Detailed information NTG0406192

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: GO995_RS08545
• Genome accession: NZ_CP046624
• Coordinates: 1711545..1713692 (+)
• Length: 715 a.a.
• NCBI ID: WP_157629401.1
• Uniprot ID: -
• Organism: Streptococcus ruminicola strain CNU_G3
• Function: transport of ComC (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1707460..1716303	1711545..1713692	within	0

Gene organization within MGE regions

Location: 1707460..1716303

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO995_RS08515 (GO995_08515)	-	1707765..1708838 (-)	1074	WP_238385871.1	glycosyltransferase family 2 protein	-
GO995_RS08520 (GO995_08520)	-	1709060..1709359 (-)	300	WP_157327346.1	DUF3884 family protein	-
GO995_RS08525 (GO995_08525)	-	1709385..1709567 (-)	183	WP_157327348.1	hypothetical protein	-
GO995_RS08530 (GO995_08530)	-	1709633..1709857 (-)	225	WP_039697856.1	helix-turn-helix domain-containing protein	-
GO995_RS08535 (GO995_08535)	-	1709847..1710845 (-)	999	WP_157629400.1	thioredoxin family protein	-
GO995_RS08540 (GO995_08540)	-	1711075..1711305 (-)	231	WP_074602958.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
GO995_RS08545 (GO995_08545)	comA/nlmT	1711545..1713692 (+)	2148	WP_157629401.1	peptide cleavage/export ABC transporter	Regulator
GO995_RS08550 (GO995_08550)	-	1713702..1715084 (+)	1383	WP_157629402.1	bacteriocin secretion accessory protein	-
GO995_RS08555 (GO995_08555)	-	1715110..1715289 (-)	180	WP_157629403.1	hypothetical protein	-
GO995_RS08560 (GO995_08560)	-	1715629..1716303 (-)	675	WP_133018006.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80114.24 Da
• Isoelectric Point: 8.6397

>NTDB_id=406192 GO995_RS08545 WP_157629401.1 1711545..1713692(+) (comA/nlmT) [Streptococcus ruminicola strain CNU_G3]
MRRYKYVSQIDMRDCGVAALASVAKHYGSHFSLAHLRELAKTNKEGTTALGIVEAAKKIGFETRAVKADIALFEMDDIPY
PCIVHVNKQGKLQHYYVIYKAKKDYLIIGDPDPSVGVTKMAKADFAKEWTGVTIFLAPAASYKPHKDKKNGLMSFLPIIF
KQKSLLTYIILASLLVTLINIVGSYYLQGILDDYIPNQLQSTLGIVSIGLVVTYIMQQIMSFSQQYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNAKLFLITLIALPVYAIII
FAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEETRYRNIDSEFVEYLDKSFTLNKYEAMQASLKQGARLIL
NVAILWYGSRLVMTGNISVGQLITYNTLLSYFTRPMENIINLQTKLQSAKVANKRLNEVYLVSSEFDNKQVIDNPEFLKG
DLVFDDVSYKYGFGRDTLSHIKLRIKEGEKVSLVGVSGSGKTTLAKMMVNFYSPNQGQITLGSYDYKTIDKKVLRQHINY
LPQQSYVFSGSILDNLTLGASDAITQEDIIKACEIAEIRADIEAMPMAYHTELSDGAGLSGGQKQRLAIARALLTKSPVL
ILDEATSGLDVLTEKRVIHNLLALKDKTIIFVAHRLSIAKQTDHVIVLDKGQIIEQGHHEQLMQNPGFYAQLFQE

