Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GPZ88_RS06110 Genome accession   NZ_CP046919
Coordinates   1180604..1181365 (+) Length   253 a.a.
NCBI ID   WP_074603782.1    Uniprot ID   A0AAE8HMA3
Organism   Streptococcus ruminicola strain CNU_G2     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1175604..1186365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPZ88_RS06095 (GPZ88_06075) - 1176009..1177580 (-) 1572 WP_074965543.1 ABC transporter permease subunit -
  GPZ88_RS06100 (GPZ88_06080) - 1177717..1179609 (+) 1893 WP_206282127.1 DUF2207 domain-containing protein -
  GPZ88_RS06105 (GPZ88_06085) - 1179661..1180500 (+) 840 WP_039696026.1 undecaprenyl-diphosphate phosphatase -
  GPZ88_RS06110 (GPZ88_06090) mecA 1180604..1181365 (+) 762 WP_074603782.1 adaptor protein MecA Regulator
  GPZ88_RS06115 (GPZ88_06095) - 1181367..1182530 (+) 1164 WP_039696028.1 glycosyltransferase family 4 protein -
  GPZ88_RS06120 (GPZ88_06100) sufC 1182644..1183414 (+) 771 WP_166043721.1 Fe-S cluster assembly ATPase SufC -
  GPZ88_RS06125 (GPZ88_06105) sufD 1183489..1184751 (+) 1263 WP_014334313.1 Fe-S cluster assembly protein SufD -
  GPZ88_RS06130 (GPZ88_06110) - 1184753..1185985 (+) 1233 WP_166043724.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29090.81 Da        Isoelectric Point: 4.0295

>NTDB_id=409437 GPZ88_RS06110 WP_074603782.1 1180604..1181365(+) (mecA) [Streptococcus ruminicola strain CNU_G2]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMLSKGDTEAHEKLGKIEEMMEGAVEDVLTEHAQQAETEPEEDVNPSDYVH
YVLDFPSLEATVAFAKAIDFPVEASELYKMDGAYYMTVLIDLQNHPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVEKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=409437 GPZ88_RS06110 WP_074603782.1 1180604..1181365(+) (mecA) [Streptococcus ruminicola strain CNU_G2]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGCGGAATGGAGTT
GAAAGACTTCTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAATTGGATTTACCAGATAATT
TCAAAGACAGTGGCATGCTTAGTTTCCGTGTGACACCACGTAAAGACCGCATTGATGTCTTTGTTACCAAATCTGAAATC
AATAAAGATATAAACTTTGAAGATTTAGCAGCTTTTGATGATGTTTCAAACATGTCACCTGAGGAATTTTTCAAGACTTT
AGAGCAGACAATGTTGTCTAAAGGCGACACGGAAGCTCACGAAAAATTAGGTAAGATTGAAGAAATGATGGAAGGTGCTG
TTGAAGATGTTCTGACAGAACATGCCCAACAAGCTGAAACTGAACCGGAAGAAGATGTGAATCCATCAGATTATGTTCAC
TATGTCTTGGATTTTCCAAGCTTAGAAGCTACTGTTGCTTTTGCTAAGGCTATTGATTTTCCAGTTGAAGCTTCAGAGCT
TTATAAGATGGATGGGGCTTACTACATGACAGTTCTCATTGATTTGCAAAATCACCCATCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACTCGTGCTTATTTACAAGAGCATGCGGTTGAATTATTGACG
GATGATGCCGTCGAAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.6

98.814

0.668
  mecA Streptococcus thermophilus LMD-9

59.036

98.419

0.581
  mecA Streptococcus thermophilus LMG 18311

58.233

98.419

0.573
  mecA Streptococcus pneumoniae Rx1

49.02

100

0.494
  mecA Streptococcus pneumoniae D39

49.02

100

0.494
  mecA Streptococcus pneumoniae R6

49.02

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.02

100

0.494

Multiple sequence alignment