Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   GQR93_RS01065 Genome accession   NZ_CP047121
Coordinates   232002..234167 (+) Length   721 a.a.
NCBI ID   WP_003551455.1    Uniprot ID   A0A6P1E312
Organism   Lentilactobacillus hilgardii strain FLUB     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 227002..239167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQR93_RS01035 (GQR93_01035) - 227059..228330 (+) 1272 WP_003551423.1 dihydroorotase -
  GQR93_RS01040 (GQR93_01040) - 228456..229025 (-) 570 WP_003551425.1 NUDIX hydrolase -
  GQR93_RS01045 (GQR93_01045) - 229593..230240 (-) 648 WP_035444223.1 helix-turn-helix transcriptional regulator -
  GQR93_RS01050 (GQR93_01050) - 230602..230775 (+) 174 WP_155114970.1 hypothetical protein -
  GQR93_RS01055 (GQR93_01055) - 230792..231421 (-) 630 WP_003551433.1 helix-turn-helix transcriptional regulator -
  GQR93_RS01060 (GQR93_01060) - 231734..231889 (+) 156 WP_159298618.1 hypothetical protein -
  GQR93_RS01065 (GQR93_01065) comA 232002..234167 (+) 2166 WP_003551455.1 peptide cleavage/export ABC transporter Regulator
  GQR93_RS01070 (GQR93_01070) - 234171..234662 (+) 492 WP_035444224.1 hypothetical protein -
  GQR93_RS01075 (GQR93_01075) - 234852..234998 (+) 147 WP_003551458.1 hypothetical protein -
  GQR93_RS01080 (GQR93_01080) - 235124..235294 (+) 171 WP_155114971.1 hypothetical protein -
  GQR93_RS01085 (GQR93_01085) - 235341..235484 (+) 144 WP_003551462.1 hypothetical protein -
  GQR93_RS01090 (GQR93_01090) - 235496..235693 (+) 198 WP_003551464.1 hypothetical protein -
  GQR93_RS01095 (GQR93_01095) - 235964..236278 (-) 315 WP_003551466.1 multidrug efflux SMR transporter -
  GQR93_RS01100 (GQR93_01100) - 236452..236901 (-) 450 WP_003551468.1 DUF3021 domain-containing protein -
  GQR93_RS01105 (GQR93_01105) - 236898..237335 (-) 438 WP_003551470.1 LytTR family DNA-binding domain-containing protein -
  GQR93_RS01110 (GQR93_01110) - 237517..238683 (-) 1167 WP_003551474.1 phosphoglycerate dehydrogenase -

Sequence

Protein


Download         Length: 721 a.a.        Molecular weight: 80732.40 Da        Isoelectric Point: 9.5167

>NTDB_id=410778 GQR93_RS01065 WP_003551455.1 232002..234167(+) (comA) [Lentilactobacillus hilgardii strain FLUB]
MFKKRYYVHQLDETDCGAAALAMILKYYHSDISIAKIRGVAQTDKSGTTALGLINAAEHFKLKTQAIKTDISFFKSNDRK
EILVPFIAHINKNHGLLHYVVVLKVRKDDLVIADPDPSIGITKLTYTEFAKIWTGIAVFMAPGPTYVNIKDNNDSLWQTA
KLLLKQKQIIATVVISTFLSTFITIVGALFLQKIVDSYVIDGMTTTLTTAAICLFFAYVFHGIFNYFQGYLSTILGQRLS
IDVLLSYILHLFKLPVSFFETRKTGEITSRFSDANNIILTLARTAISTLLNFGTIIVIGIVLMVISMKLFLLSMISVPIY
AAIIFSFYKLFEKWNNESMEQNALLSSQMIEDLHGIESIKSLNIENKMYDTIDTRFVKTLKADYAYSIASVTQAALKDVA
ELVITLAILYFGSLMAIKGQISLGQLVAFNSLMGYFLGPVEAIINLQNDLQNAKVANKRLNQVLLAPVEEKQKCPMALRE
NDLADQTEFSKVSFEYKYGQSILKNINLKIKRNESVAIVGFSGSGKTTLAKLLVNFYKPITGKVLINGQDIRFVTQKDLR
NYVTYLPQTPFIFSGSVIENIALGLRKTPNMETIIRAAKLAEIHKDIEKLPNGYMTNLSENSGLSGGQMQRIAVARAIIS
DAPVMIFDESTSNLDLLTEKRILNNLMGIKNKTLIFIAHRLEVARKADRIIVMNDGQIIENGTHKDLINEHGNYYQLLQE
A