Nucleotide

• Length: 2148 bp

>NTDB_id=406192 GO995_RS08545 WP_157629401.1 1711545..1713692(+) (comA/nlmT) [Streptococcus ruminicola strain CNU_G3]
ATGAGGAGATACAAATACGTTAGTCAGATTGATATGCGAGATTGTGGGGTAGCTGCTTTAGCTTCAGTCGCTAAACACTA
CGGCTCACATTTTTCACTTGCTCACTTGAGGGAACTGGCTAAGACGAATAAAGAAGGAACAACTGCTCTTGGAATCGTCG
AAGCAGCCAAAAAGATTGGCTTTGAAACACGTGCTGTAAAAGCTGATATAGCACTTTTTGAGATGGATGATATCCCGTAT
CCTTGTATTGTCCATGTGAATAAGCAAGGAAAACTGCAACACTATTATGTCATCTATAAGGCTAAAAAAGATTATCTAAT
CATCGGTGATCCTGACCCAAGTGTGGGAGTCACAAAAATGGCTAAAGCTGATTTTGCCAAAGAATGGACAGGGGTTACGA
TCTTTCTAGCTCCTGCAGCTAGCTATAAACCACATAAGGATAAGAAAAATGGCTTAATGAGTTTTTTGCCAATCATCTTT
AAACAAAAATCACTACTAACATATATAATCCTTGCCAGTCTACTTGTAACCTTGATTAATATTGTCGGCTCTTATTATCT
TCAAGGAATCTTGGACGACTATATTCCCAATCAACTCCAATCCACCCTTGGAATTGTCTCAATCGGCTTGGTCGTGACTT
ACATCATGCAACAGATTATGAGCTTTTCACAACAGTATTTGTTAGTTGTGCTCAGTCAACGTTTGACGATTGATGTCATT
TTATCTTATATTCGTCATATTTTTGAATTGCCCATGTCCTTTTTTGCGACAAGGCGAACTGGGGAAGTGATTTCACGCTT
TACCGACGCTAACTCTATCATCGATGCTCTTGCTTCAACAATCTTATCGCTTTTTCTCGATGTGAGTATCCTTTTCATCG
TTGGCAGTGTCTTGATTTTGCAAAATGCGAAACTCTTCTTAATAACCTTAATCGCTTTGCCTGTTTATGCCATCATTATC
TTTGCTTTTATGAAGCCTTTTGAGCGAATGAATCATGACGTCATGCAAGCCAATTCTATGGTCAGCTCTGCCATTATTGA
AGATATCAACGGGATTGAAACCATTAAATCACTAACTAGCGAAGAGACACGTTATCGCAATATCGATAGCGAATTCGTGG
AATACTTGGATAAAAGTTTCACACTTAATAAATACGAAGCAATGCAAGCCTCACTTAAGCAAGGAGCACGGCTGATTTTA
AATGTGGCTATTCTCTGGTACGGCTCACGTCTCGTTATGACAGGGAATATTTCTGTTGGGCAGTTGATTACCTACAACAC
TCTCTTATCTTACTTCACAAGACCAATGGAAAATATTATTAACTTGCAAACTAAGTTACAGTCAGCAAAAGTTGCTAACA
AGCGTCTTAACGAAGTTTATCTGGTATCTTCTGAATTTGATAACAAACAAGTAATTGATAATCCAGAGTTTCTCAAAGGT
GATCTTGTCTTTGATGATGTTTCTTATAAATACGGCTTTGGACGCGATACTCTTAGTCACATTAAACTTCGTATCAAGGA
AGGTGAAAAAGTTAGTCTCGTCGGCGTCAGTGGTTCTGGAAAAACGACTTTGGCTAAGATGATGGTAAACTTTTATAGTC
CAAATCAAGGTCAAATCACCTTGGGAAGCTACGACTATAAAACTATTGATAAAAAAGTTCTTCGTCAACACATCAACTAC
CTTCCACAACAATCTTACGTCTTTTCTGGAAGTATCCTTGATAATCTCACTTTAGGTGCTTCTGATGCGATTACTCAAGA
AGACATTATCAAGGCCTGTGAAATCGCTGAGATTCGTGCTGACATTGAAGCTATGCCAATGGCTTACCACACTGAATTAT
CAGATGGGGCTGGTTTATCTGGCGGTCAAAAACAACGATTAGCTATTGCCAGAGCACTTCTGACTAAGTCACCCGTCTTA
ATCCTAGATGAAGCAACAAGTGGTCTTGATGTGCTGACCGAAAAACGTGTTATCCACAATTTGTTAGCTTTAAAAGACAA
AACCATTATCTTTGTTGCTCACCGTTTAAGCATTGCCAAGCAAACTGACCATGTCATCGTCCTAGATAAAGGACAAATTA
TCGAACAAGGTCATCACGAGCAACTCATGCAAAATCCTGGCTTTTACGCTCAGCTATTTCAAGAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter transmembrane region (ABC_membrane) (166-436)

• ABC transporter (ABC_tran) (498-647)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	69.144	99.72	0.69
comA	Streptococcus mitis NCTC 12261	65.96	99.021	0.653
comA	Streptococcus mitis SK321	64.972	99.021	0.643
comA	Streptococcus pneumoniae Rx1	64.972	99.021	0.643
comA	Streptococcus pneumoniae D39	64.972	99.021	0.643
comA	Streptococcus pneumoniae R6	64.972	99.021	0.643
comA	Streptococcus pneumoniae TIGR4	64.972	99.021	0.643
comA	Streptococcus gordonii str. Challis substr. CH1	63.764	99.58	0.635