Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   SGPB_RS02215 Genome accession   NC_015600
Coordinates   415061..416941 (+) Length   626 a.a.
NCBI ID   WP_003063531.1    Uniprot ID   -
Organism   Streptococcus pasteurianus ATCC 43144     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 410061..421941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGPB_RS02200 (SGPB_0392) fmt 412039..412974 (+) 936 WP_013851524.1 methionyl-tRNA formyltransferase -
  SGPB_RS02205 (SGPB_0393) rsmB 412964..414286 (+) 1323 WP_013851525.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SGPB_RS02210 (SGPB_0394) - 414324..415061 (+) 738 WP_003063530.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SGPB_RS02215 (SGPB_0395) pknB 415061..416941 (+) 1881 WP_003063531.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SGPB_RS02220 (SGPB_0396) liaF 417036..417731 (+) 696 WP_003063532.1 cell wall-active antibiotics response protein LiaF -
  SGPB_RS02225 (SGPB_0397) - 417728..418753 (+) 1026 WP_013851526.1 sensor histidine kinase -
  SGPB_RS02230 (SGPB_0398) - 418737..419381 (+) 645 WP_013851527.1 response regulator transcription factor -
  SGPB_RS02235 (SGPB_0399) - 419499..420899 (+) 1401 WP_013851528.1 Cof-type HAD-IIB family hydrolase -
  SGPB_RS02240 (SGPB_0400) - 420899..421255 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 67866.10 Da        Isoelectric Point: 5.0714

>NTDB_id=41064 SGPB_RS02215 WP_003063531.1 415061..416941(+) (pknB) [Streptococcus pasteurianus ATCC 43144]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSREPKLVFEDTENTKTLPKVTTSTSVPSTTEQLLKKQKAAKED
KVATENQATKAKTKKKKSRRMFGTLMKIFFAVVIVAIAIFTYLTLTSPSTVSVPDVAGSSLSEAKTTIKSSGLKVGTVHK
VSSDTVESGYVIKTSPTAGSSKKEGSSIDIYVSKGSSGFKIKDYTGQDYQTAVKDLVNNYGVSESQIEIEEVSTSDYDEG
VIISQTPSEGETFKVSGDDKITFKVATESTVTMPNLTGYTYSEAIAALTALGVSSSHITVYQADPNSSTGYVQVSSPSST
ATITAQTPYYGETLSGNVILYLAADEEESSQAPSSSSSEPSESKESSSSSSSTDDSSSSTESSNEQ

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=41064 SGPB_RS02215 WP_003063531.1 415061..416941(+) (pknB) [Streptococcus pasteurianus ATCC 43144]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTGGCAAAAGATCTCATTCTTGATAATGAAGAAGTGGCCATTAAGGTGCTTCGGACGAATTATCAGACTGATCAAATTG
CCGTAGCGCGTTTCCAACGGGAAGCGCGTGCCATGGCAGAACTGAACCATCCAAATATCGTCTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGATCGGACTTGAAAAAATACATTCAAGATCATGCTCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTATCTGCGATGACTTTGGCGCATCAACAAGGGATTGTTC
ACCGTGATTTAAAACCACAAAATATCTTATTAACCAAAGATGGAACTGTTAAAGTTACTGACTTTGGTATCGCCGTAGCC
TTTGCCGAAACAAGTTTAACGCAAACCAATTCAATGCTAGGTAGTGTGCATTATTTATCGCCTGAACAAGCACGTGGTTC
AAAAGCGACTGTTCAAAGTGATATTTACGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATCCCATATGATG
GTGATTCAGCTGTTACCATTGCGCTTCAACATTTCCAAAAACCACTTCCTTCCATCATTGATGAGAATAAGAATGTTCCA
CAAGCACTAGAAAATGTTGTTATCAAGGCGACTGCAAAACGTTTAAGTGACCGTTATGCATCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCTTACAACCGTAGCCGTGAACCTAAACTTGTTTTTGAAGATACTGAAAATACAAAGACAC
TTCCAAAGGTAACAACATCAACATCTGTTCCTTCAACGACAGAACAACTCTTGAAGAAACAAAAAGCAGCTAAAGAAGAT
AAAGTAGCAACAGAAAACCAAGCGACTAAAGCTAAAACAAAGAAGAAAAAATCACGTCGTATGTTCGGCACGTTAATGAA
AATCTTTTTTGCAGTTGTGATTGTAGCTATTGCTATCTTTACTTACTTGACGTTGACCTCCCCATCAACCGTGAGTGTTC
CAGATGTTGCTGGCTCTAGTTTATCAGAAGCAAAAACAACGATAAAATCATCAGGTCTTAAAGTTGGAACCGTTCATAAA
GTATCAAGTGATACCGTTGAGAGTGGTTACGTTATTAAGACAAGTCCAACTGCTGGTTCATCGAAAAAAGAAGGGTCATC
AATTGATATTTACGTATCAAAAGGCTCATCAGGATTCAAGATAAAAGACTATACAGGTCAAGATTATCAAACAGCCGTTA
AAGATTTGGTTAATAATTACGGTGTTTCAGAGTCGCAAATTGAGATTGAAGAAGTCTCAACGTCAGACTATGACGAAGGT
GTTATCATCAGTCAAACGCCTAGTGAAGGTGAAACCTTTAAGGTAAGTGGTGATGATAAGATTACCTTTAAAGTAGCCAC
AGAAAGTACAGTGACAATGCCGAATTTGACAGGCTATACTTATTCAGAAGCTATTGCTGCCTTAACAGCTCTAGGCGTGT
CAAGTTCACATATTACGGTTTATCAAGCCGACCCAAATTCTTCTACGGGTTATGTGCAAGTAAGCTCACCATCTTCAACA
GCAACTATCACTGCTCAAACACCTTACTATGGTGAAACGTTAAGTGGTAACGTGATACTTTACCTAGCAGCTGATGAAGA
AGAAAGCTCACAGGCGCCATCGTCATCAAGTTCAGAACCCTCTGAATCAAAAGAATCAAGTTCATCAAGCAGCAGTACGG
ATGATAGTAGCTCATCAACAGAATCAAGTAATGAACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(440-506)

PASTA domain (PASTA)

(511-575)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

68.313

93.77

0.641
  stkP/pknB Streptococcus salivarius strain HSISS4

64.646

94.888

0.613
  stkP Streptococcus pneumoniae TIGR4

54.452

93.291

0.508
  stkP Streptococcus pneumoniae D39

54.281

93.291

0.506
  stkP Streptococcus pneumoniae R6

54.281

93.291

0.506
  stkP Streptococcus pneumoniae Rx1

54.11

93.291

0.505

Multiple sequence alignment