Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   GO995_RS02490 Genome accession   NZ_CP046624
Coordinates   464359..466248 (+) Length   629 a.a.
NCBI ID   WP_157628768.1    Uniprot ID   -
Organism   Streptococcus ruminicola strain CNU_G3     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 459359..471248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO995_RS02475 (GO995_02475) fmt 461337..462272 (+) 936 WP_074561288.1 methionyl-tRNA formyltransferase -
  GO995_RS02480 (GO995_02480) rsmB 462262..463584 (+) 1323 WP_157628767.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  GO995_RS02485 (GO995_02485) - 463622..464359 (+) 738 WP_039695890.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  GO995_RS02490 (GO995_02490) pknB 464359..466248 (+) 1890 WP_157628768.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GO995_RS02495 (GO995_02495) liaF 466346..467041 (+) 696 WP_039695888.1 cell wall-active antibiotics response protein LiaF -
  GO995_RS02500 (GO995_02500) - 467038..468063 (+) 1026 WP_157628769.1 sensor histidine kinase -
  GO995_RS02505 (GO995_02505) - 468047..468691 (+) 645 WP_006531177.1 response regulator transcription factor -
  GO995_RS02510 (GO995_02510) - 468816..470216 (+) 1401 WP_157628770.1 Cof-type HAD-IIB family hydrolase -
  GO995_RS02515 (GO995_02515) - 470216..470572 (+) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 629 a.a.        Molecular weight: 68164.14 Da        Isoelectric Point: 6.7917

>NTDB_id=406156 GO995_RS02490 WP_157628768.1 464359..466248(+) (pknB) [Streptococcus ruminicola strain CNU_G3]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSRERKLVFEDTENTKTLPKVTTSTPVPSTTEQLLKKQKAAKVN
REAADNKIAKVKTKKKKSHRMFGTLVKIFFAVVVVAIAIFTYLTLSTPASVNVPDVAGTSLADAKTSLTSAGLKVGDIHK
VASDTVQKGHVIKTDPTAGSSKKEGAKVDIYVSKGASGFKMKDYTGQNYQEVIKELKDKHGISSDKIDVEWITGTNYDGG
TIISQTPGKGTKVASEDKITFKVAAIVMPNLIGYTYQDAIAELTALGLSSSHITVFQADATSSTGYSQVKTPSASAVVVA
QDPYFGAAIEGNVKLYFSSGSEVQPSEVAPSQSVPESSETSETSESSSSSSSSSSTEESSQTDSSSVEQ

Nucleotide


Download         Length: 1890 bp        

>NTDB_id=406156 GO995_RS02490 WP_157628768.1 464359..466248(+) (pknB) [Streptococcus ruminicola strain CNU_G3]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTTGCCAAAGATCTAATTCTTGATAATGAAGAAGTGGCTATCAAAGTCCTTCGAACTAATTATCAAACAGATCAAATTG
CCGTTGCTCGTTTCCAACGTGAAGCGCGTGCCATGGCAGAGCTAAACCATCCAAATATCGTTTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGTTCGGACTTGAAAAAATATATTCAAGACCATGCCCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTGTCTGCGATGACTTTGGCTCATCAACAAGGGATTGTTC
ACCGTGATTTAAAACCACAAAATATTTTGTTAACCAAAGACGGAACGGTCAAAGTTACCGACTTTGGTATCGCTGTAGCC
TTTGCAGAAACAAGTTTAACACAGACAAACTCAATGCTTGGTAGTGTACACTATTTATCACCTGAACAAGCGCGTGGTTC
AAAAGCCACTGTTCAAAGTGATATCTACGCTATGGGGATTATGTTGTTTGAAATGTTGACTGGTCACATCCCATATGATG
GTGATTCAGCTGTTACAATTGCTCTTCAACATTTCCAAAAACCACTTCCATCAATCATTGATGAAAATAAAAATGTTCCA
CAAGCTTTGGAAAATGTTGTCATTAAAGCAACTGCAAAACGTTTGAGTGATCGCTACGCCTCAACTTTTGAGATGAGCCG
TGATTTAATGACTGCTCTTTCATATAATCGCAGTCGTGAACGCAAACTTGTCTTTGAAGATACAGAAAATACGAAGACAC
TTCCAAAAGTAACAACTTCAACACCTGTTCCCTCAACTACGGAACAATTGTTGAAAAAACAAAAAGCGGCTAAAGTTAAT
CGTGAAGCTGCGGATAATAAAATTGCGAAAGTGAAAACGAAGAAGAAAAAATCACATCGTATGTTTGGTACTTTAGTGAA
AATTTTCTTTGCGGTCGTAGTAGTTGCAATTGCTATCTTTACTTACTTGACGCTAAGCACACCAGCTTCAGTCAACGTTC
CAGATGTAGCAGGAACAAGTTTAGCAGATGCTAAGACAAGTTTAACTTCAGCTGGACTTAAAGTTGGTGATATTCATAAA
GTAGCTAGTGATACTGTGCAAAAAGGTCATGTTATTAAGACTGACCCAACAGCAGGTTCATCTAAAAAAGAAGGTGCCAA
AGTTGACATTTATGTGTCAAAAGGAGCATCAGGCTTTAAGATGAAAGATTATACTGGTCAAAACTATCAAGAAGTTATCA
AAGAACTCAAAGATAAGCACGGTATTTCAAGTGATAAGATTGATGTTGAATGGATAACAGGTACTAACTATGACGGTGGT
ACTATCATTAGTCAAACACCTGGAAAAGGTACAAAAGTAGCTAGTGAAGATAAGATTACTTTCAAGGTTGCAGCAATCGT
TATGCCAAACCTTATTGGGTATACTTACCAAGATGCAATTGCTGAATTGACTGCACTTGGCTTATCAAGCTCACATATTA
CAGTATTCCAAGCAGATGCTACTTCATCAACTGGATACTCTCAAGTCAAAACACCATCTGCCTCTGCAGTTGTTGTGGCA
CAAGATCCTTACTTTGGCGCAGCTATTGAAGGAAATGTGAAACTTTACTTCTCATCTGGAAGTGAAGTTCAACCTTCTGA
AGTAGCACCATCTCAATCTGTTCCTGAGTCATCTGAGACAAGTGAAACTAGTGAGTCAAGTTCTTCAAGTAGTAGCAGTA
GCAGCACTGAAGAAAGTTCACAAACCGACTCATCATCAGTTGAACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(507-578)

PASTA domain (PASTA)

(440-503)

PASTA domain (PASTA)

(371-434)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

66.2

90.779

0.601
  stkP/pknB Streptococcus salivarius strain HSISS4

63.095

93.482

0.59
  stkP Streptococcus pneumoniae TIGR4

58.757

84.42

0.496
  stkP Streptococcus pneumoniae D39

58.569

84.42

0.494
  stkP Streptococcus pneumoniae R6

58.569

84.42

0.494
  stkP Streptococcus pneumoniae Rx1

58.38

84.42

0.493

Multiple sequence alignment