Detailed information NTG0041098

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SGPB_RS10295
• Genome accession: NC_015600
• Coordinates: 2097975..2099240 (+)
• Length: 421 a.a.
• NCBI ID: WP_013852370.1
• Uniprot ID: A0AAE6YQ67
• Organism: Streptococcus pasteurianus ATCC 43144
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2092975..2104240

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGPB_RS10270 (SGPB_2023)	-	2093442..2096036 (+)	2595	WP_013852369.1	YfhO family protein	-
SGPB_RS11780	-	2096475..2096812 (+)	338	Protein_2039	helix-turn-helix domain-containing protein	-
SGPB_RS10290 (SGPB_2024)	rlmH	2097285..2097764 (-)	480	WP_003067023.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SGPB_RS10295 (SGPB_2025)	htrA	2097975..2099240 (+)	1266	WP_013852370.1	S1C family serine protease	Regulator
SGPB_RS10300 (SGPB_2026)	spo0J	2099300..2100076 (+)	777	WP_003067028.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 43814.70 Da
• Isoelectric Point: 4.1803

>NTDB_id=41098 SGPB_RS10295 WP_013852370.1 2097975..2099240(+) (htrA) [Streptococcus pasteurianus ATCC 43144]
MKKIKLPKLPKLPKFNYKNWLKPLGVILVGFIAGIAGTILVLNMAGISITNVSGSSTKTTTSSVSYSNSNDTTKAVEKVQ
DAVVSVINYKSDSSSSASDLYNQMFGNDSDSSSNSSSTDDLTVYSEGSGVIYKKDGDSAYVVTNNHVIDGAEQIEIMLAN
GTKVVGELVGADTYSDIAVVKISSDNVSTVAEFADSDKLTVGETAIAIGSPLGTEYANSVTQGIVSSLSRTVTMTNDDGE
TISTNAIQTDAAINPGNSGGALINIEGQVIGINSSKISSTSSSGESVEGMGFAIPSNDVVSIINQLEENGQVIRPALGIS
MINLSDLSTNAIAQLNIPTSVTSGVVVAAVQSGMPAEGNLEQYDVITAIDDKEVTSTSDLQSILYTHSVGDSVKVTFYRG
TDKKTATIELTKTTQDLSSSN

Nucleotide

• Length: 1266 bp

>NTDB_id=41098 SGPB_RS10295 WP_013852370.1 2097975..2099240(+) (htrA) [Streptococcus pasteurianus ATCC 43144]
GTGAAAAAAATAAAATTACCAAAATTACCAAAGTTACCAAAATTTAATTACAAAAATTGGTTAAAACCATTGGGTGTCAT
TTTAGTCGGCTTTATAGCTGGTATCGCAGGTACAATACTCGTCCTAAACATGGCAGGTATTTCAATCACTAACGTCAGTG
GTTCAAGTACAAAAACAACAACAAGTAGCGTAAGCTATTCTAACTCTAACGATACAACAAAAGCTGTGGAAAAAGTTCAA
GACGCGGTTGTATCTGTTATTAACTACAAATCAGACTCGTCATCTTCTGCAAGTGACCTCTACAATCAAATGTTTGGCAA
TGACTCAGACAGTAGTAGCAATTCAAGCTCTACAGATGATTTGACTGTTTACAGTGAGGGGTCTGGGGTTATTTACAAAA
AAGATGGTGATTCTGCCTATGTCGTCACTAACAATCACGTTATTGATGGTGCCGAACAAATTGAAATCATGCTTGCTAAT
GGAACAAAAGTTGTTGGTGAGCTAGTCGGAGCAGATACTTATTCAGATATTGCTGTTGTTAAAATTTCTTCTGACAATGT
ATCTACAGTTGCTGAATTTGCCGATTCTGATAAATTGACTGTCGGTGAAACTGCTATCGCTATTGGTAGCCCACTTGGTA
CTGAATATGCTAACTCTGTAACACAAGGTATTGTCTCAAGTCTTAGCCGTACAGTAACCATGACAAATGATGATGGTGAA
ACTATCTCAACAAATGCTATCCAAACAGATGCAGCAATTAACCCAGGTAACTCTGGTGGTGCTTTAATTAACATTGAAGG
ACAAGTTATCGGTATCAATTCAAGTAAGATTTCATCTACATCAAGTTCTGGTGAATCTGTCGAAGGTATGGGATTTGCCA
TTCCATCTAACGATGTTGTATCCATTATTAACCAATTGGAAGAAAATGGGCAAGTTATCCGCCCAGCACTTGGTATTTCA
ATGATAAACTTGAGCGATCTTTCAACTAATGCAATTGCTCAACTTAACATTCCAACAAGTGTAACAAGCGGTGTCGTTGT
TGCCGCTGTTCAATCTGGTATGCCTGCTGAAGGTAATCTCGAACAGTACGATGTCATCACAGCTATTGACGACAAAGAAG
TAACATCTACTTCAGATCTTCAAAGTATTCTTTATACTCATTCTGTTGGTGACTCTGTCAAAGTAACCTTCTACCGTGGA
ACTGATAAGAAAACAGCTACAATTGAATTAACTAAGACAACGCAAGATTTATCTTCCTCAAACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (315-410)

• Trypsin-like peptidase domain (Trypsin_2) (127-272)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	64.938	96.2	0.625
htrA	Streptococcus gordonii str. Challis substr. CH1	59.804	96.912	0.58
htrA	Streptococcus pneumoniae D39	57.664	97.625	0.563
htrA	Streptococcus pneumoniae TIGR4	57.664	97.625	0.563
htrA	Streptococcus mitis NCTC 12261	57.664	97.625	0.563
htrA	Streptococcus pneumoniae R6	57.664	97.625	0.563
htrA	Streptococcus pneumoniae Rx1	57.664	97.625	0.563