Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GPA00_RS04705 Genome accession   NZ_CP046629
Coordinates   928712..929473 (+) Length   253 a.a.
NCBI ID   WP_024344759.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU G6     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 923712..934473
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPA00_RS04690 (GPA00_04690) - 924118..925689 (-) 1572 WP_021141661.1 ABC transporter permease subunit -
  GPA00_RS04695 (GPA00_04695) - 925826..927718 (+) 1893 WP_157327683.1 DUF2207 domain-containing protein -
  GPA00_RS04700 (GPA00_04700) - 927770..928609 (+) 840 WP_003067592.1 undecaprenyl-diphosphate phosphatase -
  GPA00_RS04705 (GPA00_04705) mecA 928712..929473 (+) 762 WP_024344759.1 adaptor protein MecA Regulator
  GPA00_RS04710 (GPA00_04710) - 929475..930638 (+) 1164 WP_024344760.1 glycosyltransferase family 4 protein -
  GPA00_RS04715 (GPA00_04715) sufC 930760..931530 (+) 771 WP_021141665.1 Fe-S cluster assembly ATPase SufC -
  GPA00_RS04720 (GPA00_04720) sufD 931608..932870 (+) 1263 WP_157327685.1 Fe-S cluster assembly protein SufD -
  GPA00_RS04725 (GPA00_04725) - 932872..934104 (+) 1233 WP_157327687.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29046.89 Da        Isoelectric Point: 4.0442

>NTDB_id=406301 GPA00_RS04705 WP_024344759.1 928712..929473(+) (mecA) [Streptococcus equinus strain CNU G6]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMMAKGDTEAHEKLGKIEEMMEGAVEEVLTENAKQADTEPEEDVKPSDYVH
YVLDFPSLEATVAFSKAIDFPVEASELYKMDGAYYMTILLDLQNQPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVAKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=406301 GPA00_RS04705 WP_024344759.1 928712..929473(+) (mecA) [Streptococcus equinus strain CNU G6]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGAGGAATGGAGTT
AAAAGACTTTTTGATTCCGCAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAGTTAGATTTACCAGATAATT
TCAAAGATAGCGGCATGCTTAGTTTTCGTGTGACACCACGTAAAGACCGTCTTGATGTATTTGTCACAAAATCAGAAATT
AACAAAGATATCAATTTTGAAGATTTAGCTGCATTTGATGATGTGTCTAACATGTCACCAGAAGAATTCTTTAAAACGCT
AGAACAAACGATGATGGCTAAAGGTGACACTGAAGCTCATGAAAAATTAGGTAAAATCGAAGAAATGATGGAAGGTGCTG
TTGAAGAAGTCTTGACAGAGAACGCTAAGCAAGCAGATACAGAACCTGAAGAAGATGTAAAACCATCTGATTATGTTCAT
TACGTCTTAGATTTTCCAAGTTTAGAAGCAACAGTTGCTTTTTCTAAAGCGATTGATTTTCCTGTGGAAGCTTCTGAACT
TTACAAGATGGACGGCGCTTATTACATGACAATTTTGCTTGATTTGCAGAACCAACCTTCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACTCGTGCTTACTTGCAAGAGCACGCAGTTGAACTATTGACG
GATGATGCCGTTGCAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.4

98.814

0.656
  mecA Streptococcus thermophilus LMD-9

60.643

98.419

0.597
  mecA Streptococcus thermophilus LMG 18311

59.839

98.419

0.589
  mecA Streptococcus pneumoniae Rx1

49.02

100

0.494
  mecA Streptococcus pneumoniae D39

49.02

100

0.494
  mecA Streptococcus pneumoniae R6

49.02

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.02

100

0.494

Multiple sequence alignment