Nucleotide


Download         Length: 2166 bp        

>NTDB_id=410778 GQR93_RS01065 WP_003551455.1 232002..234167(+) (comA) [Lentilactobacillus hilgardii strain FLUB]
ATGTTTAAAAAACGTTATTATGTTCATCAATTAGATGAAACGGATTGTGGTGCTGCGGCATTGGCAATGATTTTAAAATA
TTATCATTCAGATATTTCGATTGCGAAAATTCGTGGTGTAGCACAAACCGATAAGAGTGGCACAACCGCTTTAGGGTTAA
TAAATGCTGCCGAGCATTTTAAGTTAAAAACTCAAGCAATTAAAACTGATATTTCGTTTTTCAAGAGTAATGACCGCAAA
GAAATACTAGTACCATTTATTGCTCACATTAATAAGAATCATGGTCTATTGCACTATGTAGTTGTTTTAAAAGTCCGAAA
AGATGACTTAGTCATTGCTGATCCAGATCCCAGTATCGGAATCACTAAATTGACTTATACCGAATTCGCTAAGATATGGA
CTGGAATTGCAGTTTTTATGGCACCAGGACCAACTTACGTCAATATTAAAGATAATAATGATAGTTTGTGGCAAACAGCT
AAGCTTCTGTTGAAACAAAAACAAATTATTGCAACAGTTGTTATATCGACATTTTTATCGACGTTCATTACAATTGTTGG
AGCCCTCTTTCTACAAAAAATTGTTGATTCCTATGTTATTGATGGTATGACAACAACTCTAACAACAGCGGCAATTTGTC
TTTTTTTTGCTTATGTTTTCCATGGAATCTTTAACTATTTCCAAGGTTATTTATCAACAATCCTTGGTCAACGCCTTTCG
ATTGATGTTTTGCTAAGCTATATTCTCCATCTATTCAAGTTACCGGTATCTTTCTTTGAGACTAGGAAGACTGGCGAGAT
AACTTCTAGATTTTCAGACGCTAACAATATTATTTTAACGTTAGCGAGAACGGCTATTTCTACATTGCTTAACTTTGGAA
CCATTATTGTGATTGGAATTGTATTAATGGTAATTAGTATGAAACTTTTCTTGTTATCAATGATTTCAGTTCCAATTTAT
GCTGCAATTATTTTCTCATTCTATAAACTCTTTGAGAAATGGAATAACGAAAGTATGGAACAAAACGCATTACTTAGTTC
TCAGATGATTGAAGATCTACATGGAATTGAGTCAATTAAATCCTTAAACATTGAAAATAAAATGTACGATACAATTGACA
CAAGATTCGTTAAGACTTTAAAAGCCGATTATGCTTACAGCATTGCCAGCGTCACTCAAGCGGCATTGAAAGATGTAGCT
GAATTAGTGATCACGTTGGCAATTCTTTACTTTGGATCACTAATGGCCATCAAAGGTCAAATCTCCTTGGGGCAATTGGT
TGCTTTTAATTCCCTGATGGGCTATTTTTTAGGCCCAGTTGAAGCGATCATTAATTTACAAAATGATCTTCAAAATGCCA
AGGTGGCTAATAAGCGGCTTAACCAGGTTCTACTGGCACCTGTGGAAGAAAAACAAAAATGTCCGATGGCCTTGAGGGAG
AATGATCTAGCTGATCAAACCGAGTTTTCAAAGGTTTCTTTCGAGTATAAGTATGGACAATCAATTTTAAAGAATATTAA
TTTAAAAATTAAACGTAATGAATCCGTGGCAATTGTTGGATTTAGCGGTTCTGGAAAGACAACACTGGCCAAGTTATTAG
TTAACTTTTACAAGCCAATTACCGGAAAAGTGTTGATCAATGGACAAGATATTAGGTTTGTAACCCAAAAGGACCTCAGA
AATTATGTCACTTATTTACCACAAACGCCTTTTATTTTTTCGGGTTCGGTTATTGAGAACATTGCCTTAGGATTACGTAA
GACACCTAATATGGAAACCATTATTAGAGCAGCAAAGTTAGCTGAAATTCATAAAGATATTGAAAAATTGCCCAACGGTT
ATATGACGAATTTGTCGGAAAATTCAGGGCTATCCGGCGGTCAAATGCAGCGAATTGCAGTAGCTAGGGCAATTATCAGC
GATGCACCAGTGATGATTTTTGATGAATCAACTAGTAATTTAGATTTATTAACCGAAAAAAGAATTTTAAATAATTTAAT
GGGGATAAAGAATAAGACGCTGATCTTTATTGCTCATCGTCTGGAAGTAGCTCGAAAAGCGGATCGGATTATTGTAATGA
ATGATGGTCAAATCATTGAAAATGGAACGCATAAAGATCTGATTAATGAACATGGTAACTATTATCAATTGCTGCAGGAG
GCCTAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(5-144)

ABC transporter (ABC_tran)

(503-652)

ABC transporter transmembrane region (ABC_membrane)

(173-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6P1E312

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

48.266

100

0.483
  comA Streptococcus mitis SK321

47.989

100

0.48
  comA Streptococcus gordonii str. Challis substr. CH1

47.772

99.584

0.476
  comA Streptococcus pneumoniae R6

47.573

100

0.476
  comA Streptococcus pneumoniae Rx1

47.573

100

0.476
  comA Streptococcus pneumoniae D39

47.573

100

0.476
  comA Streptococcus pneumoniae TIGR4

47.434

100

0.474
  comA/nlmT Streptococcus mutans UA159

46.047

100

0.46

Multiple sequence alignment