Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GP482_RS00350 Genome accession   NZ_CP046875
Coordinates   64510..65271 (+) Length   253 a.a.
NCBI ID   WP_074603782.1    Uniprot ID   A0AAE8HMA3
Organism   Streptococcus ruminicola strain CNU_77-61     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 59510..70271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GP482_RS00335 (GP482_00335) - 59915..61486 (-) 1572 WP_039696024.1 ABC transporter permease subunit -
  GP482_RS00340 (GP482_00340) - 61623..63515 (+) 1893 WP_174235029.1 DUF2207 domain-containing protein -
  GP482_RS00345 (GP482_00345) - 63567..64406 (+) 840 WP_039696026.1 undecaprenyl-diphosphate phosphatase -
  GP482_RS00350 (GP482_00350) mecA 64510..65271 (+) 762 WP_074603782.1 adaptor protein MecA Regulator
  GP482_RS00355 (GP482_00355) - 65273..66436 (+) 1164 WP_039696028.1 MraY family glycosyltransferase -
  GP482_RS00360 (GP482_00360) sufC 66550..67320 (+) 771 WP_074561362.1 Fe-S cluster assembly ATPase SufC -
  GP482_RS00365 (GP482_00365) sufD 67395..68657 (+) 1263 WP_074603780.1 Fe-S cluster assembly protein SufD -
  GP482_RS00370 (GP482_00370) - 68659..69891 (+) 1233 WP_074603778.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29090.81 Da        Isoelectric Point: 4.0295

>NTDB_id=409091 GP482_RS00350 WP_074603782.1 64510..65271(+) (mecA) [Streptococcus ruminicola strain CNU_77-61]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMLSKGDTEAHEKLGKIEEMMEGAVEDVLTEHAQQAETEPEEDVNPSDYVH
YVLDFPSLEATVAFAKAIDFPVEASELYKMDGAYYMTVLIDLQNHPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVEKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=409091 GP482_RS00350 WP_074603782.1 64510..65271(+) (mecA) [Streptococcus ruminicola strain CNU_77-61]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGCGGAATGGAGTT
GAAAGACTTCTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAATTGGATTTACCAGATAATT
TCAAAGACAGTGGCATGCTTAGTTTCCGTGTGACACCACGTAAAGACCGCATTGATGTCTTTGTTACCAAATCTGAAATC
AATAAAGATATAAACTTTGAAGATTTAGCAGCTTTTGATGATGTTTCAAACATGTCACCTGAGGAATTTTTCAAGACTTT
AGAGCAGACAATGTTGTCTAAAGGCGACACGGAAGCTCACGAAAAATTAGGTAAGATTGAAGAAATGATGGAAGGTGCTG
TTGAAGATGTTCTGACAGAACATGCTCAACAAGCTGAGACTGAACCGGAAGAAGATGTGAATCCATCAGATTATGTTCAC
TATGTCTTGGATTTTCCAAGCTTAGAAGCTACTGTTGCTTTTGCTAAGGCTATTGATTTTCCAGTTGAAGCTTCAGAGCT
TTATAAGATGGATGGGGCTTACTACATGACAGTTCTCATTGATTTGCAAAATCACCCATCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACTCGTGCTTATTTACAAGAGCATGCGGTTGAATTATTGACG
GATGATGCCGTCGAAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.6

98.814

0.668
  mecA Streptococcus thermophilus LMD-9

59.036

98.419

0.581
  mecA Streptococcus thermophilus LMG 18311

58.233

98.419

0.573
  mecA Streptococcus pneumoniae Rx1

49.02

100

0.494
  mecA Streptococcus pneumoniae D39

49.02

100

0.494
  mecA Streptococcus pneumoniae R6

49.02

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.02

100

0.494

Multiple sequence alignment