Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GQY29_RS01960 Genome accession   NZ_CP047191
Coordinates   378004..378753 (-) Length   249 a.a.
NCBI ID   WP_159340924.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain EU01     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 373004..383753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQY29_RS01940 (GQY29_01940) - 373327..374559 (-) 1233 WP_011225367.1 cysteine desulfurase -
  GQY29_RS01945 (GQY29_01945) sufD 374613..375875 (-) 1263 WP_011680669.1 Fe-S cluster assembly protein SufD -
  GQY29_RS01950 (GQY29_01950) sufC 375912..376682 (-) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  GQY29_RS01955 (GQY29_01955) - 376843..378000 (-) 1158 WP_014621088.1 MraY family glycosyltransferase -
  GQY29_RS01960 (GQY29_01960) mecA 378004..378753 (-) 750 WP_159340924.1 adaptor protein MecA Regulator
  GQY29_RS01970 (GQY29_01970) - 379403..380257 (-) 855 WP_014621086.1 undecaprenyl-diphosphate phosphatase -
  GQY29_RS01975 (GQY29_01975) - 380460..382010 (+) 1551 WP_159340926.1 ABC transporter substrate-binding protein/permease -
  GQY29_RS01980 (GQY29_01980) - 382010..382750 (+) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  GQY29_RS11085 (GQY29_01985) - 382837..382944 (-) 108 WP_011226802.1 LPXTG cell wall anchor domain-containing protein -
  GQY29_RS10280 - 383031..383201 (-) 171 WP_011680664.1 hypothetical protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29097.58 Da        Isoelectric Point: 4.0624

>NTDB_id=411375 GQY29_RS01960 WP_159340924.1 378004..378753(-) (mecA) [Streptococcus thermophilus strain EU01]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTGPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYVTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=411375 GQY29_RS01960 WP_159340924.1 378004..378753(-) (mecA) [Streptococcus thermophilus strain EU01]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGGGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATGTGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

98.795

100

0.988
  mecA Streptococcus thermophilus LMG 18311

98.795

100

0.988
  mecA Streptococcus mutans UA159

57.377

97.992

0.562
  mecA Streptococcus pneumoniae Rx1

45.783

100

0.458
  mecA Streptococcus pneumoniae D39

45.783

100

0.458
  mecA Streptococcus pneumoniae R6

45.783

100

0.458
  mecA Streptococcus pneumoniae TIGR4

45.783

100

0.458

Multiple sequence alignment