Detailed information NTG0406279

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: GPA00_RS02065
• Genome accession: NZ_CP046629
• Coordinates: 410558..411289 (-)
• Length: 243 a.a.
• NCBI ID: WP_157327342.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU G6
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 405558..416289

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPA00_RS02035 (GPA00_02035)	comD/comD3	406266..407639 (-)	1374	WP_157327331.1	GHKL domain-containing protein	Regulator
GPA00_RS02040 (GPA00_02040)	-	408003..408296 (-)	294	WP_157327332.1	bacteriocin immunity protein	-
GPA00_RS02045 (GPA00_02045)	-	408324..408629 (-)	306	WP_157327334.1	bacteriocin immunity protein	-
GPA00_RS02050 (GPA00_02050)	-	408642..408791 (-)	150	WP_157327336.1	bacteriocin	-
GPA00_RS02055 (GPA00_02055)	comC/comC1	409053..409205 (+)	153	WP_157327338.1	hypothetical protein	Regulator
GPA00_RS02060 (GPA00_02060)	-	409228..410553 (-)	1326	WP_157327340.1	sensor histidine kinase	-
GPA00_RS02065 (GPA00_02065)	comE/comE1	410558..411289 (-)	732	WP_157327342.1	response regulator transcription factor	Regulator
GPA00_RS02070 (GPA00_02070)	-	412319..413611 (-)	1293	WP_157327344.1	glycosyltransferase family 2 protein	-
GPA00_RS02075 (GPA00_02075)	-	413614..413913 (-)	300	WP_157327346.1	DUF3884 family protein	-
GPA00_RS02080 (GPA00_02080)	-	413939..414121 (-)	183	WP_157327348.1	hypothetical protein	-
GPA00_RS02085 (GPA00_02085)	-	414187..414411 (-)	225	WP_039697856.1	helix-turn-helix domain-containing protein	-
GPA00_RS02090 (GPA00_02090)	-	414401..415402 (-)	1002	WP_157327350.1	thioredoxin fold domain-containing protein	-
GPA00_RS02095 (GPA00_02095)	-	415993..416181 (-)	189	WP_006531876.1	class IIb bacteriocin, lactobin A/cerein 7B family	-

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 28196.13 Da
• Isoelectric Point: 6.2472

>NTDB_id=406279 GPA00_RS02065 WP_157327342.1 410558..411289(-) (comE/comE1) [Streptococcus equinus strain CNU G6]
MLDIFILEDNITQQFRIERQIETIMERNHWEYQRLEAFAASKDIIKKADGQGNHQVFFLDLEIKGDEKQGLDVARSIREK
DPTAIIVFVTTHSEFMLLTYQSLVGAIDFIDKNMNDEVFGGRIELCLKEALKYQTGSFGENSYLFETAKARIRVAYDDIL
YFETSPTVHRVILHTKTGQTEFYGTIAEVAKSDKRLLKCHRSFVINVNNVTEFDKSTRTAYFENGSYCQVSRDKVKKLMA
EMR

Nucleotide

• Length: 732 bp

>NTDB_id=406279 GPA00_RS02065 WP_157327342.1 410558..411289(-) (comE/comE1) [Streptococcus equinus strain CNU G6]
ATGTTAGATATTTTTATCCTTGAGGATAATATCACGCAACAATTTCGAATTGAACGTCAGATTGAGACAATTATGGAAAG
GAACCACTGGGAGTATCAGCGCTTAGAGGCTTTTGCGGCATCTAAGGATATTATAAAAAAGGCAGATGGGCAGGGAAATC
ACCAGGTTTTCTTTCTTGATTTAGAAATCAAAGGGGATGAAAAGCAAGGCTTAGATGTTGCTAGATCTATTCGTGAAAAA
GATCCGACAGCCATTATCGTCTTTGTGACAACCCATTCTGAGTTTATGCTTCTAACTTATCAATCACTAGTTGGTGCGAT
TGATTTTATTGATAAAAATATGAATGATGAAGTCTTTGGAGGGCGCATTGAATTGTGCTTGAAAGAGGCGTTGAAATATC
AAACTGGTAGTTTTGGTGAGAATTCTTACCTGTTTGAAACAGCAAAAGCAAGAATCCGTGTGGCTTATGATGATATTTTA
TATTTTGAAACATCGCCAACCGTGCACCGTGTGATTTTACACACTAAAACAGGTCAAACAGAGTTTTATGGCACAATTGC
TGAGGTAGCCAAATCAGATAAACGTTTGTTGAAATGTCACCGCTCATTCGTGATTAATGTTAATAATGTCACTGAATTTG
ATAAAAGCACCCGAACAGCTTATTTCGAAAACGGCTCTTACTGCCAAGTCTCAAGAGACAAAGTCAAAAAACTGATGGCA
GAAATGAGGTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-240)

• Response regulator receiver domain (Response_reg) (4-117)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	99.588	100	0.996
comE/blpR	Streptococcus mutans UA159	46.888	99.177	0.465
comE/comE2	Streptococcus equinus JB1	44.628	99.588	0.444