Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   H0A38_RS09810 Genome accession   NZ_CP059048
Coordinates   2025395..2027278 (-) Length   627 a.a.
NCBI ID   WP_129881082.1    Uniprot ID   -
Organism   Lactococcus lactis strain LAC460     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2020395..2032278
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0A38_RS09780 (H0A38_09725) - 2020792..2021472 (-) 681 WP_017864968.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
  H0A38_RS09785 (H0A38_09730) macP 2021504..2021782 (-) 279 WP_003130796.1 cell wall synthase accessory phosphoprotein MacP -
  H0A38_RS09790 (H0A38_09735) - 2021775..2022359 (-) 585 WP_033899834.1 NUDIX hydrolase -
  H0A38_RS09795 (H0A38_09740) glmU 2022464..2023840 (-) 1377 WP_226319333.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  H0A38_RS09800 (H0A38_09745) proC 2024073..2024861 (+) 789 WP_033899830.1 pyrroline-5-carboxylate reductase -
  H0A38_RS09805 (H0A38_09750) rpsO 2024940..2025209 (-) 270 WP_010906184.1 30S ribosomal protein S15 -
  H0A38_RS09810 (H0A38_09755) stkP/pknB 2025395..2027278 (-) 1884 WP_129881082.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  H0A38_RS09815 (H0A38_09760) - 2027278..2028054 (-) 777 WP_058204010.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  H0A38_RS09820 (H0A38_09765) rsmB 2028134..2029408 (-) 1275 WP_014570715.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  H0A38_RS09825 (H0A38_09770) - 2029607..2030113 (-) 507 WP_012898444.1 Asp23/Gls24 family envelope stress response protein -
  H0A38_RS09830 (H0A38_09775) - 2030134..2030322 (-) 189 WP_012898445.1 DUF2273 domain-containing protein -
  H0A38_RS09835 (H0A38_09780) amaP 2030333..2030893 (-) 561 WP_010906186.1 alkaline shock response membrane anchor protein AmaP -
  H0A38_RS09840 (H0A38_09785) - 2030921..2031163 (-) 243 WP_003131476.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 67825.84 Da        Isoelectric Point: 4.7347

>NTDB_id=408371 H0A38_RS09810 WP_129881082.1 2025395..2027278(-) (stkP/pknB) [Lactococcus lactis strain LAC460]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEDNDSQTD
EKAASSEVGNKNKKSKKGLIIGLIILLLVVGGATLAWVVSTPTNVKIPNVTNSTLSQAKSKIKDAKLKVGTVHKQQSSTV
AEGNVIKTDPTSGTTVRSNSSVDIYVSTGNEDIIKMKDFVGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSEKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTNQQADGYVYSVYPNVGT
SVDPTQEIVVTYSVYTAPSSSSTTSESTPTPETSSSTTSSTSSSTTSQPSTDNNNSSKEGSTTSSSS

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=408371 H0A38_RS09810 WP_129881082.1 2025395..2027278(-) (stkP/pknB) [Lactococcus lactis strain LAC460]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGCGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAACGATGATATCG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGATGTTGGT
GAATTTGAAAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTTAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCAACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAACTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCTGCAGTTGCTATCGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATCAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTTGTCATTAAAGCTACAGCGAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGATCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGACCATGATGAAACAAAAA
TTATGCCTGCCAATCTAATTAATCCTTATGACACCAAGCCTCTGATTGATAAAAAAGAAGATAATGATTCACAAACAGAT
GAAAAAGCTGCAAGCTCAGAAGTAGGAAATAAAAACAAAAAATCTAAAAAAGGCTTGATTATTGGTCTTATTATCCTTCT
TTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTCTCAACACCAACTAATGTTAAGATACCTAATGTGACAAACTCGA
CACTTAGCCAAGCAAAAAGCAAAATTAAAGATGCAAAACTTAAAGTAGGGACAGTTCATAAACAACAAAGTTCAACGGTT
GCTGAAGGAAATGTTATCAAGACTGATCCAACTAGTGGAACAACCGTGAGATCTAATAGCTCCGTTGATATTTATGTTTC
TACGGGAAATGAAGATATCATCAAAATGAAGGACTTTGTTGGTGAAAAGATTGATGAGGCGATGGCAACATTACTTAAGG
ATTATGGTATTGATGAAAGCCAAGTCACTCAAACTTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATTATTAAACAA
AGCCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGGAGTGAAAAAATTACCTTTGAAGTTTCAAGTGGAAAACAAGTTGA
AGTTCCGGATTATAAACCGAACGGTCAATATATGACTTATTCACAGTATCAAGCTGCCTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGACCCTCAAGCAACAACGAATCAACAAGCTGATGGTTATGTTTACTCAGTGTATCCAAATGTAGGGACA
TCTGTTGATCCAACTCAAGAAATTGTAGTCACTTATAGCGTCTATACTGCTCCAAGTTCAAGTTCAACAACTTCTGAATC
AACACCGACGCCTGAAACTTCATCAAGTACAACTTCAAGTACTTCAAGCTCTACAACAAGTCAGCCGTCAACAGATAACA
ACAATAGCAGCAAAGAAGGTTCAACAACTTCATCAAGTAGTTAA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(365-428)

PASTA domain (PASTA)

(506-573)

PASTA domain (PASTA)

(434-501)

Protein kinase domain (Pkinase)

(12-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

46.423

100

0.466
  pknB Streptococcus mutans UA159

49.265

86.762

0.427
  stkP Streptococcus pneumoniae TIGR4

48.221

80.702

0.389
  stkP Streptococcus pneumoniae D39

48.024

80.702

0.388
  stkP Streptococcus pneumoniae R6

48.024

80.702

0.388
  stkP Streptococcus pneumoniae Rx1

47.826

80.702

0.386

Multiple sequence alignment