Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GO596_RS01310 Genome accession   NZ_CP046628
Coordinates   261391..262152 (-) Length   253 a.a.
NCBI ID   WP_039691988.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU 77-23     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 256391..267152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO596_RS01290 (GO596_01290) - 256760..257992 (-) 1233 WP_157339078.1 cysteine desulfurase -
  GO596_RS01295 (GO596_01295) sufD 257994..259256 (-) 1263 WP_074629241.1 Fe-S cluster assembly protein SufD -
  GO596_RS01300 (GO596_01300) sufC 259334..260104 (-) 771 WP_003067585.1 Fe-S cluster assembly ATPase SufC -
  GO596_RS01305 (GO596_01305) - 260226..261389 (-) 1164 WP_024344760.1 glycosyltransferase family 4 protein -
  GO596_RS01310 (GO596_01310) mecA 261391..262152 (-) 762 WP_039691988.1 adaptor protein MecA Regulator
  GO596_RS01315 (GO596_01315) - 262255..263094 (-) 840 WP_003067592.1 undecaprenyl-diphosphate phosphatase -
  GO596_RS01320 (GO596_01320) - 263146..265038 (-) 1893 WP_157339079.1 DUF2207 domain-containing protein -
  GO596_RS01325 (GO596_01325) - 265175..266746 (+) 1572 WP_021141661.1 ABC transporter permease subunit -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29055.86 Da        Isoelectric Point: 4.0441

>NTDB_id=406217 GO596_RS01310 WP_039691988.1 261391..262152(-) (mecA) [Streptococcus equinus strain CNU 77-23]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMMAKGDTEAHEKLGKIEEMMEGAVEEVLTEHAKQADTEPEEDVNPSDYVH
YVLDFPSLEATVAFSKAIDFPVEASELYKMDGAYYMTILLDLQNQPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVAKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=406217 GO596_RS01310 WP_039691988.1 261391..262152(-) (mecA) [Streptococcus equinus strain CNU 77-23]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGAGGAATGGAGTT
AAAAGACTTTTTGATTCCGCAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAGTTAGATTTACCAGATAATT
TCAAAGATAGCGGCATGCTTAGCTTTCGTGTGACACCACGTAAAGACCGTCTTGATGTATTTGTCACAAAATCAGAAATT
AACAAAGATATCAATTTTGAAGATTTAGCTGCATTTGACGATGTGTCTAATATGTCACCAGAAGAATTCTTTAAAACGCT
AGAACAAACAATGATGGCTAAAGGTGACACTGAAGCTCATGAAAAATTAGGTAAAATCGAAGAAATGATGGAAGGTGCTG
TTGAAGAAGTCTTGACAGAGCACGCTAAGCAAGCAGATACAGAACCTGAAGAAGATGTAAATCCATCTGATTATGTTCAT
TACGTCTTAGATTTTCCAAGTTTAGAAGCAACAGTTGCTTTTTCTAAAGCGATTGATTTTCCTGTGGAAGCTTCTGAACT
TTACAAGATGGACGGCGCTTATTACATGACAATTTTGCTTGATTTGCAGAACCAACCTTCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACTCGTGCTTACTTGCAAGAGCACGCAGTTGAACTATTGACG
GATGATGCCGTTGCAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.4

98.814

0.656
  mecA Streptococcus thermophilus LMD-9

60.643

98.419

0.597
  mecA Streptococcus thermophilus LMG 18311

59.839

98.419

0.589
  mecA Streptococcus pneumoniae Rx1

49.02

100

0.494
  mecA Streptococcus pneumoniae D39

49.02

100

0.494
  mecA Streptococcus pneumoniae R6

49.02

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.02

100

0.494

Multiple sequence alignment