDV
PYPFIAHVNKDGKLQHYYVIYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRFTID
VILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTL
IVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide

• Length: 2154 bp

>NTDB_id=411394 GQY29_RS04930 WP_041827378.1 915836..917989(+) (comA/nlmT) [Streptococcus thermophilus strain EU01]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGGATTGTGGAGTTGCTGCCTTGGCATCAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCACATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTTGAAACGAGAGCTATAAAGGCTGAAATGTCGCTCTTTGAGATGGAAGATGTT
CCTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAGCACCAAGGATTA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTG
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTAATATTGTCTTTGCCAGTCTCTTGGTTACTTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTAGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATGACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCAGCGATTTACCATTGAC
GTTATCTTGTCCTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTATCTC
ACGTTTTAGTGATGCTAACTCTATTATCGATGCTCTGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTCTTATTGATACAAAATAGCAATCTCTTCAAGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTCTTTGCCTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAATTCAGCCAT
CATTGAGGACATTAATGGGATTGAAACCATAAAGTCACTAACCAGCGAAGAAGTATGCTATCAAAAGATTGATGGTGAGT
TTATTGACTATCTAGACAATTCTTTTCGCCTTTCTAAGTTATCTATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGTTGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCTTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTAAGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGATATCACTGTTACGGATTTATCTTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTTTGACGAT
TAGACAAGGAGAAAAAATCAGTTTTGTTGGTGTCAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTGGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCTGATATTTTGAAAGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGCGCGTGCACTACTAACGAAATCTCCT
GTACTAATCTTAGATGAAGCAACTAGCGGATTGGATGTTTTGACAGAAAAGCAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACGATCATCTTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTGATCACGGAC
GCGTAGTGGAGACAGGTTCTCATCAAGACCTAATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

3D structure

• AlphaFold DB: A0A811IIL9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	67.787	99.582	0.675
comA	Streptococcus mitis NCTC 12261	66.104	99.163	0.656
comA	Streptococcus pneumoniae Rx1	65.682	99.163	0.651
comA	Streptococcus pneumoniae D39	65.682	99.163	0.651
comA	Streptococcus pneumoniae R6	65.682	99.163	0.651
comA	Streptococcus mitis SK321	65.401	99.163	0.649
comA	Streptococcus pneumoniae TIGR4	65.26	99.163	0.647
comA	Streptococcus gordonii str. Challis substr. CH1	64.006	99.582	0.637